Oxidation sensitivity of the catalytic cysteine of the protein-tyrosine phosphatases SHP-1 and SHP-2

Free Radical Biology and Medicine

Volumn 43, Issue 1, 2007, Pages 100-110

  Weibrecht, Irene ^a,b   Böhmer, Sylvia Annette ^b   Dagnell, Markus ^c   Kappert, Kai ^c   Östman, Arne ^c   Böhmer, Frank D ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Modified in gel assay; Ox PTP antibody; Oxidation; Protein tyrosine phosphatase; SH2 domains

Indexed keywords

CATHEPSIN B; CYSTEINE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GROWTH FACTOR; HYBRID PROTEIN; HYDROGEN PEROXIDE; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; STEROID RECEPTOR COACTIVATOR 1;

ALKYLATION; ANTIGEN ANTIBODY REACTION; ARTICLE; CATALYSIS; CELL FUNCTION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; OXIDATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS; ULTRAVIOLET IRRADIATION;

CATALYTIC DOMAIN; CELL LINE; CYSTEINE; HUMANS; HYDROGEN PEROXIDE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; OXIDATION-REDUCTION; PROTEIN-TYROSINE-PHOSPHATASE; SHP1 PROTEIN TYROSINE PHOSPHATASE; SRC HOMOLOGY DOMAINS;

EID: 34249870112     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.03.021     Document Type: Article

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