Biofilm formation by Propionibacterium acnes is associated with increased resistance to antimicrobial agents and increased production of putative virulence factors

Research in Microbiology

Volumn 158, Issue 4, 2007, Pages 386-392

  Coenye, Tom ^a   Peeters, Elke ^a   Nelis, Hans J ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Acne vulgaris; Antibiotic resistance; Biofilm; Lipase; Propionibacterium acnes; Quorum sensing

Indexed keywords

ANTIINFECTIVE AGENT; AZELAIC ACID; BENZOYL PEROXIDE; CLINDAMYCIN; DOXYCYCLINE; ERYTHROMYCIN; MINOCYCLINE; OXYTETRACYCLINE; S RIBOSYLHOMOCYSTEINASE; SALICYLIC ACID; TRIACYLGLYCEROL LIPASE; TRICLOSAN; VIRULENCE FACTOR;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL; BACTERIAL STRAIN; BIOFILM; CONTROLLED STUDY; CORRELATION ANALYSIS; MICROTITER PLATE ASSAY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; QUORUM SENSING; SESSILE SPECIES;

ACNE VULGARIS; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BIOFILMS; CARBON-SULFUR LYASES; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; HOMOSERINE; HUMANS; LACTONES; LIPASE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PROPIONIBACTERIUM ACNES; QUORUM SENSING; VIRULENCE FACTORS;

PROPIONIBACTERIUM ACNES;

EID: 34249716830     PISSN: 09232508     EISSN: 17697123     Source Type: Journal    
DOI: 10.1016/j.resmic.2007.02.001     Document Type: Article

References (46)

1. Bojar R.A., Cunliffe W.J., and Holland K.T. Disruption of the transmembrane pH gradient - a possible mechanism for the antibacterial action of azelaic acid in Propionibacterium acnes and Staphylococcus aureus. J. Antimicrob. Chemother. 34 (1994) 321-330
2. Bruggemann H., Henne A., Hoster F., Liesegang H., Wiezer A., Strittmatter A., Hujer S., Durre P., and Gottschalk G. The complete genome sequence of Propionibacterium acnes, a commensal of human skin. Science 305 (2004) 671-673
3. Burkhart C.N., and Burkhart C.G. Antibiotic-resistant Propionibacterium acnes may not be the major issue clinically or microbiologically in acne. Br. J. Dermatol. 148 (2003) 363-384
4. Burkhart C.N., and Burkhart C.G. Microbiology's principle of biofilms as a major factor in the pathogenesis of acne vulgaris. Int. J. Dermatol. 42 (2003) 925-927
5. Burkhart C.N., and Burkhart C.G. Genome sequence of Propionibacterium acnes reveals immunogenic and surface-associated genes confirming existence of the acne biofilm. Int. J. Dermatol. 45 (2006) 872
6. Chen X., and Stewart P.S. Biofilm removal caused by chemical treatments. Wat. Res. 34 (2000) 4229-4233
7. Coates P., Vyakrnam S., Eady E.A., Jones C.E., Cove J.H., and Cunliffe W.J. Prevalence of antibiotic-resistant propionibacteria on the skin of acne patients: 10-year surveillance data and snapshot distribution study. Br. J. Dermatol. 146 (2002) 840-848
8. Cooper A.J. Systematic review of Propionibacterium acnes resistance to systemic antibiotics. Med. J. Austr. 169 (1998) 259-261
9. Donlan R.M. Biofilm formation: a clinically relevant microbiological process. Clin. Infect. Dis. 33 (2001) 1387-1392
10. Donlan R.M., and Costerton J.W. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin. Microbiol. Rev. 15 (2002) 167-193
11. Dreno B. Topical antibacterial therapy for acne vulgaris. Drugs 64 (2004) 2389-2397
12. Eady E.A., Cove J.H., and Layton A.M. Is antibiotic resistance in cutaneous propionibacteria clinically relevant?. Am. J. Clin. Dermatol. 4 (2003) 813-831
13. Gazenko S.V., Reponen T.A., Grinshpun S.A., and Willeke K. Analysis of airborne actinomycete spores with fluorogenic substrates. Appl. Env. Microbiol. 64 (1998) 4410-4415
14. Gollnick H. Current concepts of the pathogenesis of acne: implications for drug treatment. Drugs 63 (2003) 1579-1596
15. Gribbon E.M., Cunliffe W.J., and Holland K.T. Interaction of Propionibacterium acnes with skin lipids in vitro. J. Gen. Microbiol. 139 (1993) 1745-1751
16. Henke J.M., and Bassler B.L. Three parallel quorum-sensing systems regulate gene expression in Vibrio harveyi. J. Bacteriol. 186 (2004) 6902-6914
17. Hoeffler U. Enzymatic and hemolytic properties of Propionibacterium acnes and related bacteria. J. Clin. Microbiol. 6 (1977) 555-558
18. Jappe U. Pathological mechanisms of acne with special emphasis on Propionibacterium acnes and related therapy. Acta Derm. Venereol. 83 (2003) 241-248
19. Kabongo Muamba M.L. Exoenzymes of Propionibacterium acnes. Can. J. Microbiol. 28 (1982) 758-761
20. Keren I., Kaldalu N., Spoering A., Wang Y., and Lewis K. Persister cells and tolerance to antimicrobials. FEMS Microbiol. Lett. 230 (2004) 13-18
21. Krautheim A., and Gollnick H.P.M. Acne: topical treatment. Clin. Dermatol. 22 (2004) 398-407
22. Lee W.L., Shalita A.R., Suntharalingam K., and Fikrig S.M. Neutrophil chemotaxis by Propionibacterium acnes lipase and its inhibition. Infect. Immun. 35 (1982) 71-78
23. Lee T.W., Kim J.C., and Hwang S.J. Hydrogel patches containing triclosan for acne treatment. Eur. J. Pharm. Biopharm. 56 (2003) 407-412
24. Lewis K. Riddle of biofilm resistance. Antimicrob. Ag. Chemother. 45 (2001) 999-1007
25. Muller E., Al-Attar J., Wolff A.G., and Farber B.F. Mechanisms of salicylate-mediated inhibition of biofilm in Staphylococcus epidermidis. J. Infect. Dis. 117 (1998) 501-503
26. Nicodème M., Grill J.P., Humbert G., and Gaillard J.L. Extracellular protease activity of different Pseudomonas strains: dependence of proteolytic activity on culture conditions. J. Appl. Microbiol. 99 (2005) 641-648
27. Nord C.E., and Oprica C. Antibiotic resistance in Propionibacterium acnes: microbiological and clinical aspects. Anaerobe 12 (2006) 207-210
28. Oprica C., Nord C.E., and on behalf of the ESCMID Study Group on Antimicrobial Resistance in Anaerobic Bacteria. European surveillance study on the antibiotic susceptibility of Propionibacterium acnes. Clin. Microbiol. Infect. 11 (2004) 204-213
29. Parsek M.R., and Singh P.K. Bacterial biofilms: an emerging link to disease pathogenesis. Annu. Rev. Microbiol. 57 (2003) 677-701
30. Ramage G., Tunney M.M., Patrick S., Gorman S.P., and Nixon J.R. Formation of Propionibacterium acnes biofilms on orthopaedic biomaterials and their susceptibility to antimicrobials. Biomaterials 24 (2003) 3221-3227
31. Ross J.I., Snelling A.M., Carnegie E., Coates P., Cunliffe W.J., Bettoli V., Katsambas A., Galvan Perez del Pulgar J.I., Rollman O., Török L., Eady E.A., and Cove J.H. Antibiotic-resistant acne: lessons from Europe. Br. J. Dermatol. 148 (2003) 467-478
32. Russell A.D. Whither triclosan?. J. Antimicrob. Chemother. 53 (2004) 693-695
33. Siboo R., Al-Joburi W., Gornitsky M., and Chan E.C.S. Synthesis and secretion of phospholipase C by oral spirochetes. J. Clin. Microbiol. 27 (1989) 568-570
34. Simonart T., and Dramaix M. Treatment of acne with topical antibiotics: lessons from clinical studies. Br. J. Dermatol. 153 (2005) 395-403
35. Spizek J., and Rezanka T. Lincomycin, clindamycin and their applications. Appl. Microbiol. Biotechnol. 64 (2004) 455-464
36. Stepanovic S., Vukovic D., Dakic L., Savic B., and Svabic-Vlahovic M. A modified microtiter-plate test for quantification of staphylococcal biofilm formation. J. Microbiol. Methods 40 (2000) 175-179
37. Stewart P.S., and Costerton J.W. Antibiotic resistance of bacteria in biofilms. Lancet 358 (2001) 135-138
38. Sun J., Daniel R., Wagner-Döbler I., and Zeng A.P. Is autoinducer-2 a universal signal for interspecies communication: a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathways. BMC Evol. Biol. 4 (2004) 36
39. Takemura N., Noiri Y., Ehara A., Kawahara T., Noguchi N., and Ebisu S. Single species biofilm-forming ability of root canal isolates on gutta-percha points. Eur. J. Oral. Sci. 112 (2004) 523-529
40. Tan H.H. Topical antibacterial treatments for acne vulgaris. Am. J. Clin. Dermatol. 5 (2004) 79-84
41. Taylor G.A., and Shalita A.R. Benzoyl peroxide-based combination therapies for acne vulgaris. Am. J. Clin. Dermatol. 5 (2004) 261-265
42. Thiboutot D. New treatments and therapeutic strategies for acne. Arch. Fam. Med. 9 (2000) 179-187
43. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G. The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 24 (1997) 4876-4882
44. Webster G. Combination azelaic acid therapy for acne vulgaris. J. Am. Acad. Dermatol. 43 (2000) S47-S50
45. Webster G. Acne vulgaris. Brit. Med. J. 325 (2002) 475-478
46. Zhu J., Miller M.B., Vance R.E., Dziejman M., Bassler B.L., and Mekalanos J.J. Quorum-sensing regulators control virulence gene expression in Vibrio cholerae. Proc. Natl. Acad. Sci. USA. 99 (2002) 3129-3134