Cysteine at position 217 in the intracellular loop 1 plays a critical role in human PTH receptor type 1 membrane translocation and function

Journal of Bone and Mineral Research

Volumn 22, Issue 4, 2007, Pages 609-616

  Thomas, Beena E ^a   Wittelsberger, Angela ^a   Woznica, Iwona ^a   Hsieh, Mo Ying ^a   Monaghan, Paul ^a   Lee, Byung Kwon ^b   Rosenblatt, Michael ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

Author keywords

C L mutation; Intracellular loop; PTH receptor type 1; Site directed mutagenesis; Total and surface receptor expression

Indexed keywords

ADENYLATE CYCLASE; BLOOD CLOTTING FACTOR 10A; CELL SURFACE PROTEIN; CYSTEINE; MEMBRANE PROTEIN; MESSENGER RNA; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RECEPTOR 1; PRIMER DNA; PTHR1 PROTEIN, HUMAN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE MICROSCOPY; LIGAND BINDING; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HUMAN; IN VITRO STUDY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; CYSTEINE; DNA PRIMERS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTOR, PARATHYROID HORMONE, TYPE 1; RECOMBINANT PROTEINS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION;

EID: 34249657490     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.070101     Document Type: Article

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