Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential

FEBS Journal

Volumn 274, Issue 12, 2007, Pages 3003-3012

  Van Der Toorn, Marco ^a   Kauffman, Henk F ^b   Van Der Deen, Margaretha ^a   Slebos, Dirk Jan ^a   Koëter, Gerard H ^a   Gans, Rijk O B ^a   Bakker, Stephan J L ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Cyclosporin A; Mitochondria; Mitochondrial membrane potential; Mitochondrial permeability transition; Reactive oxygen species

Indexed keywords

5 CHLOROMETHYL 2',7' DICHLORODIHYDROFLUORESCEIN DIACETATE ACETYL ESTER; 5,5',6,6' TETRACHLORO 1,1',3,3' TETRAETHYLBENZIMIDAZOLYLCARBOCYANINE IODIDE; 6 CHLOROMETHYL 2',7' DICHLORODIHYDROFLUORESCEIN DIACETATE ACETYL ESTER; ADENOSINE TRIPHOSPHATE; CALCIUM ION; CARBOCYANINE; CYCLOSPORIN A; CYCLOSPORIN DERIVATIVE; FLUO 3; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE; GLYCOPROTEIN P; IODINE DERIVATIVE; N METHYL 4 ISOLEUCINE CYCLOSPORIN; NIM 811; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VALSPODAR;

ARTICLE; BIOSYNTHESIS; CALCIUM HOMEOSTASIS; CANCER CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; FLUORESCENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; KIDNEY CELL; LIVER CYTOSOL; LIVER MITOCHONDRION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMALL CELL CARCINOMA; SWINE;

ANILINE COMPOUNDS; ANIMALS; BENZIMIDAZOLES; CALCIUM; CARBOCYANINES; CELL LINE; CYCLOSPORINE; CYTOPLASM; FLUORESCEINS; FLUORESCENT DYES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; P-GLYCOPROTEIN; REACTIVE OXYGEN SPECIES; SWINE; XANTHENES;

SUIDAE;

EID: 34249791819     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.05827.x     Document Type: Article

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