Comparison of Fluorescence in Situ Hybridization, Cytogenetic Analysis, and DNA Index Analysis to Detect Chromosomes 4 and 10 Aneuploidy in Pediatric Acute Lymphoblastic Leukemia: A Pediatric Oncology Group Study

Journal of Pediatric Hematology/Oncology

Volumn 18, Issue 2, 1996, Pages 113-121

  Martin, Paul L ^a,h   Look, A Thomas ^b   Schnell, Scheryl ^a   Harris, Michael B ^c   Pullen, Jeanette ^d   Shuster, Jonathan J ^e   Carroll, Andrew J ^f,g   Pettenati, Mark J ^a   Rao, P Nagesh ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^g Pediatric Oncology Group   (United States)

^h Bowman Gray School of Medicine ^*  (United States)

Author keywords

Acute lymphoblastic leukemia; Chromosomes; DNA Index; Fluorescence in situ hybridization

Indexed keywords

DNA;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANEUPLOIDY; ARTICLE; BONE MARROW; CHILD; CHROMOSOME 10; CHROMOSOME 4; CHROMOSOME ANALYSIS; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; TRISOMY;

ANEUPLOIDY; CHILD; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 4; DNA PROBES; DNA, NEOPLASM; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; MALE;

EID: 0029894820     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-199605000-00004     Document Type: Article

References (23)

1. Secker-Walker LM, Swansbury GS, Hardisty RM, et al. Cytogenetic of acute lymphoblastic leukemia in children as a factor in the prediction of long-term survival. Br J Haematol 1982;52:389-99.
2. Williams DL, Tsiatis A, Brodeur CM, et al. Prognostic importance of chromosome number in 136 untreated children with acute lymphoblastic leukemia. Blood 1982;60:864-71.
3. Williams DL, Look T, Melvin SL, et al. New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia. Cell 1984;36:101-9.
4. Bloomfield CD, Goldman AI, Alimena G, et al. Chromosomal abnormalities identify high-risk and low-risk patients with acute lymphoblastic leukemia. Blood 1986;67:415-20.
5. Crist W, Pullen J, Boyett J, et al. Clinical and biologic features predict a poor prognosis in acute lymphoid leukemias in infants: a Pediatric Oncology Group Study. Blood 1986;67:135-40.
6. Pui C-H, Raimondi SC, Murphy SB, et al. An analysis of leukemic cell chromosomal features in infants. Blood 1987;69:1289-93.
7. Crist W, Furman W, Strother D, Pui C. Acute lymphocytic leukemia in childhood: immunologic marker, cytogenetic, and molecular studies. South Med J 1988;80:841-7.
8. Santana VM, Dodge RK, Crist WM, et al. Presenting features and treatment outcome of adolescents with acute lymphoblastic leukemia. Leukemia 1990;4:87-90.
9. Look AT. Pathobiology of the acute lymphoid leukemia cell. In: Benz EJ, Cohen HJ, Furie B, et al., eds.Hematology: basic principles and practice, 2nd ed. New York: Churchill Livingstone, 1994:1046-66.
10. Secker-Walker LM, Lawler SD, Hardisty RM. Prognostic implication of chromosomal findings in acute lymphoblastic leukemia at diagnosis. Br Med J 1978;2:1529-30.
11. Williams DL, Harber J, Murphy SB, et al. Chromosomal translocation play a unique role in influencing prognosis in childhood acute lymphoblastic leukemia. Blood 1986;68:205-12.
12. Look AT, Melvin SL, Williams DL, et al. Aneuploidy and percentage of S-phase cells determined by flow cytometry correlate with cell phenotype of childhood acute leukemia. Blood 1982;60:959-67.
13. Look AT, Roberson PK, Williams DL, et al. Prognostic importance of blast cell DNA content in childhood acute lymphoblastic leukemia. Blood 1985;65:1079-86.
14. Harris MB, Shuster JJ, Carroll A, et al. Trisomy of leukemic cell chromosome 4 and chromosome 10 identifies children with B-progenitor cell acute lymphoblastic leukemia with a very low risk of treatment failure - A Pediatric Oncology Group study. Blood 1992;79:3316-24.
15. Pui C-H, Crist W, Look A. Biology and clinical significance of cytogenetic abnormalities in childhood acute lymphoblastic leukemia. Blood 1990;76:1449-63.
16. Andreeff M, Conjalka M, Jhanwar S, et al. Clonal abnormalities in acute lymphoblastic leukemia: comparison of cytogenetics and flow cytometry. Blood 1982;60:120a.
17. Barlogie B, Raber MN, Schumann J, et al. Flow cytometry in clinical cancer research. Cancer Res 1983;43:3982-97.
18. Heinonen K, Rautonen J, Siimes MA, et al. Cytogenetic study of 105 children with acute lymphoblastic leukemia. Eur J Haematol 1988;41:237-242.
19. Jenkins RB, LeBeau MM, Kraker WJ, et al. Fluorescence in situ hybridization - a sensitive method for trisomy-8 detection in bone marrow specimens. Blood 1992;79:3307-15.
20. Qumsiyeh MB, Tharapel SA. Interphase detection of trisomy 12 in B-cell chronic lymphocytic leukemia by fluorescence hybridization in situ. Leukemia 1992;6:602-5.
21. Kadam P, Umerani A, Srivastava A, et al. Combination of classical and interphase cytogenetics to investigate the biology of myeloid disorders: detection of masked monosomy 7 in AML. Leukemia Res 1993;17:365-74.
22. Romana SP, Cherif D, Le Coniat ML, et al. In situ hybridization to interphase nuclei in acute leukemia. Genes Chrom Cancer 1993;8:98-103.
23. Que TH, Marco JG, Ellis J, et al. Trisomy 12 in chronic lymphocytic leukemia detected by fluorescence in situ hybridization: analysis by stage, immunophenotype, and morphology. Blood 1993;82:571-5.