Increased serum levels of vascular endothelial growth factor in patients with inflammatory bowel disease

Scandinavian Journal of Gastroenterology

Volumn 33, Issue 5, 1998, Pages 504-508

  Griga, T ^a   Tromm, A ^a   Spranger, J ^a   May, B ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Inflammatory bowel disease; Vascular endothelial growth factor

Indexed keywords

VASCULOTROPIN;

ARTICLE; BLOOD LEVEL; BLOOD VESSEL PERMEABILITY; CLINICAL ARTICLE; CROHN DISEASE; DISEASE ACTIVITY; ENTERITIS; FEMALE; HUMAN; INTESTINE FISTULA; MALE; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; ULCERATIVE COLITIS;

ADULT; ANALYSIS OF VARIANCE; CHI-SQUARE DISTRIBUTION; COLITIS, ULCERATIVE; CROHN DISEASE; ENDOTHELIAL GROWTH FACTORS; FEMALE; HUMANS; IMMUNOASSAY; LYMPHOKINES; MALE; MIDDLE AGED; PROGNOSIS; SENSITIVITY AND SPECIFICITY; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0031837973     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365529850172070     Document Type: Article

References (42)

1. Dvorak HF, Detmar M, Claffey KP, Nagy JA, van de Water L, Senger DR. Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation. Int Arch Allergy Immunol 1995; 107:233-5.
2. Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 1995;55:3964-8.
3. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Senger DR, et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res 1993; 53:4727-35.
4. Brown LF, Yeo KT, Berse B, Yeo TK, Senger DR, Dvorak HF, et al. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J Exp Med 1992;176:1375-9.
5. Frank S, Hubner G, Breier G, Longaker MT, Greenhalgh DG, Werner S. Regulation of VEGF expression in cultured keratinocytes. Implications for normal and impaired wound healing. J Biol Chem 1995;20:12607-13.
6. Burke PA, Lehmann BK, Powell JS. Vascular endothelial growth factor causes endothelial cell proliferation after vascular injury. Biochem Biophys Res Commun 1995;207:348-54.
7. Peters K, de Vries C, Williams L. Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth. Proc Natl Acad Sci 1993;90:8915-9.
8. Brown LF, Olbricht SM, Berse B, Jackman RW, Matsueda G, Tognazzi KA, et al. Overexpression of vascular permeability factor (VPF/VEGF) and its endothelial receptors in delayed hypersensitivity skin reactions. J Immunol 1995;154:2801-7.
9. Ferrara N. Vascular endothelial growth factor - The trigger for neovascularization in the eye [editorial]. Lab Invest 1995;72: 615-8.
10. Liu Y, Cox SR, Morita T, Kourembanas S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer. Circ Res 1995;77:638-43.
11. Minchenko A, Bauer T, Salceda S, Caro J. Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab Invest 1994;71:374-9.
12. Fava RA, Olsen NJ, Spencer-Green G, Yeo TK, Yeo KT, Berse B, et al. Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid arthritis. J Exp Med 1994;180:340-6.
13. Koch E, Harlow I, Haines GK, Amento EP, Unemori EN, Wong WL, et al. Vascular endothelial growth factor: a cytokine modulating endothelial function in rheumatoid arthritis. J Immunol 1994;152:4149-55.
14. Brown LF, Harris TJ, Yeo KT, Stahle-Backdahl M, Jackman RW, Berse B, et al. Increased expression of vascular permeability factor (vascular endothelial growth factor) in bullous pemphigoid, dermatitis herpetiformis and erythema multiforme. J Invest Dermatol 1995;104:744-9.
15. Jakeman LB, Armanini M, Phillips HS, Ferrara N. Developmental expression of binding sites and mRNA for vascular endothelial growth factor suggests a role of this protein in vasculogenesis and angiogenesis. Endocrinology 1993;133:848-59.
16. De Vries C, Escobedo JA, Ueno H, Houck KA, Ferrara N, Williams LT. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992;255:989-91.
17. Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D, et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial growth factor. Biochem Biophys Res Commun 1992;187:1579-86.
18. Berse B, Brown LF, van de Water L, Dvorak HF, Senger DR. Vascular permeability factor (Vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages and tumors. Mol Biol Cell 1992;3:211-20.
19. Iijima K. Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factor. Kidney Int 1993;44:959-66.
20. Stavri GT, Zachary IC, Baskerville PA, Martin JF, Erusalimsky JD. Basic fibroblast growth factor upregulates the expression of vascular endothelial growth factor in vascular smooth muscle cells. Synergistic interaction with hypoxia. Circulation 1995;92: 11-4.
21. Brogi E, Wu T, Namiki A, Isner JM. Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only. Circulation 1994;90:649-52.
22. Brown LF. Vascular permeability factor mRNA and protein expression in human kidney. Kidney Int 1992;42:1457-61.
23. Monacci WT, Merrill MJ, Oldfield EH. Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues. Am J Physiol 1993;264:995-1002.
24. Pertovaara L, Kaipainen A, Mustonen T, Orpana A, Ferrara N, Saksela O, et al. Vascular endothelial growth factor is induced in response to transforming growth factor-β in fibroblastic and epithelial cells. J Biol Chem 1994;269:6271-4.
25. Senger D, van de Water L, Brown L, Nagy J, Yeo KT, Yeo TK, et al. Vascular permeability factor (VPF, VEGF) in tumor biology. Cancer Metast Rev 1993;12:303-24.
26. Baker PN, Krasnow J, Roberts JM, Yeo KT. Elevated serum levels of vascular endothelial growth factor in patients with preeclampsia. Obstet Gynecol 1995;86:815-21.
27. Roberts W, Palade G. Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor. J Cell Sci 1995;108:2369-79.
28. Pepper MS, Ferrara N, Orci L, Montesano R. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 1991;181: 902-6.
29. 2+ and von Willebrand factor release in human endothelial cells. AmJ Pathol 1991;138: 213-21.
30. Shen H, Clauss M, Ryan J, Schmidt AM, Tijburg P, Borden L, et al. Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes. Blood 1993;81:2767-73.
31. Best WR, Becktel JM, Singleton JW, Kern F. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology 1976;70:439-44.
32. Truelove SC, Witts LJ. Cortisone in ulcerative colitis: final report on a therapeutic trial. Br Med J 1955;2:1041-4.
33. Collins PD, Connolly DT, Williams TJ. Characterization of the increase in vascular permeability induced by vascular endothelial growth factor in vivo. Br J Pharmacol 1993;109:195-9.
34. Ito A, Hirota S, Mizuno H, Kawasaki Y, Takemura T, Nishiura T, et al. Expression of vascular permeability factor (VPF/VEGF) messenger RNA by plasma cells: possible involvement in the development of edema in chronic inflammation. Pathol Int 1995;45:715-20.
35. Ku DD, Zaleski JK, Liu S, Brock TA. Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries. Am J Physiol 1993;265:586-92.
36. Xie Q, Cho HJ, Calaycay J, Mumford RA, Swiderek KM, Lee TD, et al. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 1992;256:225-8.
37. Ignarro LJ. Biosynthesis and metabolism of endothelium derived nitric oxide. Annu Rev Pharmacol Toxicol 1990;30: 535-60.
38. Rachmilewitz D, Stamler JS, Karmeli F, Loscalzo J, Xavier RJ, Podolsky DK. Role of nitric oxide in the pathogenesis of IBD. In: Monteiro E, Veloso FT, editors. Inflammatory bowel diseases. New insights into mechanisms of inflammation and challenges in diagnosis and treatment. London: Kluwer Academic Publishers; 1995. p. 53-60.
39. Middleton SJ, Shorthouse M, Hunter JO. Increased nitric oxide synthase in ulcerative colitis. Lancet 1993;341:465-6.
40. Appleton I, Brown NJ, Willis D, Colville-Nash PR, Alam C, Brown JR, et al. Role of vascular endothelial growth factor in a murine chronic granulomatous tissue air pouch model of angiogenesis. J Pathol 1996;180:90-4.
41. Podolsky DK. Petide growth factors in inflammatory bowel disease: role in mucosal tissue repair. In: Targan SR, Shanahan F, editors. Inflammatory bowel disease. From bench to bedside. Baltimore: Williams and Wilkins; 1994. p. 160-70.
42. Sankey EA, Dhillon AP, Anthony A, Wakefield AJ, Sim R, More L, et al. Early mucosal changes in Crohn's disease. Gut 1993;34:375-81.