Substantial shared genetic influences on schizophrenia and event-related potentials

American Journal of Psychiatry

Volumn 164, Issue 5, 2007, Pages 804-812

  Hall, Mei Hua ^b   Rijsdijk, Frühling ^b   Picchioni, Marco ^b   Schulze, Katja ^b   Ettinger, Ulrich ^b   Toulopoulou, Timothea ^b   Bramon, Elvira ^b   Murray, Robin M ^b   Sham, Pak ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMPLITUDE MODULATION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; EVENT RELATED POTENTIAL; FEMALE; GENETIC CORRELATION; HEREDITY; HUMAN; MALE; MISMATCH NEGATIVITY; PHENOTYPE; PRIORITY JOURNAL; SCHIZOPHRENIA; TWINS; ZYGOSITY;

EID: 34249296342     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.2007.164.5.804     Document Type: Article

References (48)

1. Gottesman II, Gould TD: The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003; 160:636-645
2. Freedman R, Adler LE, Leonard S: Alternative phenotypes for the complex genetics of schizophrenia. Biol Psychiatry 1999; 45:551-558
3. Bramon E, McDonald C, Croft RJ, Landau S, Filbey F, Gruzelier JH, Sham PC, Frangou S, Murray RM: Is the P300 wave an endophenotype for schizophrenia? a meta-analysis and a family study. Neuroimage 2005; 27:960-968
4. Callicott JH, Egan MF, Mattay VS, Bertolino A, Bone AD, Verchinksi B, Weinberger DR: Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia. Am J Psychiatry 2003; 160:709-719; correction, 2004; 161:1145
5. Blackwood DH, St Clair DM, Muir WJ, Duffy JC: Auditory P300 and eye tracking dysfunction in schizophrenic pedigrees. Arch Gen Psychiatry 1991; 48:899-909
6. Ettinger U, Kumari V, Crawford TJ, Corr PJ, Das M, Zachariah E, Hughes C, Sumich AL, Rabe-Hesketh S, Sharma T: Smooth pursuit and antisaccade eye movements in siblings discordant for schizophrenia. J Psychiatr Res 2004; 38:177-184
7. Clementz BA, Geyer MA, Braff DL: Poor P50 suppression among schizophrenia patients and their first-degree biological relatives. Am J Psychiatry 1998; 155:1691-1694
8. McDonald C, Grech A, Toulopoulou T, Schulze K, Chapple B, Sham P, Walshe M, Sharma T, Sigmundsson T, Chitnis X, Murray RM: Brain volumes in familial and non-familial schizophrenic probands and their unaffected relatives. Am J Med Genet 2002; 114:616-625
9. Seidman LJ, Faraone SV, Goldstein JM, Kremen WS, Horton NJ, Makris N, Toomey R, Kennedy D, Caviness VS, Tsuang MT: Left hippocampal volume as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric study of nonpsychotic first-degree relatives. Arch Gen Psychiatry 2002; 59:839-849
10. Boomsma D, Busjahn A, Peltonen L: Classical twin studies and beyond. Nat Rev Genet 2002; 3:872-882
11. Kendler KS: Psychiatric genetics: a methodologic critique. Am J Psychiatry 2005; 162:3-11
12. Martin N, Boomsma D, Machin G: A twin-pronged attack on complex traits. Nat Genet 1997; 17:387-392
13. Rijsdijk FV, van Haren NE, Picchioni MM, McDonald C, Toulopoulou T, Pol HE, Kahn RS, Murray R, Sham PC: Brain MRI abnormalities in schizophrenia: same genes or same environment? Psychol Med 2005; 35:1399-1409
14. Koenen KC, Hitsman B, Lyons MJ, Niaura R, McCaffery J, Goldberg J, Eisen SA, True W, Tsuang M: A twin registry study of the relationship between posttraumatic stress disorder and nicotine dependence in men. Arch Gen Psychiatry 2005; 62:1258-1265
15. Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ: Major depression and generalized anxiety disorder: same genes, (partly) different environments? Arch Gen Psychiatry 1992; 49:716-722
16. Neale MC, Kendler KS: Models of comorbidity for multifactorial disorders. Am J Hum Genet 1995; 57:935-953
17. van Erp TG, Saleh PA, Huttunen M, Lonnqvist J, Kaprio J, Salonen O, Valanne L, Poutanen VP, Standertskjold-Nordenstam CG, Cannon TD: Hippocampal volumes in schizophrenic twins. Arch Gen Psychiatry 2004; 61:346-353
18. van Haren NEM, Picchioni MM, McDonald C, Marshall N, Davis N, Ribchester T, Hulshoff Pol HE, Sharma T, Sham P, Kahn RS, Murray R: A controlled study of brain structure in monozygotic twins concordant and discordant for schizophrenia. Biol Psychiatry 2004; 56:454-461
19. Baare WF, van Oel CJ, Hulshoff Pol HE, Schnack HG, Durston S, Sitskoorn MM, Kahn RS: Volumes of brain structures in twins discordant for schizophrenia. Arch Gen Psychiatry 2001; 58: 33-40
20. Goldberg TE, Ragland JD, Torrey EF, Gold JM, Bigelow LB, Weinberger DR: Neuropsychological assessment of monozygotic twins discordant for schizophrenia. Arch Gen Psychiatry 1990; 47:1066-1072
21. Cannon TD, Huttunen MO, Lonnqvist J, Tuulio-Henriksson A, Pirkola T, Glahn D, Finkelstein J, Hietanen M, Kaprio J, Koskenvuo M: The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia. Am J Hum Genet 2000; 67: 369-382
22. Bramon E, Rabe-Hesketh S, Sham P, Murray RM, Frangou S: Meta-analysis of the P300 and P50 waveforms in schizophrenia. Schizophr Res 2004; 70:315-329
23. Michie PT, Innes-Brown H, Todd J, Jablensky AV: Duration mismatch negativity in biological relatives of patients with schizophrenia spectrum disorders. Biol Psychiatry 2002; 52:749-758
24. Weisbrod M, Hill H, Niethammer R, Sauer H: Genetic influence on auditory information processing in schizophrenia: P300 in monozygotic twins. Biol Psychiatry 1999; 46:721-725
25. Picchioni MM, Toulopoulou T, Landau S, Davies N, Ribchester T, Murray RM: Neurological abnormalities in schizophrenic twins. Biol Psychiatry 2006; 59:341-348
26. Belmaker R, Pollin W, Wyatt RJ, Cohen S: A follow-up of monozygotic twins discordant for schizophrenia. Arch Gen Psychiatry 1974; 30:219-222
27. Hall MH, Schulze K, Rijsdijk F, Picchioni M, Ettinger U, Bramon E, Freedman R, Murray RM, Sham P: Heritability and reliability of P300, P50 and duration mismatch negativity. Behav Genet 2006; 36:845-857; Epub 2006 July 7
28. Adler LE, Hoffer LD, Wiser A, Freedman R: Normalization of auditory physiology by cigarette smoking in schizophrenic patients. Am J Psychiatry 1993; 150:1856-1861
29. Semlitsch HV, Anderer P, Schuster P, Presslich O: A solution for reliable and valid reduction of ocular artifacts, applied to the P300 ERR Psychophysiology 1986; 23:695-703
30. Neale MC, Boker SM, Xie G, Maes HH: Mx: Statistical Modeling, 5th ed. Richmond, Virginia Commonwealth University, Department of Psychiatry, 1999
31. Baare WF, Hulshoff Pol HE, Boomsma Dl, Posthuma D, de Geus EJ, Schnack HG, van Haren NE, van Oel CJ, Kahn RS: Quantitative genetic modeling of variation in human brain morphology. Cereb Cortex 2001; 11:816-824
32. Hall M-H, Schulze K, Bramon E, Murray R, Sham P, Rijsdijk FV: Genetic overlap between P300, P50 and duration mismatch negativity. Am J Med Genet 2006; 141:336-343
33. Falconer DS, Mackay TFC: Introduction to Quantitative Genetics. White Plains, NY, Longman, 1996
34. Sullivan PF, Kendler KS, Neale MC: Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry 2003; 60:1187-1192
35. van Beijsterveldt CE, van Baal GC: Twin and family studies of the human electroencephalogram: a review and a meta-analysis. Biol Psychol 2002; 61:111-138
36. Neale MC, Maes HH: Methodology for Genetic Studies of Twins and Families. Dordrecht, Netherlands, Kluwer Academic, 2004
37. Umbricht D, Krljes S: Mismatch negativity in schizophrenia: a meta-analysis. Schizophr Res 2005; 76:1-23
38. Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, Young DA, Breese CR, Adams C, Patterson D, Adler LE, Kruglyak L, Leonard S, Byerley W: Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci USA 1997; 94:587-592
39. Polich J: Normal variation of P300 from auditory stimuli. Electroencephalogr Clin Neurophysiol 1986; 65:236-240
40. McCarthy G, Donchin E: A metric for thought: a comparison of P300 latency and reaction time. Science 1981; 211:77-80
41. Naatanen R, Paavilainen P, Alho K, Reinikainen K, Sams M: Do event-related potentials reveal the mechanism of the auditory sensory memory in the human brain? Neurosci Lett 1989; 98: 217-221
42. Tiitinen H, May P, Reinikainen K, Naatanen R: Attentive novelty detection in humans is governed by pre-attentive sensory memory. Nature 1994; 372:90-92
43. Salisbury DF, Shenton ME, Griggs CB, Bonner-Jackson A, McCarley RW: Mismatch negativity in chronic schizophrenia and first-episode schizophrenia. Arch Gen Psychiatry 2002; 59:686-694
44. Kendler KS: Twin studies of psychiatric illness: an update. Arch Gen Psychiatry 2001; 58:1005-1014
45. Gonul AS, Suer C, Coburn K, Ozesmi C, Oguz A, Yilmaz A: Effects of olanzapine on auditory P300 in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2003; 27:173-177
46. Umbricht D, Javitt D, Novak G, Bates J, Pollack S, Lieberman J, Kane J: Effects of clozapine on auditory event-related potentials in schizophrenia. Biol Psychiatry 1998; 44:716-725
47. Adler LE, Olincy A, Cawthra EM, McRae KA, Harris JG, Nagamoto HT, Waldo MC, Hall M-H, Bowles A, Woodward L, Ross RG, Freedman R: Varied effects of atypical neuroleptics on P50 auditory gating in schizophrenia patients. Am J Psychiatry 2004; 161:1822-1828
48. Fanous AH, Kendler KS: Genetic heterogeneity, modifier genes, and quantitative phenotypes in psychiatric illness: searching for a framework. Mol Psychiatry 2005; 10:6-13