Homologous desensitization of signalling by the alpha (α) isoform of the human thromboxane A2 receptor: A specific role for nitric oxide signalling

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1773, Issue 6, 2007, Pages 970-989

  Kelley Hickie, Leanne P ^a   O'Keeffe, Martina B ^a   Reid, Helen M ^a   Kinsella, B Therese ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Alpha; Desensitization; G protein coupled receptor; Nitric oxide; Phosphorylation; Thromboxane receptor

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 6 ANILINO 5,8 QUINOLINEQUINONE; CALCIUM; CYCLIC GMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; INOSITOL 1,4,5 TRISPHOSPHATE; KT 5823; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN KINASE C; SERINE; THREONINE; THROMBOXANE A2 RECEPTOR;

ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; DESENSITIZATION; DRUG MECHANISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; BETA-ADRENERGIC RECEPTOR KINASE; CALCIUM SIGNALING; CELL LINE; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; HEMOSTASIS; HUMANS; INDOLES; INOSITOL 1,4,5-TRISPHOSPHATE; MALEIMIDES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PLATELET ACTIVATION; PROTEIN ISOFORMS; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; THROMBOXANE A2; VASOCONSTRICTOR AGENTS;

EID: 34249746416     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2007.03.012     Document Type: Article

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