Multicomponent T2 analysis of dithiocarbamate-mediated peripheral nerve demyelination

NeuroToxicology

Volumn 28, Issue 3, 2007, Pages 645-654

  Valentine, Holly L ^a   Does, Mark D ^b,c   Marshall, Vivian ^c   Tonkin, Elizabeth G ^a   Valentine, William M ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

Copper; Demyelination; Dithiocarbamates; Multicomponent T2 analysis; Neurotoxicity

Indexed keywords

COPPER; DITHIOCARBAMIC ACID DERIVATIVE; N,N DIETHYLDITHIOCARBAMIC ACID DERIVATIVE; PYRROLIDINE DITHIOCARBAMATE; UNCLASSIFIED DRUG; COLORING AGENT; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; THIOCARBAMIC ACID DERIVATIVE; TOLONIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC EMISSION SPECTROMETRY; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEMYELINATION; EDEMA; HISTOPATHOLOGY; MALE; NERVE FIBER DEGENERATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PERIPHERAL NERVE; PRIORITY JOURNAL; RAT; SCIATIC NERVE; ANIMAL; ATOMIC ABSORPTION SPECTROMETRY; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DEMYELINATING DISEASE; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA; RATTUS;

ANIMALS; COLORING AGENTS; COPPER; DEMYELINATING DISEASES; INJECTIONS, INTRAPERITONEAL; MAGNETIC RESONANCE IMAGING; MALE; PERIPHERAL NERVES; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SPECTROPHOTOMETRY, ATOMIC; THIOCARBAMATES; TOLONIUM CHLORIDE;

EID: 34249660020     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2007.01.009     Document Type: Article

References (52)

1. Alexeeff G.V., Shusterman D.J., Howd R.A., and Jackson R.J. Dose-response assessment of airborne methyl isothiocyanate (MITC) following a metam sodium spill. Risk Anal 14 (1994) 191-198
2. Bendszus M., Wessig C., Solymosi L., Reiners K., and Koltzenburg M. MRI of peripheral nerve degeneration and regeneration: correlation with electrophysiology and histology. Exp Neurol 188 (2004) 171-177
3. Berry J.M., Jacobs C., Sikic B., Halsey J., and Borch R.F. Modification of cisplatin toxicity with diethyldithiocarbamate. J Clin Oncol 8 (1990) 1585-1590
4. Blamire A.M., Rowe J.G., Styles P., and McDonald B. Optimising imaging parameters for post mortem MR imaging of the human brain. Acta Radiol 40 (1999) 593-597
5. Brewer C. Long-term, high-dose disulfiram in the treatment of alcohol abuse. Br J Psychiatry 163 (1993) 687-689
6. Brown D.R., and Sassoon J. Copper-dependent functions for the prion protein. Mol Biotechnol 22 (2002) 165-178
7. Calviello G., Filippi G.M., Toesca A., Palozza P., Maggiano N., Nicuolo F.D., Serini S., Azzena G.B., and Galeotti T. Repeated exposure to pyrrolidine-dithiocarbamate induces peripheral nerve alterations in rats. Toxicol Lett 158 (2005) 61-71
8. Campadelli P., Gangai C., and Pasquale F. Automated morphometric analysis in peripheral neuropathies. Comp Biol Med 29 (1999) 147-156
9. Carvlin J.J., Asato R., Hackney D.B., Kassab E., and Joseph P.M. High-resolution MR of the spinal cord in humans and rats. Am J Neuroradiol 10 (1989) 13-17
10. Chen S.H., Liu S.H., Liang Y.C., Lin J.K., and Lin-Shiau S.Y. Death signaling pathway induced by pyrrolidine dithiocarbamate-Cu(2+) complex in the cultured rat cortical astrocytes. Glia 31 (2000) 249-261
11. Child G.P., Osinski W., Bennett R.E., and Davidoff E. Therapeutic results and clinical manifestations following the use of tetraethylthiuram disulfide (antabuse). Am J Psychiatry 107 (1951) 774-780
12. Cristofori P, Terron A, Marella M, Moretti U, Pasqualicchio M, Velo GP, et al. Copper supplementation in the rat: preliminary observations on the clinical, hematological and histopathological profile. Agents Actions; 1992 [Spec. No.: C118-20].
13. Delmaestro E., and Trombetta L.D. The effects of disulfiram on the hippocampus and cerebellum of the rat brain: a study on oxidative stress. Toxicol Lett 75 (1995) 235-243
14. 2 relaxation of peripheral nerve measured in vivo. Magn Reson Imag 13 (1995) 575-580
15. 2 relaxation in degenerating peripheral nerve. Magn Reson Med 35 (1996) 207-213
16. Edington N., and Howell J.M. The neurotoxicity of sodium diethyldithiocarbamate in the rabbit. Acta Neuropathol 12 (1969) 339-347
17. Eneanya D.I., Bianchine J.R., Duran D.O., and Andresen Gd. The actions and metabolic fate of disulfiram. Ann Rev Pharmacol Toxicol 21 (1981) 575-596
18. Everling W.E., Haywood S., Elmes M.E., Jasani B., and Trafford J. Histochemical and immunocytochemical evaluation of copper and metallothionein in the liver and kidney of copper-loaded rats. J Pathol 160 (1990) 305-312
19. Fuentealba I.C., Mullins J.E., Aburto E.M., Lau J.C., and Cherian G.M. Effect of age and sex on liver damage due to excess dietary copper in Fischer 344 rats. J Toxicol Clin Toxicol 38 (2000) 709-717
20. Guena S., Tos P., Guglielmone R., Battiston B., and Giacobini-Robecchi M. Methodological issues in size estimation of myelinated nerve fibers in peripheral nerves. Anat Embryol 204 (2001) 1-10
21. Johnson D.J., Graham D.G., Amarnath V., Amarnath K., and Valentine W.M. Release of carbon disulfide is a contributing mechanism in the axonopathy produced by N,N-diethyldithiocarbamate. Toxicol Appl Pharmacol 148 (1998) 288-296
22. Kennedy W., Wendelshafer-Crabb G., Polydefkis M., and McArthur J. Pathology and quantitation of cutaneous innervation. In: Dyck P., and Thomas P. (Eds). Peripheral neuropathy (2005), Elsevier Saunders, Philadelphia 876-879
23. Kreutzer R.A., Hewitt D.J., and Draper W.M. An epidemiological assessment of the cantara metam sodium spill: acute health effects of methylisothiocyanate exposure. Adv Chem Ser 241 (1994) 209-230
24. Lang J.M., Touraine J.L., Trepo C., Choutet P., Kirstetter M., Falkenrodt A., Herviou L., Livrozet J.M., Retornaz G., and Touraine F. Randomised, double-blind, placebo-controlled trial of ditiocarb sodium ('Imuthiol') in human immunodeficiency virus infection. Lancet 2 (1988) 702-706
25. Menon R.S., Rusinko M.S., and Allen P.S. Proton relaxation studies of water compartmentalization in a model neurological system. Magn Reson Med 28 (1992) 264-274
26. Milanino R., Marrella M., Crivellente F., Benoni G., and Cuzzolin L. Nutritional supplementation with copper in the rat. I. Effects on adjuvant arthritis development and on some in vivo- and ex vivo-markers of blood neutrophils. Inflamm Res 49 (2000) 214-223
27. Multhaup G., Dieter H.H., Beyrreuther K., and Bayer T. Role of copper and other transition metal ions in the pathogenesis of Parkinson's disease, prion diseases, familial amyotrophic lateral sclerosis, and Alzheimer's disease. In: Massaro E. (Ed). Handbook of copper pharmacology and toxicology (2002), Humana Press, Totowa 297-317
28. Orrenius S., Nobel C.S., van den Dobbelsteen D.J., Burkitt M.J., and Slater A.F. Dithiocarbamates and the redox regulation of cell death. Biochem Soc Trans 24 (1996) 1032-1038
29. Peled S., Cory D.G., Raymond S.A., Kirschner D.A., and Jolesz F.A. Water diffusion, T(2), and compartmentation in frog sciatic nerve. Magn Reson Med 42 (1999) 911-918
30. Perry V.H., Brown M.C., and Gordon S. The macrophage response to central and peripheral nerve injury. J Exp Med 165 (1987) 1218-1223
31. Pun T.W., Odrobina E., Xu Q.G., Lam T.Y., Munro C.A., Midha R., and Stanisz G.J. Histological and magnetic resonance analysis of sciatic nerves in the tellurium model of neuropathy. J Periph Nerv Syst 10 (2005) 38-46
32. Rae T.D., Schmidt P.J., Pufahl F.A., Culotta V.C., and O'Halloran T.V. Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase. Science 284 (1999) 805-808
33. Romero E., Cuisenaire O., Denef J.F., Delbeke J., Macq B., and Veraart C. Automatic morphometry of nerve histological sections. J Neurosci Methods 97 (2000) 111-122
34. Rotilio G., Ciriolo M.R., Carri M.T., and Rossi L. Disturbances of copper homeostasis and brain function. In: Massaro E. (Ed). Handbook of copper pharmacology and toxicology (2002), Humana Press, Totowa 277-296
35. Santoro V., Trombetta G., Leonardi L., and Messina C. A computer-assisted automatic method for myelinated nerve fiber morphometry. Acta Neurol Scand 85 (1992) 18-22
36. Stanisz G.J., Webb S., Munro C.A., Pun T., and Midha R. MR properties of excised neural tissue following experimentally induced inflammation. Magn Reson Med 51 (2004) 473-479
37. Stoll G., Trapp B.D., and Griffin J.W. Macrophage function during wallerian degeneration of rat optic nerve: clearance of degenerating myelin and la expression. J Neurosci 9 (1989) 2327-2335
38. Strausak D., Mercer J.F., Dieter H.H., Stremmel W., and Multhaup G. Copper in disorders with neurological symptoms: Alzheimer's, Menkes, and Wilson diseases. Brain Res Bull 55 (2001) 175-185
39. Thelwall P.E., Shepherd T.M., Stanisz G.J., and Blackband S.J. Effects of temperature and aldehyde fixation on tissue water diffusion properties, studied in an erythrocyte ghost tissue model. Magn Reson Med 56 (2006) 282-289
40. Titelbaum D.S., Frazier J.L., Grossman R.I., Joseph P.M., Yu L.T., Kassab E.A., Hickey W.F., LaRossa D., and Brown M.J. Wallerian degeneration and inflammation in rat peripheral nerve detected by in vivo MR imaging. Am J Neuroradiol 10 (1989) 741-746
41. Tonkin E.G., Erve J.C., and Valentine W.M. Disulfiram produces a non-carbon disulfide-dependent schwannopathy in the rat. J Neuropathol Exp Neurol 59 (2000) 786-797
42. Tonkin E.G., Valentine H.L., Milatovic D.M., and Valentine W.M. N,N-Diethyldithiocarbamate produces copper accumulation, lipid peroxidation, and myelin injury in rat peripheral nerve. Toxicol Sci 81 (2004) 160-171
43. Tovi M., and Ericsson A. Measurements of T1 and T2 over time in formalin-fixed human whole-brain specimens. Acta Radiol 33 (1992) 400-404
44. Valentine H.L., Amarnath K., Amarnath V., and Valentine W.M. Dietary copper enhances the peripheral myelinopathy produced by oral pyrrolidine dithiocarbamate. Toxicol Sci 89 (2006) 485-494
45. Valentine W.M., Amarnath V., Amarnath K., Rimmele F., and Graham D.G. Carbon disulfide mediated protein cross-linking by N,N-diethyldithiocarbamate. Chem Res Toxicol 8 (1995) 96-102
46. Vasilescu V., Katon E., Simplaceanu V., and Demco D. Water compartments in the myelinated nerve. III. Pulsed NMR results. Experientia 34 (1978) 1443-1444
47. Vettorazzi G., Almeida W.F., Burin G.J., Jaeger R.B., Puga F.R., Rahde A.F., Reyes F.G., and Schvartsman S. International safety assessment of pesticides: dithiocarbamate pesticides, ETU, and PTU-a review and update. Teratog Carcinog Mutagen 15 (1995) 313-337
48. Webb S., Munro C.A., Midha R., and Stanisz G.J. Is multicomponent T2 a good measure of myelin content in peripheral nerve?. Magn Reson Med 49 (2003) 638-645
49. Whittall K.P., and MacKay A.L. Quantitative interpretation of NMR relaxation data. J Magn Reson 84 (1989) 134-152
50. WHO dithiocarbamate pesticides, ethylenethiourea, and propylenethiourea: a general introduction 1988;78:11-68.
51. Wilson A., and Trombetta L.D. The protective effects of zinc on diethyldithiocarbamate cytotoxicity on rat astrocytes in vitro. Toxicol Lett 105 (1999) 129-140
52. Yong-Hing C.J., Obenaus A., Stryker R., Tong K., and Sarty G.E. Magnetic resonance imaging and mathematical modeling of progressive formalin fixation of the human brain. Magn Reson Med 54 (2005) 324-332