Dietary copper enhances the peripheral myelinopathy produced by oral pyrrolidine dithiocarbamate

Toxicological Sciences

Volumn 89, Issue 2, 2006, Pages 485-494

  Valentine, Holly L ^a   Amarnath, Kalyani ^a   Amarnath, Venkataraman ^a   Valentine, William M ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Copper; Demyelination; Dithiocarbamate; Myelin; Peripheral neuropathy; Sodium pyrrolidine dithiocarbamate

Indexed keywords

ACID; ALIPHATIC AMINE; CARBONYL DERIVATIVE; COPPER; CYSTEINE DERIVATIVE; DIETHYLDITHIOCARBAMIC ACID; DITHIOCARBAMIC ACID DERIVATIVE; DRINKING WATER; GLOBIN; MYELIN; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC EMISSION SPECTROMETRY; BRAIN LEVEL; CONTROLLED STUDY; DEMYELINATING NEUROPATHY; DIET SUPPLEMENTATION; ELECTRON MICROSCOPY; EXPOSURE; HOMEOSTASIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NERVE FIBER DEGENERATION; NERVE INJURY; NERVE LESION; NEUROTOXICITY; NONHUMAN; PERIPHERAL NERVE; PERIPHERAL NEUROPATHY; RAT; RAT STRAIN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCIATIC NERVE;

ADMINISTRATION, ORAL; ANIMALS; CHROMATOGRAPHY, LIQUID; COPPER; DEMYELINATING DISEASES; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENVIRONMENTAL POLLUTANTS; GLOBINS; MALE; MASS SPECTROMETRY; MICROSCOPY, ELECTRON; PERIPHERAL NERVES; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; THIOCARBAMATES; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 31144443476     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfj047     Document Type: Article

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