Prognostic significance of cytogenetically detected chromosome 21 anomalies in childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study

Cancer Genetics and Cytogenetics

Volumn 175, Issue 2, 2007, Pages 117-124

  Cooley, Linda D ^a   Chenevert, Saleen ^b   Shuster, Jonathan J ^c   Johnston, Dennis A ^d   Mahoney, Donald H ^e   Carroll, Andrew J ^f   Devidas, Meenakshi ^c   Linda, Stephen B ^c   Lauer, Stephen J ^g   Camitta, Bruce M ^h  

^a UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d BAYLOR UNIVERSITY   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^g EMORY UNIVERSITY   (United States)

^h MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR RUNX1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CANCER GENETICS; CANCER SURVIVAL; CHILD; CHILDHOOD CANCER; CHILDHOOD LEUKEMIA; CHROMOSOME 21; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; CYTOGENETICS; FEMALE; GENE REARRANGEMENT; HUMAN; HUMAN CELL; KAPLAN MEIER METHOD; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MONOSOMY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 21; CYTOGENETIC ANALYSIS; FEMALE; HUMANS; INFANT; LEUKEMIA, LYMPHOCYTIC, ACUTE; MALE; PROGNOSIS;

EID: 34249818756     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2007.02.007     Document Type: Article

References (27)

1. Smith M., Arthur D., Camitta B., Carroll A.J., Crist W., Gaynon P., Gelber R., Heerema N., Korn E.L., Link M., Murphy S., Pui C.H., Pullen J., Reamon G., Sallan S.E., Sather H., Shuster J., Simon R., Trigg M., Tubergen D., Uckun F., and Ungerleider R. Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. J Clin Oncol 14 (1996) 18-24
2. Pui C.H., Relling M.V., and Downing J.R. Mechanisms of disease: acute lymphoblastic leukemia. N Engl J Med 350 (2004) 1535-1548
3. Pui C.H., Sandlund J.T., Pei D., Campana D., Rivera G.K., Ribeiro R.C., Rubnitz J.E., Razzouk I., Howard S.C., Hudson M.M., Cheng C., Kun L.E., Raimondi S.C., Behm F.G., Downing J.R., Relling M.V., and Evans W.E. Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital. Blood 104 (2004) 2690-2696
4. Trueworthy R., Shuster J., Look T., Crist W., Borowitz M., Carroll A., Frankel L., Harris M., Wagner H., and Haggard M. Ploidy of lymphoblasts is the strongest predictor of treatment outcome in B progenitor cell ALL of childhood: a Pediatric Oncology Group study. J Clin Oncol 10 (1992) 606-613
5. Martin P.L., Look A.T., Schnell S., Harris M.B., Pullen J., Shuster J.J., Carroll A.J., Pettenati M.J., and Rao P.N. Comparison of fluorescence in situ hybridization, cytogenetic analysis, and DNA index analysis to detect chromosomes 4 and 10 aneuploidy in pediatric acute lymphoblastic leukemia: a Pediatric Oncology Group study. J Pediatr Hematol Oncol 18 (1996) 113-121
6. Heerema N.A., Sather H.N., Sensel M.G., Zhang T., Hutchinson R.J., Nachman J.B., Lange B.J., Steinherz P.G., Bostrom B.C., Reaman G.H., Gaynon P.S., and Uckun F.M. Prognostic impact of trisomies of chromosomes 10, 17, and 5 among children with acute lymphoblastic leukemia and high hyperdiploidy (>50 chromosomes). J Clin Oncol 18 (2000) 1876-1887
7. Sutcliffe M.J., Shuster J.J., Sather H.N., Camitta B.M., Pullen J., Schultz K.R., Borowitz M.J., Gaynon P.S., Carroll A.J., and Heerema N.A. High concordance from independent studies by the Children's Cancer Group (CCG) and Pediatric Oncology Group (POG) associating favorable prognosis with combined trisomies 4, 10, and 17 in children with NCI standard-risk B-precursor acute lymphoblastic leukemia: a Children's Oncology Group (COG) initiative. Leukemia 19 (2005) 734-740
8. Raimondi S.C., Zhou Y., Mathew S., Shurtleff S.A., Sandlund J.T., Rivera G.K., Behm F.G., and Pui C.H. Reassessment of the prognostic significance of hypodiploidy in pediatric patients with acute lymphoblastic leukemia. Cancer 98 (2003) 2715-2722
9. Land V., Shuster J., Christ W.M., Ravindranath Y., Harris M.B., Krance R.A., Pinkel D., and Pullen D.J. Comparison of two schedules of intermediate dose methotrexate and cytarabine consolidation therapy for childhood B-precursor cell acute lymphoblastic leukemia: a POG study. J Clin Oncol 12 (1994) 1939-1945
10. Harris M., Shuster J.J., Pullen D.J., Borowitz M.J., Carroll A.J., Behm F.G., and Land V.J. Consolidation with anti-metabolite based therapy in standard risk acute lymphocytic leukemia: a Pediatric Oncology Group study. J Clin Oncol 16 (1998) 2840-2847
11. Harris M., Shuster J.J., Pullen J., Borowitz M.J., Carroll A.J., Behm F.G., Camitta B., and Land V.J. Treatment of children with early pre-B and pre-B acute lymphoblastic leukemia with antimetabolite-based intensification regimens: a Pediatric Oncology Group study. Leukemia 14 (2000) 1570-1576
12. Lauer S., Shuster J.J., Mahoney Jr. D.H., Winick N., Toledano S., Munoz L., Kiefer G., Pullen J.D., Steuber C.P., and Camitta B.M. A comparison of early intensive methotrexate/mercaptopurine with early intensive alternating therapy for high risk B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group Phase III randomized trial. Leukemia 15 (2001) 1038-1045
13. Maloney K.W., Shuster J.J., Murphy S., Pullen J., and Camitta B.A. Long-term results of treatment studies in childhood acute lymphoblastic leukemia: Pediatric Oncology Group studies from 1986-1994. Leukemia 14 (2000) 2276-2285
14. Mahoney D.H., Shuster J.J., Nitschke R., Lauer S., Steuber C.P., and Camitta B. Intensification with intermediate dose intravenous methotrexate is effective for children with lower risk B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group study. J Clin Oncol 18 (2000) 1285-1294
15. Mitelman F, editor. ISCN 1991: Guidelines for cancer cytogenetics. Supplement to an International System for Human Cytogenetic Nomenclature. In: Basel: S. Karger, 1991.
16. ISCN 2005: an international system for human cytogenetic nomenclature (2005). In: Shaffer L.G., and Tommerup N. (Eds) (2005), S. Karger, Basel
17. Cox D.R. Regression models and life tables. J R Stat Soc Ser B 34 (1972) 187-220
18. Kaplan E.L., and Meier P. Nonparametric estimator from incomplete observations. J Am Stat Assoc 53 (1958) 457-481
19. Peto R., Pike M.C., Armitage P.K., Breslow N.E., Cox D.R., Howard S.V., Mantel N., McPherson K., Peto J., and Smith P.G. Design and analysis of randomized clinical trials requiring prolonged observation of each patient: II. Analysis and examples. Br J Cancer 35 (1977) 1-39
20. Rubnitz J.E., Downing J.R., Pui C.H., Shurtleff S.A., Raimondi S.C., Evans W.E., Head D.R., Crist W.M., Rivera G.K., Hancock M.L., Boyett J.M., Buijs A., Grosveld G., and Behm F.G. TEL gene rearrangement in acute lymphoblastic leukemia: a new genetic marker with prognostic significance. J Clin Oncol 15 (1997) 1150-1157
21. Niini T., Kanerva J., Vettenranta K., Saarinen-Pihkala U.M., and Knuutila S. AML1 gene amplification: a novel finding in childhood acute lymphoblastic leukemia. Haematologica 85 (2000) 362-366
22. Mikhail F.M., Serry K.A., Hatem N., Mourad Z.I., Farawela H.M., El Kaffash D.M., Coignet L., and Nucifora G. AML1 gene over-expression in childhood acute lymphoblastic leukemia. Leukemia 16 (2002) 658-668
23. Penther D., Preudhomme C., Talmant P., Roumier C., Godon A., Mechinaud F., Milpied N., Bataille R., and Avet-Loiseau H. Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation. Leukemia 16 (2002) 1131-1134
24. Soulier J., Trakhtenbrot L., Najfeid V., Lipton J.M., Mathew S., Avet-Loiseau H., De Braekeleer M., Salem S., Baruchel A., Raimondi S.C., and Raynaud S.D. Amplification of band q22 of chromosome 21, including AML1, in older children with acute lymphoblastic leukemia: an emerging molecular cytogenetic subgroup. Leukemia 17 (2003) 1670-1682
25. Harewood L., Robinson H., Harris R., Al-Obaidi M.J., Jalali G.R., Martineau M., Moorman A.V., Sumption N., Richards S., Mitchell C., and Harrison C.J. Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases. Leukemia 17 (2003) 547-553
26. Robinson H.M., Broadfield Z.J., Cheung K.L., Harewood L., Harris R.L., Jalali G.R., Martineau M., Moorman A.V., Taylor K.E., Richards S., Mitchell C., and Harrison C.J. Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome. Leukemia 17 (2003) 2249-2250
27. Strefford J.C., van Delft F.W., Robinson H.M., Worley H., Yiannikouris O., Selzer R., Richmond T., Hann I., Bellotti T., Raghavan M., Young B.D., Saha V., and Harrison C.J. Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21. Proc Natl Acad Sci U S A 103 (2006) 8167-8172