A gene cluster of the ochratoxin A biosynthetic genes in Penicillium

Mycotoxin Research

Volumn 22, Issue 2, 2006, Pages 134-141

  Geisen, R ^a   Schmidt Heydt, M ^a   Karolewiez, A ^a  

^a FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

Author keywords

Biosynthetic genes; Ochratoxin A; Penicillium nalgiovense; Penicillium nordicum; Penicillium verrucosum

Indexed keywords

EID: 34249304349     PISSN: 01787888     EISSN: 18671632     Source Type: Journal    
DOI: 10.1007/BF02956777     Document Type: Conference Paper

References (18)

1. Sage M, Krivobok S, Delbos E, Seigle-Murandi F, Creppy EE (2002) Fungal flora and ochratoxin A production in grapes and musts from France. J Agric Food Chem 50:1306-1311
2. Thirumala-Devi K, Mayo MA, Reddy G, Emmanuel KE, Larondelle Y, Reddy DVR (2001) Occurrence of ochratoxin A in black pepper, coriander, ginger and turmeric in India. Food Addit Contam 18:830-835
3. Joosten HMLJ, Goetz J, Pittet A, Schellenberg M, Bucheli P (2001) Production of ochratoxin A by Aspergillus carbonarius on coffee cherries. Int J Food Microbiol 65:39-44
4. Larsen TO, Svendsen A, Smedsgaard J (2001) Biochemical characterization of ochratoxin A-producing strains of the genus Penicillium. Appl Environ Microbiol 67:3630-3635
5. Lund F, Frisvad JC (2003) Penicillium verrucosum in wheat and barley indicates presence of ochratoxin A. J Appl Microbiol 95:1117-1123
6. Bogs C, Battilani P, Geisen R (2006) Development of a molecular detection and differentiation system for ochratoxin A producing Penicillium species and its application to analyse the occurrence of P.nordicum in cured meats. Int J Food Microbiol 107:39-47
7. O'Callaghan J, Caddick MX, Dobson ADW (2003) A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus. Microbiology 149:3485-3491
8. Karolewiez A, Geisen R (2005) Cloning a part of the ochratoxin A biosynthetic gene cluster of Penicillmm nordicum and characterization of the ochratoxin polyketide synthase gene. System Appl Microbiol 28:588-595
9. Geisen R (2004) Molecular monitoring of environmental conditions influencing the induction of ochratoxin A biosynthetic genes in Penicillium nordicum. Mol Nutr Food Res 48:532-540
10. Färber P, Geisen R (2004) Analysis of differentially-expressed ochratoxin A biosynthesis genes of Penicillium nordicum. European J Plant Pathol 110:661-669
11. Sambrook J, Russel DW (2001) Molecular Cloning. 3, Cold Spring Harbour Laboratory Press, New York
12. Noe B, Hagenbuch B, Stieger B, Meier PJ (1997) Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain. Proc Natl Acad Sci USA 94:10346-10350
13. Walton JD (2000) Horizontal gene transfer and the evolution of secondary metabolite gene clusters in fungi: an hypothesis. Fungal Genet Biol 30, 167-171
14. Ehrlich KC, Yu J, Cotty PJ (2005) Aflatoxin biosynthesis gene clusters and flanking regions. J Appl Microbiol 99:518-527
15. Simons BH, Barnett P, Vollenbroek EGM, Dekker HL, Muijsers AO, Messerschmidt A, Wever R (1995) Primary structure and characterization of the vanadium chloroperoxidase from the fungus Curvularia inaegualis. Eur J Biochem 229:566-574
16. Shimizu T, Kinoshita H, Ishihara S, Sakai K, Nagai S, Nihira T (2005) Polyketide synthase gene responsible for citrinin biosynthesis in Monascus purpureus. Appl Environ Microbiol 71:3453-3457
17. Höhler D (1998) Ochratoxin A in food and feed: occurence, legislation and mode of action. Z Ernahrungswiss 37:2-12
18. Stergiopoulos I, Zwiers LH, De Waard MA (2002) Secretion of natural and synthetic toxic compounds from filamentous fungi by membrane transporters of the ATP-binding cassette and major facilitator superfamily. Eur J Plant Pathol 108:719-734