A new approach to pyrazino[2,1-b]quinazolines and pyrazino[1,2-a]thieno[3, 2-d] pyrimidines

Synthesis

Volumn , Issue 10, 2007, Pages 1503-1508

  Kulik, Svetlana N ^a   Kobko, Alexander S ^b   Tolmachev, Andrey A ^a   Tverdokhlebov, Anton V ^b   Shishkin, Oleg V ^c   Chernega, Alexander N ^d  

^a TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

^b ENAMINE LTD   (Ukraine)

^c INSTITUTE FOR SINGLE CRYSTALS   (Ukraine)

^d INSTITUTE OF ORGANIC CHEMISTRY   (Ukraine)

Author keywords

Alkylations; Heterocycles; Nitriles; Pyrazines; Ring closure

Indexed keywords

PYRAZINES; RING CLOSURE; STARTING MATERIALS;

ACETONE; ALKYLATION; AMINES; SYNTHESIS (CHEMICAL);

ACETONITRILE;

2 (CHLOROMETHYL) 3 (2 OXOPROPYL)QUINAZOLIN 4(3H) ONE; 2 (CHLOROMETHYL) 4 OXO 3,4 DIHYDROQUINAZOLIN 3 YL ACETRONITRILE; 2 (CHLOROMETHYL)QUIANZOLIN 4(3H) ONE; 2 (CHLOROMETHYL)THIENO[2,3 D]PYRIMIDIN 4(3H) ONE DERIVATIVE; 2 3 (ALKYLIMINO) 1,2,3,4 TETRAHYDRO 6H PYRAZINO[2,1 B]QUINAZOLIN 6 ONE DERIVATIVE; 2 3 (ALKYLIMINO) 1,2,3,4,7,8,9,10 OCTAHYDRO 6H[1]BENZOTHIENO[2,3 D]PYRAZINO[2,1 A]PYRIMIDIN 6 ONE DERIVATIVE; 2 3 METHYL 1,2 DIHYDRO 6H PYRAZINO[2,1 B]QUINAZOLIN 6 ONE DERIVATIVE; 8 2,3,7 TRIMETHYL 8,9 DIHYDRO 4H PYRAZINO[1,2 A]THIENO[2,3 D]PYRIMIDIN 4 ONE DERIVATIVE; CHLOROACETONE; CHLOROACETONITRILE; NITRILE; PYRAZINE DERIVATIVE; PYRAZINO[2,1 A]THIENO[3,2 D]PYRIMIDINE DERIVATIVE; PYRAZINO[2,1 B]QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 34249774555     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-966025     Document Type: Article

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