-
1
-
-
29144473036
-
Impaired DNA replication within progenitor cell pools promotes leukemogenesis
-
Bilousova G, Marusyk A, Porter CC, Cardiff RD, DeGregori J (2005) Impaired DNA replication within progenitor cell pools promotes leukemogenesis. PLoS Biol. 3, e401.
-
(2005)
PLoS Biol.
, vol.3
-
-
Bilousova, G.1
Marusyk, A.2
Porter, C.C.3
Cardiff, R.D.4
DeGregori, J.5
-
2
-
-
0037112844
-
'Super p53' mice exhibit enhanced DNA damage response, are tumor resistant and age normally
-
Garcia-Cao I, Garcia-Cao M, Martin-Caballero J, Criado LM, Klatt P, Flores JM, Weill JC, Blasco MA, Serrano M (2002) 'Super p53' mice exhibit enhanced DNA damage response, are tumor resistant and age normally. EMBO J. 21, 6225-6235.
-
(2002)
EMBO J.
, vol.21
, pp. 6225-6235
-
-
Garcia-Cao, I.1
Garcia-Cao, M.2
Martin-Caballero, J.3
Criado, L.M.4
Klatt, P.5
Flores, J.M.6
Weill, J.C.7
Blasco, M.A.8
Serrano, M.9
-
3
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
33749172559
-
Stem cell aging modified by the cyclin-dependent kinase inhibitor, p16 INK4a
-
Janzen V, Forkert R, Fleming H, Saito Y, Waring MT, Dombkowski DM, Cheng T, DePinho RA, Sharpless NE, Scadden DT (2006) Stem cell aging modified by the cyclin-dependent kinase inhibitor, p16 INK4a. Nature 443, 421-426.
-
(2006)
Nature
, vol.443
, pp. 421-426
-
-
Janzen, V.1
Forkert, R.2
Fleming, H.3
Saito, Y.4
Waring, M.T.5
Dombkowski, D.M.6
Cheng, T.7
DePinho, R.A.8
Sharpless, N.E.9
Scadden, D.T.10
-
5
-
-
33749187810
-
p16 INK4a induces an age-dependent decline in islet regenerative potential
-
Krishnamurthy J, Ramsey MR, Ligon KL, Torrice C, Koh A, Bonner-Weir S, Sharpless NE (2006) p16 INK4a induces an age-dependent decline in islet regenerative potential. Nature 443, 453-457.
-
(2006)
Nature
, vol.443
, pp. 453-457
-
-
Krishnamurthy, J.1
Ramsey, M.R.2
Ligon, K.L.3
Torrice, C.4
Koh, A.5
Bonner-Weir, S.6
Sharpless, N.E.7
-
6
-
-
1042266548
-
Modulation of mammalian life span by the short isoform of p53
-
Maier B, Gluba W, Bernier B, Turner T, Mohammad K, Guise T, Sutherland A, Thorner M, Scrable H (2004) Modulation of mammalian life span by the short isoform of p53. Genes Dev. 18, 306-319.
-
(2004)
Genes Dev.
, vol.18
, pp. 306-319
-
-
Maier, B.1
Gluba, W.2
Bernier, B.3
Turner, T.4
Mohammad, K.5
Guise, T.6
Sutherland, A.7
Thorner, M.8
Scrable, H.9
-
7
-
-
8644284936
-
Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging
-
Matheu A, Pantoja C, Efeyan A, Criado LM, Martin-Caballero J, Flores JM, Klatt P, Serrano M (2004) Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging. Genes Dev. 18, 2736-2746.
-
(2004)
Genes Dev.
, vol.18
, pp. 2736-2746
-
-
Matheu, A.1
Pantoja, C.2
Efeyan, A.3
Criado, L.M.4
Martin-Caballero, J.5
Flores, J.M.6
Klatt, P.7
Serrano, M.8
-
8
-
-
29944447632
-
Tumor suppression and normal aging in mice with constitutively high p53 activity
-
Mendrysa SM, O'leary KA, McElwee MK, Michalowski J, Eisenman RN, Powell DA, Perry ME (2006) Tumor suppression and normal aging in mice with constitutively high p53 activity. Genes Dev 20, 16-21.
-
(2006)
Genes Dev
, vol.20
, pp. 16-21
-
-
Mendrysa, S.M.1
O'leary, K.A.2
McElwee, M.K.3
Michalowski, J.4
Eisenman, R.N.5
Powell, D.A.6
Perry, M.E.7
-
9
-
-
33749171885
-
Declines in forebrain progenitor function and neurogenesis during aging are partially caused by increasing Ink4a expression
-
Molofsky AV, Slutsky SG, Joseph NM, He S, Pardal R, Krishnamurthy J, Sharpless NE, Morrison SJ (2006) Declines in forebrain progenitor function and neurogenesis during aging are partially caused by increasing Ink4a expression. Nature 443, 448-452.
-
(2006)
Nature
, vol.443
, pp. 448-452
-
-
Molofsky, A.V.1
Slutsky, S.G.2
Joseph, N.M.3
He, S.4
Pardal, R.5
Krishnamurthy, J.6
Sharpless, N.E.7
Morrison, S.J.8
-
11
-
-
33846646456
-
The effects of aging on tumor growth and angiogenesis are tumor-cell dependent
-
Reed MJ, Karres N, Eyman D, Cruz A, Brekken RA, Plymate S (2007) The effects of aging on tumor growth and angiogenesis are tumor-cell dependent. Int. J. Cancer 120, 753-760.
-
(2007)
Int. J. Cancer
, vol.120
, pp. 753-760
-
-
Reed, M.J.1
Karres, N.2
Eyman, D.3
Cruz, A.4
Brekken, R.A.5
Plymate, S.6
-
12
-
-
0037011958
-
p53 mutant mice that display early aging-associated phenotypes
-
Tyner SD, Venkatachalam S, Choi J, Jones S, Ghebranious N, Ingelmann H, Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty G, Bradley A, Donehower LA (2002) p53 mutant mice that display early aging-associated phenotypes. Nature 415, 45-53.
-
(2002)
Nature
, vol.415
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
Jones, S.4
Ghebranious, N.5
Ingelmann, H.6
Lu, X.7
Soron, G.8
Cooper, B.9
Brayton, C.10
Park, S.H.11
Thompson, T.12
Karsenty, G.13
Bradley, A.14
Donehower, L.A.15
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