Formation of carnosine-Cu(II) complexes prevents and reverts the inhibitory action of copper in P2X4 and P2X7 receptors

Journal of Neurochemistry

Volumn 80, Issue 4, 2002, Pages 626-633

  Coddou, Claudio ^a   Villalobos, Claudio ^a   González, Jorge ^a   Acuña Castillo, Claudio ^a   Loeb, Bárbara ^a   Huidobro Toro, J Pablo ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Carnosine; Copper; Copper neuromodulation; Cu(II) carnosine complexes; Metal chelation; P2X receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE; BATHOPHENANTHROLINE; CARNOSINE; COPPER; COPPER COMPLEX; GLYCINE; HISTIDINE; METAL CHELATE; PENICILLAMINE; PHENANTHROLINE DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ARTICLE; CHANNEL GATING; COMPLEX FORMATION; CONCENTRATION RESPONSE; DRUG EFFECT; DRUG POTENCY; DRUG POTENTIATION; INTOXICATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; SPECTROSCOPY; SYNAPSE; SYNAPTIC TRANSMISSION; XENOPUS LAEVIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CARNOSINE; CELLS, CULTURED; CHELATING AGENTS; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; MICROINJECTIONS; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, PURINERGIC P2; SPECTRUM ANALYSIS; XENOPUS LAEVIS;

ANIMALIA; XENOPUS LAEVIS;

EID: 0036329646     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-3042.2001.00732.x     Document Type: Article

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