메뉴 건너뛰기




Volumn 109, Issue 11, 2007, Pages 2299-2307

Loss of heterozygosity and human telomerase reverse transcriptase (hTERT) expression in bronchial mucosa of heavy smokers

Author keywords

Heavy smokers; hTERT mRNA expression; Loss of heterozygosity; Precancerous lesions; Telomerase

Indexed keywords

MESSENGER RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 34249090269     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.22683     Document Type: Article
Times cited : (15)

References (38)
  • 2
  • 3
    • 0034986566 scopus 로고    scopus 로고
    • Molecular genetic abnormalities in premalignant lung lesions: Biological and clinical implications
    • Niklinski J, Niklinska W, Chyczewski L, Becker HD, Pluygers E. Molecular genetic abnormalities in premalignant lung lesions: biological and clinical implications. Eur J Cancer Prev. 2001;10:213-226.
    • (2001) Eur J Cancer Prev , vol.10 , pp. 213-226
    • Niklinski, J.1    Niklinska, W.2    Chyczewski, L.3    Becker, H.D.4    Pluygers, E.5
  • 4
    • 0033590626 scopus 로고    scopus 로고
    • Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma
    • Wistuba, II, Behrens C, Milchgrub S, et al. Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma. Oncogene. 1999;18:643-650.
    • (1999) Oncogene , vol.18 , pp. 643-650
    • Wistuba, I.1    Behrens, C.2    Milchgrub, S.3
  • 5
    • 1842298166 scopus 로고    scopus 로고
    • Clonal genetic alterations in the lungs of current and former smokers
    • Mao L, Lee JS, Kurie JM, et al. Clonal genetic alterations in the lungs of current and former smokers. J Natl Cancer Inst. 1997;89:857-862.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 857-862
    • Mao, L.1    Lee, J.S.2    Kurie, J.M.3
  • 6
    • 0018343201 scopus 로고
    • Changes in bronchial epithelium in relation to cigarette smoking, 1955-1960 vs. 1970-1977
    • Auerbach O, Hammond EC, Garfinkel L. Changes in bronchial epithelium in relation to cigarette smoking, 1955-1960 vs. 1970-1977. N Engl J Med. 1979;300:381-385.
    • (1979) N Engl J Med , vol.300 , pp. 381-385
    • Auerbach, O.1    Hammond, E.C.2    Garfinkel, L.3
  • 8
    • 0037243767 scopus 로고    scopus 로고
    • New techniques for early detection of lung cancer
    • s
    • Sutedja G. New techniques for early detection of lung cancer. Eur Respir J Suppl. 2003;39:57s-66s.
    • (2003) Eur Respir J Suppl , vol.39
    • Sutedja, G.1
  • 9
    • 0030846720 scopus 로고    scopus 로고
    • Molecular damage in the bronchial epithelium of current and former smokers
    • Wistuba, II, Lam S, Behrens C, et al. Molecular damage in the bronchial epithelium of current and former smokers. J Natl Cancer Inst. 1997;89:1366-1373.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1366-1373
    • Wistuba, I.1    Lam, S.2    Behrens, C.3
  • 10
    • 0034669608 scopus 로고    scopus 로고
    • Sporadic colorectal adenocarcinomas with high-frequency microsatellite instability
    • Gafa R, Maestri I, Matteuzzi M, et al. Sporadic colorectal adenocarcinomas with high-frequency microsatellite instability. Cancer. 2000;89:2025-2037.
    • (2000) Cancer , vol.89 , pp. 2025-2037
    • Gafa, R.1    Maestri, I.2    Matteuzzi, M.3
  • 11
    • 0036152444 scopus 로고    scopus 로고
    • Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: A population-based study
    • Stefansson I, Akslen LA, MacDonald N, et al. Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study. Clin Cancer Res. 2002;8:138-143.
    • (2002) Clin Cancer Res , vol.8 , pp. 138-143
    • Stefansson, I.1    Akslen, L.A.2    MacDonald, N.3
  • 12
    • 0141962933 scopus 로고    scopus 로고
    • Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma
    • Geisler JP, Goodheart MJ, Sood AK, Holmes RJ, Hatterman-Zogg MA, Buller RE. Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma. Cancer 2003;98:2199-2206.
    • (2003) Cancer , vol.98 , pp. 2199-2206
    • Geisler, J.P.1    Goodheart, M.J.2    Sood, A.K.3    Holmes, R.J.4    Hatterman-Zogg, M.A.5    Buller, R.E.6
  • 13
    • 3142782440 scopus 로고    scopus 로고
    • Microsatellite instability at chromosome 8p in non-small cell lung cancer is associated with lymph node metastasis and squamous differentiation
    • Woenckhaus M, Stoehr R, Dietmaier W, et al. Microsatellite instability at chromosome 8p in non-small cell lung cancer is associated with lymph node metastasis and squamous differentiation. Int J Oncol. 2003;23:1357-1363.
    • (2003) Int J Oncol , vol.23 , pp. 1357-1363
    • Woenckhaus, M.1    Stoehr, R.2    Dietmaier, W.3
  • 14
    • 0035863510 scopus 로고    scopus 로고
    • Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer
    • Hirao T, Nelson HH, Ashok TD, et al. Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer. Cancer Res. 2001;61:612-615.
    • (2001) Cancer Res , vol.61 , pp. 612-615
    • Hirao, T.1    Nelson, H.H.2    Ashok, T.D.3
  • 15
    • 0033871166 scopus 로고    scopus 로고
    • hMLH1 and hMSH2 expression correlates with allelic imbalance on chromosome 3p in non-small cell lung carcinomas
    • Xinarianos G, Liloglou T, Prime W, et al. hMLH1 and hMSH2 expression correlates with allelic imbalance on chromosome 3p in non-small cell lung carcinomas. Cancer Res. 2000;60:4216-4221.
    • (2000) Cancer Res , vol.60 , pp. 4216-4221
    • Xinarianos, G.1    Liloglou, T.2    Prime, W.3
  • 16
    • 0032533493 scopus 로고    scopus 로고
    • Loss of FHIT function in lung cancer and preinvasive bronchial lesions
    • Sozzi G, Pastorino U, Moiraghi L, et al. Loss of FHIT function in lung cancer and preinvasive bronchial lesions. Cancer Res. 1998;58:5032-5037.
    • (1998) Cancer Res , vol.58 , pp. 5032-5037
    • Sozzi, G.1    Pastorino, U.2    Moiraghi, L.3
  • 18
    • 0029124902 scopus 로고
    • Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: Identification of three independent regions
    • Rasio D, Negrini M, Manenti G, Dragani TA, Croce CM. Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: identification of three independent regions. Cancer Res. 1995;55:3988-3991.
    • (1995) Cancer Res , vol.55 , pp. 3988-3991
    • Rasio, D.1    Negrini, M.2    Manenti, G.3    Dragani, T.A.4    Croce, C.M.5
  • 19
    • 0029936996 scopus 로고    scopus 로고
    • High-density marker analysis of 11p15.5 in non-small cell lung carcinomas reveals allelic deletion of one shared and one distinct region when compared to breast carcinomas
    • Tran YK, Newsham IF. High-density marker analysis of 11p15.5 in non-small cell lung carcinomas reveals allelic deletion of one shared and one distinct region when compared to breast carcinomas. Cancer Res. 1996;56:2916-2921.
    • (1996) Cancer Res , vol.56 , pp. 2916-2921
    • Tran, Y.K.1    Newsham, I.F.2
  • 20
    • 0029075066 scopus 로고
    • Telomeres, telomerase, and immortality
    • Rhyu MS. Telomeres, telomerase, and immortality. J Natl Cancer Inst. 1995;87:884-894.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 884-894
    • Rhyu, M.S.1
  • 21
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • Bodnar AG, Ouellette M, Frolkis M, et al. Extension of life-span by introduction of telomerase into normal human cells. Science. 1998;279:349-352.
    • (1998) Science , vol.279 , pp. 349-352
    • Bodnar, A.G.1    Ouellette, M.2    Frolkis, M.3
  • 22
    • 33748917567 scopus 로고    scopus 로고
    • Telomeres, telomerase, and human disease
    • Artandi SE. Telomeres, telomerase, and human disease. N Engl J Med. 2006;355:1195-1197.
    • (2006) N Engl J Med , vol.355 , pp. 1195-1197
    • Artandi, S.E.1
  • 23
    • 5444238109 scopus 로고    scopus 로고
    • Genetic and epigenetic modulation of telomerase activity in development and disease
    • Liu L, Lai S, Andrews LG, Tollefsbol TO. Genetic and epigenetic modulation of telomerase activity in development and disease. Gene. 2004;340:1-10.
    • (2004) Gene , vol.340 , pp. 1-10
    • Liu, L.1    Lai, S.2    Andrews, L.G.3    Tollefsbol, T.O.4
  • 24
    • 0030819894 scopus 로고    scopus 로고
    • Telomerase catalytic subunit homologs from fission yeast and human
    • Nakamura TM, Morin GB, Chapman KB, et al. Telomerase catalytic subunit homologs from fission yeast and human. Science. 1997;277:955-959.
    • (1997) Science , vol.277 , pp. 955-959
    • Nakamura, T.M.1    Morin, G.B.2    Chapman, K.B.3
  • 25
    • 0033836212 scopus 로고    scopus 로고
    • Expression of human telomerase subunit genes in primary lung cancer and its clinical significance
    • discussion 405-406
    • Arinaga M, Shimizu S, Gotoh K, et al. Expression of human telomerase subunit genes in primary lung cancer and its clinical significance. Ann Thorac Surg. 2000;70:401-405; discussion 405-406.
    • (2000) Ann Thorac Surg , vol.70 , pp. 401-405
    • Arinaga, M.1    Shimizu, S.2    Gotoh, K.3
  • 26
    • 0035880754 scopus 로고    scopus 로고
    • Increased telomerase activity and elevated hTERT mRNA expression during multistage carcinogenesis of squamous cell carcinoma of the lung
    • Shibuya K, Fujisawa T, Hoshino H, et al. Increased telomerase activity and elevated hTERT mRNA expression during multistage carcinogenesis of squamous cell carcinoma of the lung. Cancer. 2001;92:849-855.
    • (2001) Cancer , vol.92 , pp. 849-855
    • Shibuya, K.1    Fujisawa, T.2    Hoshino, H.3
  • 27
    • 0033824264 scopus 로고    scopus 로고
    • Loss of heterozygosity assay for molecular detection of cancer using energy-transfer primers and capillary array electrophoresis
    • Medintz IL, Lee CC, Wong WW, Pirkola K, Sidransky D, Mathies RA. Loss of heterozygosity assay for molecular detection of cancer using energy-transfer primers and capillary array electrophoresis. Genome Res. 2000;10:1211-1218.
    • (2000) Genome Res , vol.10 , pp. 1211-1218
    • Medintz, I.L.1    Lee, C.C.2    Wong, W.W.3    Pirkola, K.4    Sidransky, D.5    Mathies, R.A.6
  • 28
    • 0032809589 scopus 로고    scopus 로고
    • Loss of heterozygosity in epithelial cells obtained by bronchial brushing: Clinical utility in lung cancer
    • Powell CA, Klares S, O'Connor G, Brody JS. Loss of heterozygosity in epithelial cells obtained by bronchial brushing: clinical utility in lung cancer. Clin Cancer Res. 1999;5:2025-2034.
    • (1999) Clin Cancer Res , vol.5 , pp. 2025-2034
    • Powell, C.A.1    Klares, S.2    O'Connor, G.3    Brody, J.S.4
  • 29
    • 0030876197 scopus 로고    scopus 로고
    • Microsatellite-based cancer detection using capillary array electrophoresis and energy-transfer fluorescent primers
    • Wang Y, Hung SC, Linn JF, et al. Microsatellite-based cancer detection using capillary array electrophoresis and energy-transfer fluorescent primers. Electrophoresis. 1997;18:1742-1749.
    • (1997) Electrophoresis , vol.18 , pp. 1742-1749
    • Wang, Y.1    Hung, S.C.2    Linn, J.F.3
  • 30
    • 0035136377 scopus 로고    scopus 로고
    • Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: Utility in the diagnosis of mantle cell lymphoma
    • Bijwaard KE, Aguilera NS, Monczak Y, Trudel M, Taubenberger JK, Lichy JH. Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: utility in the diagnosis of mantle cell lymphoma. Clin Chem. 2001;47:195-201.
    • (2001) Clin Chem , vol.47 , pp. 195-201
    • Bijwaard, K.E.1    Aguilera, N.S.2    Monczak, Y.3    Trudel, M.4    Taubenberger, J.K.5    Lichy, J.H.6
  • 31
    • 0035127217 scopus 로고    scopus 로고
    • Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas
    • Kumaki F, Kawai T, Hiroi S, et al. Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas. Hum Pathol. 2001;32:188-195.
    • (2001) Hum Pathol , vol.32 , pp. 188-195
    • Kumaki, F.1    Kawai, T.2    Hiroi, S.3
  • 32
    • 0032485416 scopus 로고    scopus 로고
    • Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
    • Counter CM, Meyerson M, Eaton EN, et al. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene. 1998;16:1217-1222.
    • (1998) Oncogene , vol.16 , pp. 1217-1222
    • Counter, C.M.1    Meyerson, M.2    Eaton, E.N.3
  • 33
    • 10744226749 scopus 로고    scopus 로고
    • Elevated hTERT mRNA levels: A potential determinant of bronchial squamous cell carcinoma (in situ)
    • Snijders PJ, Breuer RH, Sutedja TG, et al. Elevated hTERT mRNA levels: A potential determinant of bronchial squamous cell carcinoma (in situ). Int J Cancer. 2004:109:412-417.
    • (2004) Int J Cancer , vol.109 , pp. 412-417
    • Snijders, P.J.1    Breuer, R.H.2    Sutedja, T.G.3
  • 34
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science. 1994;266:2011-2015.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 35
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay JW, Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer. 1997;33:787-791.
    • (1997) Eur J Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 36
    • 0031456031 scopus 로고    scopus 로고
    • Telomerase activity: A biomarker of cell proliferation, not malignant transformation
    • Belair CD, Yeager TR, Lopez PM, Reznikoff CA. Telomerase activity: a biomarker of cell proliferation, not malignant transformation. Proc Natl Acad Sci U S A. 1997;94:13677-13682.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13677-13682
    • Belair, C.D.1    Yeager, T.R.2    Lopez, P.M.3    Reznikoff, C.A.4
  • 37
    • 33845629405 scopus 로고    scopus 로고
    • Smoking is associated with increased telomerase activity in short-term cultures of human bronchial epithelial cells
    • Yim HW, Slebos RJ, Randell SH, et al. Smoking is associated with increased telomerase activity in short-term cultures of human bronchial epithelial cells. Cancer Lett. 2007;246:24-33.
    • (2007) Cancer Lett , vol.246 , pp. 24-33
    • Yim, H.W.1    Slebos, R.J.2    Randell, S.H.3
  • 38
    • 7944227908 scopus 로고    scopus 로고
    • Detection of microsatellite alterations in bronchial washings in squamous cell lung cancer: The first study from India
    • Malhotra P, Behera D, Srinivasan R, et al. Detection of microsatellite alterations in bronchial washings in squamous cell lung cancer: the first study from India. Jpn J Clin Oncol. 2004;34:439-444.
    • (2004) Jpn J Clin Oncol , vol.34 , pp. 439-444
    • Malhotra, P.1    Behera, D.2    Srinivasan, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.