Disassembly and reassembly of yeast-derived recombinant human papillomavirus virus-like particles (HPV VLPs)

Journal of Pharmaceutical Sciences

Volumn 95, Issue 10, 2006, Pages 2195-2206

  Mach, Henryk ^a   Volkin, David B ^a,b   Troutman, Robert D ^a   Wang, Bei ^a   Luo, Zheng ^a,c   Jansen, Kathrin U ^a,d   Shi, Li ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b CENTOCOR INC   (United States)

^c LEXICON PHARMACEUTICALS INC   (United States)

^d VaxGen Inc   (United States)

Author keywords

Disassembly; Human papillomavirus (HPV); Reassembly; Stabilization; Viruslike particle (VLP)

Indexed keywords

ANTIGENICITY; ARTICLE; CONDYLOMA; ELECTRON MICROSCOPY; HUMAN PAPILLOMAVIRUS TYPE 11; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 6; IMMUNOGENICITY; IONIC STRENGTH; NONHUMAN; PH; SACCHAROMYCES CEREVISIAE; UTERINE CERVIX CANCER; VIRUS CAPSID; VIRUS EXPRESSION; VIRUS PARTICLE; VIRUS RECOMBINANT; WART VIRUS; YEAST;

EID: 33748864395     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20696     Document Type: Article

References (43)

1. Christensen ND. 2005. Emerging human papillomavirus vaccines. Expert Opin Emerg Drugs 10:5-19.
2. zur Hausen H, de Villiers EM. 1994. Human papillomaviruses. Ann Rev Microbiol 48:427-447.
3. Aggelopoulou EP, Skarlos D, Papadimitriou C, Kittas C. 1999. Human papilloma virus DNA detection in oral lesions in the Greek population. Troungos Anticancer Res 19:1391-1395.
4. Kirnbauer R, Booy G, Cheng N, Lowy DR, Schiller JT. 1992. Papillomavirus L1 major protein self-assembles into virus-like particles that are highly immunogenic. Proc Natl Acad Sci 89:12180-12184.
5. Zhou J, Sun XY, Stenzel DJ, Frazer IH. 1991. Expression of vaccinia recombinant HPV 16 L1 and L2 ORF proteins in epithelial cells is sufficient for assembly of HPV virion-like particles. Virology 185:251-257.
6. Hofmann KJ, Cook JC, Joyce JG, et al. 1995. Sequence determination of human papillomavirus type 6a and assembly of virus-like particles in Saccharomyces cerevisiae. Virology 209:506-518.
7. Li M, Cripe TP, Estes PA, Lyon MK, Rose RC, Garcia RL. 1997. Expression of the human papillomavirus type 11 L1 capsid protein in Escherichia coli: Characterization of protein domains involved in DNA binding and capsid assembly. J Virol 71:2988-2995.
8. Koutsky LA, Ault KA, Wheeler CM, Brown DR, Brr E, Alvarez FB, Chiacchierini LM, Jansen KU. 2002. A controlled trial of a human papillomavirus type 16 vaccine. New Engl J Med 347:1645-1651.
9. Belnap DM, Olson NH, Cladel NM, Newcomb WW, Brown JC, Kreider JW, Christensen ND, Baker TS. 1996. Conserved features in papillomavirus and polyomavirus capsids. J Mol Biol 259:249-263.
10. Chen XS, Garcea RL, Goldberg I, Casini G, Harrison SC. 2000. Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16. Mol Cell 5:557-567.
11. Cook JC, Joyce JG, George HA, et al. 1999. Purification of virus-like particles of recombinant human papillomavirus type 11 major capsid protein L1 from Saccharomyces cerevisiae. Prot Expr Purif 17:477-484.
12. Kawana K, Yoshikawa H, Taketani Y, Yoshike K, Kanda T. 1998. In vitro construction of pseudovirions of human papillomavirus type 16: Incorporation of plasmid DNA into reassembled L1/L2 capsids. J Virol 72:10298-10300.
13. McCarthy MP, White WI, Palmer-Hill F, Koenig S, Suzich JA. 1998. Quantitative disassembly and reassembly of human papillomavirus type 11 virus-like particles in vitro. J Virol 72:32-41.
14. Mach H, Volkin DB, Burke CJ, Middaugh CR. 1995. Ultraviolet absorption spectroscopy. Methods Mol Biol 40:91-114.
15. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Geoke NM, Olson BJ, Klenk DC. 1985. Measurement of protein using bicinchoninic acid. Anal Biochem 150:76-85.
16. Koppel DE. 1972. Analysis of macromolecular polydispersity in intensity correlation spectroscopy: The method of cumulants. J Chem Phys 37:4814-4820.
17. Laue T. 2001. Biophysical studies by ultracentrifugation. Curr Opin Struct Biol 11:579-583.
18. Stafford WF. 1992. Boundary analysis in sedimentation transport experiments: A procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile. Anal Biochem 203:295-301.
19. Philo JS. 1997. An improved function for fitting sedimentation velocity data for low-molecular-weight solutes. Biophys J 72:435-444.
20. Shi L, Sanyal G, Ni A, Wang B, Luo Z, Doshna S, Graham TL, Volkin DB. 2005. Stabilization of human papillomavirus virus-like particles by non-ionic surfactant. J Pharm Sci 94:1538-1551.
21. Mach H, Middaugh CR. 1994. Simultaneous monitoring of the environment of tryptophan, tyrosine, and phenylalanine residues in proteins by near-ultraviolet second-derivative spectroscopy. Anal Biochem 222:323-331.
22. Zhou J, Sun XY, Louis K, Frazer IH. 1994. Interaction of human papillomavirus (HPV) type 16 capsid proteins with HPV DNA requires an intact L2 N-terminal sequence. J Virol 68:619-625.
23. Touze A, Coursaget P. 1998. In vitro gene transfer using human papillomavirus-like particles. Nuclei Acid Res 26:1317-1323.
24. Goldmann C, Petry H, Frye S, Ast O, Ebistch S, Jentsch KD, Kaup FJ, Weber F, Trebst C, Nisslein T, Hunsmann G, Weber T, Luke W. 1999. Molecular cloning and expression of major structural protein VP1 of the human polyomavirus JC virus: Formation of virus-like particles useful for immunological and therapeutic studies. J Virol 73:4465-4469.
25. Zhao KN, Hengst K, Liu WJ, Liu YH, Liu XS, McMillan NA, Frazer IH. 2000. BPV1 E2 protein enhances packaging of full-length plasmid DNA in BPV1 pseudovirions. Virology 272:382-393.
26. Liu Y, Frazer IH, Liu WJ, Liu XS, McMillan N, Zhao KN. 2001. Efficiency of delivery of DNA to cells by bovine papillomavirus type-1 L1/L2 pseudovirions. Appl Microbiol Biotechnol 56:150-156.
27. Touze A, Bousarghin L, Ster C, Combita AL, Roingeard P, Coursaget P. 2001. Gene transfer using human polyomavirus BK virus-like particles expressed in insect cells. J Gen Virol 82:3005-3009.
28. Salunke DM, Caspar DLD, Garcea RL. 1986. Self-assembly of purified polyomavirus capsid protein VP1. Cell 46:895-904.
29. Brady JN, Winston VD, Consigli RA. 1977. Dissociation of polyoma virus by the chelation of calcium ions found associated with purified virions. J Virol 23:717-724.
30. Salunke DM, Caspar DLD, Garcea RL. 1989. Polymorphism in the assembly of polyomavirus capsid protein VP1. Biophys J 56:887-900.
31. Yuen LKC, Consigli RA. 1983. Generation of capsids from unstable polyoma virions. J Virol 47:620-625.
32. Garcea RL, Salunke DM, Caspar DLD. 1987. Site-directed mutation affecting polyomavirus capsid self-assembly in vitro. Nature (London) 329:86-87.
33. Sapp M, Volpers C, Muller M, Streeck RE. 1995. Organization of the major and minor capsid proteins in human papillomavirus type 33 virus-like particles. J Gen Virol 76:2407-2412.
34. Paintsil J, Muller M, Picken M, Gissman L, Zhou J. 1998. Calcium is required in reassembly of bovine papillomavirus in vitro. J Gen Virol 79:1133-1141.
35. Liddington RC, Yan Y, Moulai J, Sahli R, Benjamin TL, Harrison SC. 1991. Structure of simian virus 40 at 3.8A resolution. Nature (London) 354:278-284.
36. Stehle T, Gamblin SJ, Yan Y, Harrison SC. 1996. The structure of simian virus 40 refined at 3.1 Å resolution. Structure 4:165-182.
37. Kiselev NA, Klug A. 1969. The structure of viruses of the papilloma-polyoma type V. Tubular variants built of pentamers. J Mol Biol 40:155-171.
38. Baker TS, Caspar DLD, Murakami WT. 1983. Polyoma virus 'hexamer' tubes consist of paired pentamers. Nature 303:446-448.
39. Caspar DLD. 1963. Assembly and stability of the tobacco mosaic virus particle. Adv Protein Chem 18:17-31.
40. Durham ACH, Hendry DA, Von Wechman MB. 1977. Does calcium ion binding control plant virus disassembly? Virology 77:524-533.
41. Harrison SC. 1980. Protein interfaces and inter-subunit bonding. The case of tomato bushy stunt virus. Biophys J 32:139-153.
42. Rossmann MG, Abad-Zapatero C, Hermodson MA, Erikson JW. 1983. Subunit interaction in southern bean mosaic virus. J Mol Biol 166:37-83.
43. Zhao Q, Guo H, Wang Y, Washabaugh MW, Sitrin RD. 2005. Visualization of discrete L1 oligomers in human papillomavirus 16 virus-like particles by gel electrophoresis. J Virol Methods 127:133-140.