Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer

Cancer Research

Volumn 61, Issue 2, 2001, Pages 612-615

  Hirao, Tomoko ^a   Nelson, Heather H ^a   Ashok, Tara Devi S ^a   Wain, John C ^b   Mark, Eugene J ^b   Christiani, David C ^a,b   Wiencke, John K ^c   Kelsey, Karl T ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; PROTEIN P53; TOBACCO SMOKE;

ADULT; AGE; AGED; ARTICLE; CHROMOSOME 3; CHROMOSOME LOSS; CLINICAL FEATURE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE LOCUS; GENE MUTATION; GENOTOXICITY; HETEROZYGOSITY; HUMAN; LUNG CANCER; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; AGE FACTORS; AGED; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CHROMOSOMES, HUMAN, PAIR 3; DNA DAMAGE; DNA REPAIR; FEMALE; GENES, RAS; HUMANS; LOSS OF HETEROZYGOSITY; LUNG NEOPLASMS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; NEOPLASM STAGING; SMOKING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035863510     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

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