-
1
-
-
0007102288
-
Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients
-
ENDL, J., H. OTTO, & G. JUNG, et al. 1997. Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients. J. Clin. Invest. 99: 2405-2415.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 2405-2415
-
-
ENDL, J.1
OTTO, H.2
JUNG, G.3
-
2
-
-
0028333066
-
Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus
-
LOHMANN, T., R. D. LESLIE, & M. HAWA, et al. 1994. Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus. Lancet 343: 1607-1608.
-
(1994)
Lancet
, vol.343
, pp. 1607-1608
-
-
LOHMANN, T.1
LESLIE, R.D.2
HAWA, M.3
-
3
-
-
0033012849
-
T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes
-
RHARBAOUI, F., A. MAYER, & C. GRANIER, et al. 1999. T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes. Clin. Exp. Immunol. 117: 30-37.
-
(1999)
Clin. Exp. Immunol
, vol.117
, pp. 30-37
-
-
RHARBAOUI, F.1
MAYER, A.2
GRANIER, C.3
-
4
-
-
0027958831
-
Epitopes of GAD 65 in insulin-dependent diabetes mellitus
-
ARMSTRONG, N.W. & D.B. JONES. 1994. Epitopes of GAD 65 in insulin-dependent diabetes mellitus. Lancet 344: 406-407.
-
(1994)
Lancet
, vol.344
, pp. 406-407
-
-
ARMSTRONG, N.W.1
JONES, D.B.2
-
5
-
-
0033553645
-
Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells
-
YOON, J.W., C.S. YOON, & H.W. LIM, et al. 1999. Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells. Science 284: 1183-1187.
-
(1999)
Science
, vol.284
, pp. 1183-1187
-
-
YOON, J.W.1
YOON, C.S.2
LIM, H.W.3
-
6
-
-
0030759825
-
Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101, beta1*0401) transgenic mice
-
PATEL, S.D., A.P. COPE, & M. CONGIA, et al. 1997. Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101, beta1*0401) transgenic mice. Proc. Natl. Acad. Sci. USA 94: 8082-8087.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8082-8087
-
-
PATEL, S.D.1
COPE, A.P.2
CONGIA, M.3
-
7
-
-
0035852674
-
Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65)
-
NEPOM, G.T., J.D. LIPPOLIS, & F.M. WHITE, et al. 2001. Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65). Proc. Natl. Acad. Sci. USA 98: 1763-1768.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1763-1768
-
-
NEPOM, G.T.1
LIPPOLIS, J.D.2
WHITE, F.M.3
-
8
-
-
0036312395
-
Detection of GAD65 specific T-cells by MHC class II multimers in type 1 diabetes patients and at-risk subjects
-
REIJONEN, H., E.J. NOVAK, & S. KOCHIK, et al. 2002. Detection of GAD65 specific T-cells by MHC class II multimers in type 1 diabetes patients and at-risk subjects. Diabetes 51: 1375-1382.
-
(2002)
Diabetes
, vol.51
, pp. 1375-1382
-
-
REIJONEN, H.1
NOVAK, E.J.2
KOCHIK, S.3
-
9
-
-
27844561478
-
GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects
-
OLING, V., J.MARTTILA, & J. ILONEN, et al. 2005. GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects. J. Autoimmun. 25: 235-243.
-
(2005)
J. Autoimmun
, vol.25
, pp. 235-243
-
-
OLING, V.1
MARTTILA, J.2
ILONEN, J.3
-
10
-
-
1942507364
-
Detection of CD4 +autoreactive T cells in T1D using HLA class II tetramers
-
REIJONEN, H., W.W. KWOK & G.T. NEPOM. 2003. Detection of CD4 +autoreactive T cells in T1D using HLA class II tetramers. Ann. N. Y. Acad. Sci. 1005: 82-87.
-
(2003)
Ann. N. Y. Acad. Sci
, vol.1005
, pp. 82-87
-
-
REIJONEN, H.1
KWOK, W.W.2
NEPOM, G.T.3
-
11
-
-
3242768392
-
GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes
-
REIJONEN, H., R. MALLONE, & A.K. HENINGER, et al. 2004. GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes. Diabetes 53: 1987-1994.
-
(2004)
Diabetes
, vol.53
, pp. 1987-1994
-
-
REIJONEN, H.1
MALLONE, R.2
HENINGER, A.K.3
-
12
-
-
0027908753
-
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
-
TISCH, R., X.D. YANG, & S.M. SINGER, et al. 1993. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366: 72-75.
-
(1993)
Nature
, vol.366
, pp. 72-75
-
-
TISCH, R.1
YANG, X.D.2
SINGER, S.M.3
-
13
-
-
0027368141
-
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
-
KAUFMAN, D.L., M. CLARE-SALZLER, & J. TIAN, et al. 1993. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature 366: 69-72.
-
(1993)
Nature
, vol.366
, pp. 69-72
-
-
KAUFMAN, D.L.1
CLARE-SALZLER, M.2
TIAN, J.3
-
14
-
-
0034598313
-
In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes
-
WEN, L., F.S. WONG, & J. TANG, et al. 2000. In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes. J. Exp. Med. 191: 97-104.
-
(2000)
J. Exp. Med
, vol.191
, pp. 97-104
-
-
WEN, L.1
WONG, F.S.2
TANG, J.3
-
15
-
-
33750959226
-
Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabeticprone RIP-B7/DR4 mice
-
GEBE, J.A., K.A. UNRATH, & B.A. FALK, et al. 2006. Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabeticprone RIP-B7/DR4 mice. Clin. Immunol. 121: 294-304.
-
(2006)
Clin. Immunol
, vol.121
, pp. 294-304
-
-
GEBE, J.A.1
UNRATH, K.A.2
FALK, B.A.3
-
16
-
-
0035061420
-
The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model
-
WEN, L., N.Y. CHEN, & J. TANG, et al. 2001. The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model. J. Clin. Invest 107: 871-880.
-
(2001)
J. Clin. Invest
, vol.107
, pp. 871-880
-
-
WEN, L.1
CHEN, N.Y.2
TANG, J.3
-
17
-
-
18744385526
-
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope
-
KENT, S.C., Y. CHEN, & L. BREGOLI, et al. 2005. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope. Nature 435: 224-228.
-
(2005)
Nature
, vol.435
, pp. 224-228
-
-
KENT, S.C.1
CHEN, Y.2
BREGOLI, L.3
-
18
-
-
34249053752
-
Impaired islet function in DR4-restricted GAD65 TcR transgenic DR4 mice
-
Submitted for publication
-
GEBE J.A., B.A. FALK, & K.A. UNRATH, et al. 2007. Impaired islet function in DR4-restricted GAD65 TcR transgenic DR4 mice. Submitted for publication.
-
(2007)
-
-
GEBE, J.A.1
FALK, B.A.2
UNRATH, K.A.3
-
19
-
-
0030779118
-
A mechanism for the major histocompatibility complex-linked resistance to autoimmunity
-
SCHMIDT, D., J. VERDAGUER, N. AVERILL & P. SANTAMARIA. 1997. A mechanism for the major histocompatibility complex-linked resistance to autoimmunity. J. Exp. Med. 186: 1059-1075.
-
(1997)
J. Exp. Med
, vol.186
, pp. 1059-1075
-
-
SCHMIDT, D.1
VERDAGUER, J.2
AVERILL, N.3
SANTAMARIA, P.4
-
20
-
-
0030588572
-
Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains
-
VERDAGUER, J., J.W. YOON, & B. ANDERSON, et al. 1996. Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains. J. Immunol. 157: 4726-4735.
-
(1996)
J. Immunol
, vol.157
, pp. 4726-4735
-
-
VERDAGUER, J.1
YOON, J.W.2
ANDERSON, B.3
-
21
-
-
0030724897
-
Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice
-
VERDAGUER, J., D. SCHMIDT, & A. AMRANI, et al. 1997. Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice. J. Exp. Med. 186: 1663-1676.
-
(1997)
J. Exp. Med
, vol.186
, pp. 1663-1676
-
-
VERDAGUER, J.1
SCHMIDT, D.2
AMRANI, A.3
-
22
-
-
0034657180
-
Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice
-
KANAGAWA, O., J. SHIMIZU & B.A. VAUPEL. 2000. Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice. J. Immunol. 164: 5466-5473.
-
(2000)
J. Immunol
, vol.164
, pp. 5466-5473
-
-
KANAGAWA, O.1
SHIMIZU, J.2
VAUPEL, B.A.3
-
23
-
-
0037237655
-
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood
-
TRUDEAU, J.D., C. KELLY-SMITH, & C. B. VERCHERE, et al. 2003. Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood. J. Clin. Invest. 111: 217-223.
-
(2003)
J. Clin. Invest
, vol.111
, pp. 217-223
-
-
TRUDEAU, J.D.1
KELLY-SMITH, C.2
VERCHERE, C.B.3
-
24
-
-
1342308440
-
T-cell receptor transgenic (TCR-Tg) mice from two diabetogenic CD4+ islet-antigen-specific T-cell clones
-
HASKINS, K. 2004. T-cell receptor transgenic (TCR-Tg) mice from two diabetogenic CD4+ islet-antigen-specific T-cell clones. J. Autoimmun. 22: 107-109.
-
(2004)
J. Autoimmun
, vol.22
, pp. 107-109
-
-
HASKINS, K.1
-
25
-
-
1842475452
-
T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes
-
PAUZA, M.E., C.M. DOBBS, & J. HE, et al. 2004. T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes. Diabetes 53: 978-988.
-
(2004)
Diabetes
, vol.53
, pp. 978-988
-
-
PAUZA, M.E.1
DOBBS, C.M.2
HE, J.3
-
26
-
-
0037136283
-
CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer
-
TARBELL, K.V., M. LEE, & E. RANHEIM, et al. 2002. CD4(+) T cells from glutamic acid decarboxylase (GAD)65-specific T cell receptor transgenic mice are not diabetogenic and can delay diabetes transfer. J. Exp. Med. 196: 481-492.
-
(2002)
J. Exp. Med
, vol.196
, pp. 481-492
-
-
TARBELL, K.V.1
LEE, M.2
RANHEIM, E.3
-
27
-
-
2442522323
-
Autoreactive T cells in healthy individuals
-
DANKE, N.A., D.M. KOELLE, & C. YEE, et al. 2004. Autoreactive T cells in healthy individuals. J. Immunol. 172: 5967-5972.
-
(2004)
J. Immunol
, vol.172
, pp. 5967-5972
-
-
DANKE, N.A.1
KOELLE, D.M.2
YEE, C.3
-
28
-
-
0025340804
-
Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-yr follow-up of the Seattle Family Study
-
MCCULLOCH, D.K., L.J. KLAFF, & S.E. KAHN, et al. 1990. Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-yr follow-up of the Seattle Family Study. Diabetes 39: 549-556.
-
(1990)
Diabetes
, vol.39
, pp. 549-556
-
-
MCCULLOCH, D.K.1
KLAFF, L.J.2
KAHN, S.E.3
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