Thalidomide impairment of trinitrobenzene sulphonic acid-induced colitis in the rat - Role of endothelial cell-leukocyte interaction

British Journal of Pharmacology

Volumn 133, Issue 8, 2001, Pages 1414-1423

  Lienenlüke, Bianca ^a   Stojanovic, Tomislav ^a   Fiebig, Thomas ^a   Fayyazi, Afshin ^a   Germann, Tieno ^b   Hecker, Markus ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b GRÜNENTHAL GMBH   (Germany)

Author keywords

Gene expression; Inflammatory bowel disease; Interleukin 8; Microvascular endothelium; Thalidomide

Indexed keywords

ALCOHOL; INTERLEUKIN 8; MESSENGER RNA; OLIVE OIL; SUPIDIMIDE; THALIDOMIDE; THALIDOMIDE DERIVATIVE; TRINITROBENZENESULFONIC ACID; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAPILLARY DENSITY; CELL INTERACTION; COLITIS; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LEUKOCYTE; MALE; MICROSCOPY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM;

EID: 0034858965     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704193     Document Type: Article

References (38)

1. Role of interleukin 8 on leucocyte-endothelial cell adhesion in intestinal inflammation
2. Expression of CD40 and its ligand, CD40L, in intestinal lesions of Crohn's disease
3. The metabolic fate of supidimide in the rat
4. Endothelin-1 induced leukocyte adhesion in submucosal venules of the rat small intestine
5. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
6. Differential effects of neutrophil-activating peptide 1/IL-8 and its homologues on leukocyte adhesion and phagocytosis
7. Expression of nitric oxide synthases and formation of nitrotyrosine and reactive oxygen species in inflammatory bowel disease
8. Inducer-specific bidirectional regulation of endothelial interleukin-8 production by thalidomide
9. Thalidomide therapy for patients with refractory Crohn's disease: A label trial
10. Experimental models of inflammatory bowel disease
11. Does microcirculation play a role in the pathogenesis of inflammatory bowel diseases? Answers from intravital microscopic studies in animal models
12. Nitric oxide and inflammatory bowel diseases
13. Detrimental effects of octreotide on intestinal microcirculation
14. Pathogenesis of Crohn's disease
15. Effect of thalidomide and structurally related compounds on corneal angiogenesis is comparable to their teratological potency
16. Cytokine-inducible CD40 expression in vascular smooth muscle cells is mediated by nuclear factor κB and signal transducer and activator of transcription I
17. Pressure-induced upregulation of preproendothelin-1 and endothelin B receptor expression in rabbit jugular vein in situ - Implications for vein graft failure?
18. Hyperexpression of CD40 ligand (CD154) in inflammatory bowel disease and its contribution to pathogenic cytokine production
19. Chemokines in the inflammatory bowel diseases
20. Beneficial effects of local or systemic lidocaine in experimental colitis
21. Interleukin-8 and inducible nitric oxide synthase mRNA levels in inflammatory bowel disease at first presentation
22. Roles of ET-1 in endotoxin-induced microcirculatory disturbance in rat small intestine
23. Inhibition of IL-12 production by thalidomide
24. Hapten-induced model of chronic inflammation and ulceration in the rat colon
25. The effect of thalidomide and 2 analogs on collagen induced arthritis
26. Anti-CD11b/CD18 antibodies reduce inflammation in acute colitis in rats
27. Leukocyte-endothelial cell interactions: Molecular mechanisms and implications in gastrointestinal disease
28. Cytokines in inflammatory bowel disease
29. Effects of hydrogen peroxide scavenger catalase on villous microcirculation in the rat small intestine in a model of inflammatory bowel disease
30. Aberrant binding of lamina propria lymphocytes to vascular endothelium in inflammatory bowel diseases
31. Pathogenesis and immune mechanisms of chronic inflammatory bowel diseases
32. Extravasation of leukocytes assessed by intravital microscopy: Effect of thalidomide
33. Pathophysiological role of nitric oxide in rat experimental colitis
34. The pathogenesis of mucosal inflammation in murine models of inflammatory bowel disease and Crohn disease
35. Role of cell adhesion molecules in inflammatory bowel diseases
36. An open-label pilot study of low-dose thalidomide in chronically active, steroid-dependent Crohn's disease
37. Crohn's disease: Pathogenesis and persistent measles virus infection
38. Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase