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Volumn 13, Issue 15, 2007, Pages 2166-2173

Therapeutic and prophylactic thalidomide in TNBS-induced colitis: Synergistic effects on TNF-α, IL-12 and VEGF production

Author keywords

Experimental colitis; IL 12; Inflammatory bowel disease; Thalidomide; Tumor necrosis factor ; Vascular endothelial growth factor

Indexed keywords

ALCOHOL; CD4 ANTIGEN; INTERLEUKIN 12; PLACEBO; THALIDOMIDE; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 34249790170     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v13.i15.2166     Document Type: Article
Times cited : (25)

References (48)
  • 1
    • 0031781603 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Etiology and pathogenesis
    • Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998; 115: 182-205
    • (1998) Gastroenterology , vol.115 , pp. 182-205
    • Fiocchi, C.1
  • 2
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002; 347: 417-429
    • (2002) N Engl J Med , vol.347 , pp. 417-429
    • Podolsky, D.K.1
  • 3
    • 0034326706 scopus 로고    scopus 로고
    • The role of chemokines and chemokine receptors in mucosal inflammation
    • Papadakis KA, Targan SR. The role of chemokines and chemokine receptors in mucosal inflammation. Inflamm Bowel Dis 2000; 6: 303-313
    • (2000) Inflamm Bowel Dis , vol.6 , pp. 303-313
    • Papadakis, K.A.1    Targan, S.R.2
  • 4
    • 0027451455 scopus 로고
    • Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
    • Reinecker HC, Steffen M, Witthoeft T, Pflueger I, Schreiber S, MacDermott RP, Raedler A. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol 1993; 94: 174-181
    • (1993) Clin Exp Immunol , vol.94 , pp. 174-181
    • Reinecker, H.C.1    Steffen, M.2    Witthoeft, T.3    Pflueger, I.4    Schreiber, S.5    MacDermott, R.P.6    Raedler, A.7
  • 6
    • 0025912981 scopus 로고
    • Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease
    • Murch SH, Lamkin VA, Savage MO, Walker-Smith JA, MacDonald TT. Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease. Gut 1991; 32: 913-917
    • (1991) Gut , vol.32 , pp. 913-917
    • Murch, S.H.1    Lamkin, V.A.2    Savage, M.O.3    Walker-Smith, J.A.4    MacDonald, T.T.5
  • 7
    • 0026531017 scopus 로고
    • Tumour necrosis factor alpha in stool as a marker of intestinal inflammation
    • Braegger CP, Nicholls S, Murch SH, Stephen S, MacDonald TT. Tumour necrosis factor alpha in stool as a marker of intestinal inflammation. Lancet 1992; 339: 89-91
    • (1992) Lancet , vol.339 , pp. 89-91
    • Braegger, C.P.1    Nicholls, S.2    Murch, S.H.3    Stephen, S.4    MacDonald, T.T.5
  • 11
    • 0030995575 scopus 로고    scopus 로고
    • Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
    • Monteleone G, Biancone L, Marasco R, Morrone G, Marasco O, Luzza F, Pallone F. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997; 112: 1169-1178
    • (1997) Gastroenterology , vol.112 , pp. 1169-1178
    • Monteleone, G.1    Biancone, L.2    Marasco, R.3    Morrone, G.4    Marasco, O.5    Luzza, F.6    Pallone, F.7
  • 12
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 1995; 182: 1281-1290
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Stuber, E.4    Strober, W.5
  • 13
    • 0031837973 scopus 로고    scopus 로고
    • Increased serum levels of vascular endothelial growth factor in patients with inflammatory bowel disease
    • Griga T, Tromm A, Spranger J, May B. Increased serum levels of vascular endothelial growth factor in patients with inflammatory bowel disease. Scand J Gastroenterol 1998; 33: 504-508
    • (1998) Scand J Gastroenterol , vol.33 , pp. 504-508
    • Griga, T.1    Tromm, A.2    Spranger, J.3    May, B.4
  • 14
    • 0035072493 scopus 로고    scopus 로고
    • VEGF, basic-FGF, and TGF-beta in Crohn's disease and ulcerative colitis: A novel mechanism of chronic intestinal inflammation
    • Kanazawa S, Tsunoda T, Onuma E, Majima T, Kagiyama M, Kikuchi K. VEGF, basic-FGF, and TGF-beta in Crohn's disease and ulcerative colitis: a novel mechanism of chronic intestinal inflammation. Am J Gastroenterol 2001; 96: 822-828
    • (2001) Am J Gastroenterol , vol.96 , pp. 822-828
    • Kanazawa, S.1    Tsunoda, T.2    Onuma, E.3    Majima, T.4    Kagiyama, M.5    Kikuchi, K.6
  • 15
    • 0032928383 scopus 로고    scopus 로고
    • Increased production of vascular endothelial growth factor by intestinal mucosa of patients with inflammatory bowel disease
    • Griga T, Voigt E, Gretzer B, Brasch F, May B. Increased production of vascular endothelial growth factor by intestinal mucosa of patients with inflammatory bowel disease. Hepatogastroenterology 1999; 46: 920-923
    • (1999) Hepatogastroenterology , vol.46 , pp. 920-923
    • Griga, T.1    Voigt, E.2    Gretzer, B.3    Brasch, F.4    May, B.5
  • 16
    • 2442657641 scopus 로고    scopus 로고
    • Infliximab downregulates basic fibroblast growth factor and vascular endothelial growth factor in Crohn's disease patients
    • Di Sabatino A, Ciccocioppo R, Benazzato L, Sturniolo GC, Corazza GR. Infliximab downregulates basic fibroblast growth factor and vascular endothelial growth factor in Crohn's disease patients. Aliment Pharmacol Ther 2004; 19: 1019-1024
    • (2004) Aliment Pharmacol Ther , vol.19 , pp. 1019-1024
    • Di Sabatino, A.1    Ciccocioppo, R.2    Benazzato, L.3    Sturniolo, G.C.4    Corazza, G.R.5
  • 19
    • 0027441787 scopus 로고
    • Chronic cutaneous lupus erythematosus treated with thalidomide
    • Holm AL, Bowers KE, McMeekin TO, Gaspari AA. Chronic cutaneous lupus erythematosus treated with thalidomide. Arch Dermatol 1993; 129: 1548-1550
    • (1993) Arch Dermatol , vol.129 , pp. 1548-1550
    • Holm, A.L.1    Bowers, K.E.2    McMeekin, T.O.3    Gaspari, A.A.4
  • 20
    • 0033168605 scopus 로고    scopus 로고
    • Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
    • Corral LG, Haslett PA, Muller GW, Chen R, Wong LM, Ocampo CJ, Patterson RT, Stirling DI, Kaplan G. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol 1999; 163: 380-386
    • (1999) J Immunol , vol.163 , pp. 380-386
    • Corral, L.G.1    Haslett, P.A.2    Muller, G.W.3    Chen, R.4    Wong, L.M.5    Ocampo, C.J.6    Patterson, R.T.7    Stirling, D.I.8    Kaplan, G.9
  • 22
    • 0032714591 scopus 로고    scopus 로고
    • Thalidomide therapy for patients with refractory Crohn's disease: An open-label trial
    • Ehrenpreis ED, Kane SV, Cohen LB, Cohen RD, Hanauer SB. Thalidomide therapy for patients with refractory Crohn's disease: an open-label trial. Gastroenterology 1999; 117: 1271-1277
    • (1999) Gastroenterology , vol.117 , pp. 1271-1277
    • Ehrenpreis, E.D.1    Kane, S.V.2    Cohen, L.B.3    Cohen, R.D.4    Hanauer, S.B.5
  • 24
    • 0030925172 scopus 로고    scopus 로고
    • Treatment with tumour necrosis factor inhibitor oxpentifylline does not improve corticosteroid dependent chronic active Crohn's disease
    • Bauditz J, Haemling J, Ortner M, Lochs H, Raedler A, Schreiber S. Treatment with tumour necrosis factor inhibitor oxpentifylline does not improve corticosteroid dependent chronic active Crohn's disease. Gut 1997; 40: 470-474
    • (1997) Gut , vol.40 , pp. 470-474
    • Bauditz, J.1    Haemling, J.2    Ortner, M.3    Lochs, H.4    Raedler, A.5    Schreiber, S.6
  • 25
    • 3242721681 scopus 로고    scopus 로고
    • Commission on Life Sciences, National Research Council. Guide for the Care and Use of Laboratory animals. Washington, DC. National Academy Press
    • Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council. Guide for the Care and Use of Laboratory animals. Washington, DC. National Academy Press, 1996.
    • (1996) Institute of Laboratory Animal Resources
  • 26
    • 0034858965 scopus 로고    scopus 로고
    • Thalidomide impairment of trinitrobenzene sulphonic acid-induced colitis in the rat - role of endothelial cell-leukocyte interaction
    • Lienenluke B, Stojanovic T, Fiebig T, Fayyazi A, Germann T, Hecker M. Thalidomide impairment of trinitrobenzene sulphonic acid-induced colitis in the rat - role of endothelial cell-leukocyte interaction. Br J Pharmacol 2001; 133: 1414-1423
    • (2001) Br J Pharmacol , vol.133 , pp. 1414-1423
    • Lienenluke, B.1    Stojanovic, T.2    Fiebig, T.3    Fayyazi, A.4    Germann, T.5    Hecker, M.6
  • 27
    • 0034924028 scopus 로고    scopus 로고
    • Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease
    • Hahm KB, Im YH, Parks TW, Park SH, Markowitz S, Jung HY, Green J, Kim SJ. Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease. Gut 2001; 49: 190-198
    • (2001) Gut , vol.49 , pp. 190-198
    • Hahm, K.B.1    Im, Y.H.2    Parks, T.W.3    Park, S.H.4    Markowitz, S.5    Jung, H.Y.6    Green, J.7    Kim, S.J.8
  • 32
    • 0034761594 scopus 로고    scopus 로고
    • Transmembrane TNF-alpha, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease
    • van Deventer SJ. Transmembrane TNF-alpha, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease. Gastroenterology 2001; 121: 1242-1246
    • (2001) Gastroenterology , vol.121 , pp. 1242-1246
    • van Deventer, S.J.1
  • 33
    • 0036151047 scopus 로고    scopus 로고
    • Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease
    • ten Hove T, van Montfrans C, Peppelenbosch MP, van Deventer SJ. Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease. Gut 2002; 50: 206-211
    • (2002) Gut , vol.50 , pp. 206-211
    • ten Hove, T.1    van Montfrans, C.2    Peppelenbosch, M.P.3    van Deventer, S.J.4
  • 35
    • 0026080801 scopus 로고
    • Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes
    • Sampaio EP, Sarno EN, Galilly R, Cohn ZA, Kaplan G. Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med 1991; 173: 699-703
    • (1991) J Exp Med , vol.173 , pp. 699-703
    • Sampaio, E.P.1    Sarno, E.N.2    Galilly, R.3    Cohn, Z.A.4    Kaplan, G.5
  • 36
    • 0027230553 scopus 로고
    • Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
    • Moreira AL, Sampaio EP, Zmuidzinas A, Frindt P, Smith KA, Kaplan G. Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med 1993; 177: 1675-1680
    • (1993) J Exp Med , vol.177 , pp. 1675-1680
    • Moreira, A.L.1    Sampaio, E.P.2    Zmuidzinas, A.3    Frindt, P.4    Smith, K.A.5    Kaplan, G.6
  • 37
    • 18744416547 scopus 로고    scopus 로고
    • Thalidomide treatment reduces colon injury induced by experimental colitis
    • Mazzon E, Muia C, Di Paola R, Genovese T, De Sarro A, Cuzzocrea S. Thalidomide treatment reduces colon injury induced by experimental colitis. Shock 2005; 23: 556-564
    • (2005) Shock , vol.23 , pp. 556-564
    • Mazzon, E.1    Muia, C.2    Di Paola, R.3    Genovese, T.4    De Sarro, A.5    Cuzzocrea, S.6
  • 38
    • 0030927340 scopus 로고    scopus 로고
    • In vitro effects of oxpentifylline on inflammatory cytokine release in patients with inflammatory bowel disease
    • Reimund JM, Dumont S, Muller CD, Kenney JS, Kedinger M, Baumann R, Poindron P, Duclos B. In vitro effects of oxpentifylline on inflammatory cytokine release in patients with inflammatory bowel disease. Gut 1997; 40: 475-480
    • (1997) Gut , vol.40 , pp. 475-480
    • Reimund, J.M.1    Dumont, S.2    Muller, C.D.3    Kenney, J.S.4    Kedinger, M.5    Baumann, R.6    Poindron, P.7    Duclos, B.8
  • 42
    • 0036155980 scopus 로고    scopus 로고
    • Thalidomide reduces tumour necrosis factor alpha and interleukin 12 production in patients with chronic active Crohn's disease
    • Bauditz J, Wedel S, Lochs H. Thalidomide reduces tumour necrosis factor alpha and interleukin 12 production in patients with chronic active Crohn's disease. Gut 2002; 50: 196-200
    • (2002) Gut , vol.50 , pp. 196-200
    • Bauditz, J.1    Wedel, S.2    Lochs, H.3
  • 43
    • 33751287711 scopus 로고    scopus 로고
    • Molecular analysis of blood vessel formation and disease
    • Carmeliet P, Collen D. Molecular analysis of blood vessel formation and disease. Am J Physiol 1997; 273: H2091-H2104
    • (1997) Am J Physiol , vol.273
    • Carmeliet, P.1    Collen, D.2
  • 45
    • 2642607848 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins
    • Kevil CG, Payne DK, Mire E, Alexander JS. Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins. J Biol Chem 1998; 273: 15099-15103
    • (1998) J Biol Chem , vol.273 , pp. 15099-15103
    • Kevil, C.G.1    Payne, D.K.2    Mire, E.3    Alexander, J.S.4
  • 46
    • 0032912597 scopus 로고    scopus 로고
    • Elevated serum vascular endothelial growth factor in children and young adults with Crohn's disease
    • Bousvaros A, Leichtner A, Zurakowski D, Kwon J, Law T, Keough K, Fishman S. Elevated serum vascular endothelial growth factor in children and young adults with Crohn's disease. Dig Dis Sci 1999; 44: 424-430
    • (1999) Dig Dis Sci , vol.44 , pp. 424-430
    • Bousvaros, A.1    Leichtner, A.2    Zurakowski, D.3    Kwon, J.4    Law, T.5    Keough, K.6    Fishman, S.7
  • 47
    • 0035831465 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells
    • Kim I, Moon SO, Kim SH, Kim HJ, Koh YS, Koh GY. Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells. J Biol Chem 2001; 276: 7614-7620
    • (2001) J Biol Chem , vol.276 , pp. 7614-7620
    • Kim, I.1    Moon, S.O.2    Kim, S.H.3    Kim, H.J.4    Koh, Y.S.5    Koh, G.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.