Lack of mitochondrial depolarization by oxidative stress is associated with resistance to buthionine sulfoximine in acute lymphoblastic leukemia cells

Leukemia Research

Volumn 31, Issue 9, 2007, Pages 1293-1301

  Goto, Hiroaki ^a   Yanagimachi, Masakatsu ^a   Kajiwara, Ryosuke ^a   Kuroki, Fumiko ^a   Yokota, Shumpei ^a  

^a YOKOHAMA CITY UNIVERSITY HOSPITAL   (Japan)

Author keywords

Acute lymphoblastic leukemia; Buthionie sulfoximine; Glutathione; Mitochondria; Oxidative stress

Indexed keywords

2 METHOXYESTRADIOL; BUTHIONINE SULFOXIMINE; GLUTATHIONE; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC ANTIMETABOLITE; HYDROGEN PEROXIDE; OXIDIZING AGENT; PREDNISOLONE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; ACUTE LYMPHOCYTIC LEUKEMIA; CELL CULTURE; CELL MEMBRANE POTENTIAL; CELL PROLIFERATION; DRUG EFFECT; DRUG RESISTANCE; METABOLISM; MITOCHONDRION; PATHOLOGY;

ANTI-INFLAMMATORY AGENTS; ANTIMETABOLITES, ANTINEOPLASTIC; BUTHIONINE SULFOXIMINE; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; LEUKEMIA, LYMPHOCYTIC, ACUTE; MEMBRANE POTENTIALS; MITOCHONDRIA; OXIDANTS; OXIDATIVE STRESS; PREDNISOLONE; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 34249869305     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2007.01.003     Document Type: Article

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