Can life before birth affect health ever after?

Current Women's Health Reviews

Volumn 3, Issue 2, 2007, Pages 79-88

  Dickinson, Hayley ^a   Wintour, E Marelyn ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Fetal programming; Glucocorticoids; Low protein; Maternal stress

Indexed keywords

CAPSAICIN; DEXAMETHASONE; ENALAPRIL; GLUCOCORTICOID; RETINOIC ACID; SOMATOMEDIN C;

ADULT DISEASE; ARTERY LIGATION; ATTENTION DEFICIT DISORDER; AUTISM; BREATHING RATE; CARDIOVASCULAR RISK; DEVELOPMENTAL DISORDER; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; DISEASE SEVERITY; ENVIRONMENTAL FACTOR; FETOTOXICITY; FETUS DEVELOPMENT; FETUS MORTALITY; GENETIC RISK; GESTATIONAL AGE; GROWTH RETARDATION; HEALTH STATUS; HIGH RISK POPULATION; HUMAN; HYPERTENSION; INTRAUTERINE GROWTH RETARDATION; ISCHEMIC HEART DISEASE; LOW BIRTH WEIGHT; MALNUTRITION; MATERNAL NUTRITION; MATERNAL STRESS; METABOLIC SYNDROME X; NONHUMAN; ONSET AGE; PATHOPHYSIOLOGY; PHENOTYPE; POSTTRAUMATIC STRESS DISORDER; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROTEINURIA; REVIEW; RISK ASSESSMENT; RISK FACTOR; SCHIZOPHRENIA; STILLBIRTH; SYSTEMIC DISEASE; SYSTOLIC BLOOD PRESSURE; TACHYCARDIA; UTERINE ARTERY;

EID: 34248631415     PISSN: 15734048     EISSN: None     Source Type: Journal    
DOI: 10.2174/1573404810703020079     Document Type: Review

References (81)

1. Barker DJ, Osmond C. Infant mortality, childhood nutrition, and ischaemic heart disease in England and Wales. Lancet 1986; 1(8489): 1077-81.
2. Law C, Shiell A. Is blood pressure inversely related to birth weight? The strength of evidence from a systematic review of the literature. J Hypertens 1996; 14: 935-41.
3. Roseboom T, van der Meulen J, Ravelli A, Osmond C, Barker D, Bleker O. Effects of prenatal exposure to the dutch famine on adult disease in later life: An overview. Twin Res 2001; 4(5): 293-8.
4. Steer PJ, Little MP, Kold-Jensen T, Chapple J, Elliott P. Maternal blood pressure in pregnancy, birth weight, and perinatal mortality in first births: prospective study. BMJ 2004; 4: 329(7478): 1312.
5. Wood S, Jick H, Sauvet R. The risk of stillbirth in pregnancies before and after the onset of diabetes. Diabetic Med 2003; 20: 703-7.
6. Sobngwi E, Boudou P, Mauvais-Jarvis F, et al. Effect of diabetic environment in utero on predisposition to type 2 diabetes. Lancet 2003; 361(9372): 1861-5.
7. Perkin MR, Bland JM, Peacock JL, Anderson HR. The effect of anxiety and depression during pregnancy on obstetric complications. Br J Obstet Gynaecoll 993; 100(7): 629-34.
8. Hedegaard M, Henriksen TB, Secher NJ, Hatch MC, Sabroe S. Do stressful life events affect duration of gestation and risk of preterm delivery? Epidemiology 1996; 7(4): 339-45.
9. Copper RL, Goldenberg RL, Das A, et al. The preterm prediction study: maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks' gestation. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Am J Obstet Gynecol 1996; 175(5): 1286-92.
10. Wadhwa PD, Sandman CA, Porto M, Dunkel-Schetter C, Garite TJ. The association between prenatal stress and infant birth weight and gestational age at birth: a prospective investigation. Am J Obstet Gynecol 1993; 169(4): 858-65.
11. Glynn LM, Wadhwa PD, Dunkel-Schetter C, Chicz-Demet A, Sandman CA. When stress happens matters: effects of earthquake timing on stress responsivity in pregnancy. Am J Obstet Gynecol 2001; 184(4): 637-42.
12. Yehuda R, Engel SM, Brand SR, Seckl J, Marcus SM, Berkowitz GS. Transgenerational effects of posttraumatic stress disorder in babies of mothers exposed to the World Trade Center attacks during pregnancy. J Clin Endocrinol Metab 2005; 90(7): 4115-8.
13. Harding JE. The nutritional basis of the fetal origins of adult disease. Int J Epidemiol 2001; 30(1): 15-23.
14. West-Eberhard M. Phenotypic plasticity and the origins of diversity. Annu Rev Ecol Syst 1989; 20: 249-78.
15. Metcalfe NB, Monaghan P. Compensation for a bad start: grow now, pay-later? Trends Ecol Evol 2001; 1: 16(5): 254-60.
16. Lucas A. Programming by early nutrition in man. Ciba Found Symp 1991; 156: 38-50.
17. Woodall SM, Johnston BM, Breier BH, Gluckman PD. Chronic maternal undernutrition in the rat leads to delayed postnatal growth and elevated blood pressure of offspring. Pediatr Res 1996; 40(3): 438-43.
18. Lucas SR, Costa Silva VL, Miraglia SM, Zaladek Gil F. Functional and morphometric evaluation of offspring kidney after intrauterine undernutrition. Pediatr Nephrol1997; 11(6): 719-23.
19. Holemans K, Gerber R, Meurrens K, De Clerck F, Poston L, Van Assche FA. Maternal food restriction in the second half of pregnancy affects vascular function but not blood pressure of rat female offspring. Br J Nutr 1999; 81(1): 73-9.
20. Hawkins P, Steyn C, Ozaki T, Saito T, Noakes D, Hanson M. Effect of maternal undernutrition in early gestation on ovine fetal blood pressure and cardiovascular reflexes. Am J Physiol Regul Intergr Comp Physiol 2000; 279: R340-R8.
21. Ozaki T, Nishina H, Hanson MA, Poston L. Dietary restriction in pregnant rats causes gender-related hypertension and vascular dysfunction in offspring. J Physiol 2001; 530: 141-52.
22. Lesage J, Blondeau B, Grino M, Breant B, Dupouy JP. Maternal undernutrition during late gestation induces fetal overexposure to glucocorticoids and intrauterine growth retardation, and disturbs the hypothalamo-pituitary adrenal axis in the newborn rat. Endocrinology 2001; 142(5): 1692-702.
23. Vickers M, Ikenasio B, Breier B. IGF-I treatment reduces hyperphagia, obesity, and hypertension in metabolic disorders induced by fetal programming. Endocrinology 2001; 142(9): 3964-73.
24. Kind KL, Simonetta G, Clifton PM, Robinson JS, Owens JA. Effect of maternal feed restriction on blood pressure in the adult guinea pig. Exp Physiol 2002; 87.4: 2359-67.
25. Perez H, Ruiz S, Soto-Moyano R. Prenatal malnutrition-induced hypertension in young rats is prevented by neonatal capsaicin treatment. Neurosci Lett 2002; 16; 328(3): 253-6.
26. Edwards LJ, Bryce AE, Coulter CL, McMillen IC. Maternal undernutrition throughout pregnancy increases adrenocorticotrophin receptor and steroidogenic acute regulatory protein gene expression in the adrenal gland of twin fetal sheep during late gestation. Mol Cell Endocrinol 2002; 31; 196(1-2): 1-10.
27. Bloomfield FH, Oliver MH, Giannoulias CD, Gluckman PD, Harding JE, Challis JR. Brief undernutrition in late-gestation sheep programs the hypothalamic-pituitary-adrenal axis in adult offspring. Endocrinol 2003; 144(7): 2933-40.
28. Langley-Evans S, Browne R, Jackson A. Altered glucose tolerance in rats exposed to maternal low protein diets in utero. Comp Biochem Physiol 1994; 109(2): 223-9.
29. Langley-Evans S, Welham S, Sherman R, Jackson A. Weanling rats exposed to maternal low-protein diets during discrete periods of gestation exhibit differing severity of hypertension. Clin Sci 1996; 91: 607-15.
30. Kwong W, Wild A, Roberts P, Willis A, Fleming T. Maternal undernutrition during preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension. Development 2000; 127: 4195-202.
31. Manning J, Vehaskari V. Low birth weight-associated adult hypertension in the rat. Pediat Nephrol 2001; 16: 417-22.
32. Vehaskari VM, Aviles DH, Manning J. Prenatal programming of adult hypertension in the rat. Kidney Int 2001; 59(1): 238-45.
33. Woods L, Ingelfinger J, Nyengaard J, Rasch R. Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats. Pediat Res 2001; 49(4): 460-7.
34. Jackson A, Dunn R, Marchand M, Langley-Evans S. Increased systolic blood pressure in rats induced by a maternal low-protein diet is reversed by dietary supplementation with glycine. Clin Sci 2002; 103: 633-9.
35. Lelievre-Pegorier M, Vilar J, Ferrier M, et al. Mild vitamin A deficiency leads to inborn nephron deficit in the rat. Kidney Int 1998; 54: 1455-62.
36. Gambling L, Dunford S, Wallace DI, Zuur G, Solanky N, Srai SK, et al. Iron deficiency during pregnancy affects postnatal blood pressure in the rat. J Physiol 2003; 15; 552(Pt 2): 603-10.
37. Bergel E, Belizan J. A deficient maternal calcium intake during pregancy increases blood pressure of the offspring in adult rats. Br J Obstet Gynaecol 2002; 109: 540-5.
38. Fanaroff A, Martin R. Neonatal-perinatal medicine disease of the fetus and infant. 6 ed: Mosby Year Book; 1997.
39. Persson E, Jansson T. Low birth weight is associated with elevated adult blood pressure in the chronically catheterized guinea-pig. Acta Physiol Scand 1992; 145(2): 195-6.
40. Merlet-Beníchou C, Gilbert T, Muffat-Joly M, Lelievre-Pegorier M, Leroy B. Intrauterine growth retardation leads to a permanent nephron deficit in the rat. Pediatr Nephrol 1994; 8(2): 175-80.
41. Sanders MW, Fazzi GE, Janssen GM, de Leeuw PW, Blanco CE, De Mey JG. Reduced uteroplacental blood flow alters renal arterial reactivity and glomerular properties in the rat offspring. Hypertension 2004; 43 (6): 1283-9.
42. Pham TD, MacLennan NK, Chiu CT, Laksana GS, Hsu JL, Lane RH. Uteroplacental insufficiency increases apoptosis and alters p53 gene methylation in the full-term IUGR rat kidney. Am J Physiol Regul Integr Comp Physiol 2003; 285(5): 962-70.
43. Barbazanges A, Piazza P, Le Moal M, Maccari S. Maternal glucocorticoid secretion mediates long-term effects of prenatal stress. The Journal of Neuroscience 1996; 16(12): 3943-9.
44. Morley-Fletcher S, Rea M, Maccari S, Laviola G. Environmental enrichment during adolescence reverses the effects of prenatal stress on play behaviour and HPA axis reactivity in rats. Eur J Neurosci 2003; 18(12): 3367-74.
45. Coe CL, Kramer M, Kirschbaum C, Netter P, Fuchs E. Prenatal stress diminishes the cytokine response of leukocytes to endotoxin stimulation in juvenile rhesus monkeys. J Clin Endocrinol Metab 2002; 87(2): 675-81.
46. Marchlewska-Koj A, Kapusta J, Kruczek M. Prenatal stress modifies behavior in offspring of bank voles (Clethrionomys glareolus). Physiol Behav 2003; 79(4-5): 671-8.
47. Marchiewska-Koj A, Kruczek M, Kapusta J, Pochron E. Prenatal stress affects the rate of sexual maturation and attractiveness in bank voles. Physiol Behav 2003; 79(2): 305-10.
48. Igosheva N, Klimova O, Anishchenko T, Glover V. Prenatal stress alters cardiovascular responses in adult rats. J Physiol 2004; 15; 557(Pt 1): 273-85.
49. Woods LL, Weeks DA. Prenatal programming of adult blood pressure: role of maternal corticosteroids. Am J Physiol Regul Integr Comp Physiol 2005; 289(4): 955-62.
50. Dodic M, May CN, Wintour EM, Coghlan JP. An early prenatal exposure to excess glucocorticoid leads to hypertensive offspring in sheep. Clin Sci (Lond) 1998; 94(2): 149-55.
51. Wintour EM, Moritz KM, Johnson K, Ricardo S, Samuel CS, Dodic M. Reduced nephron number in adult sheep, hypertensive as a result of prenatal glucocorticoid treatment. J Physiol 2003; 549: 929-35.
52. Dodic M, Hantzis V, Duncan J, et al. Programming effects of short prenatal exposure to cortisol. FASEB J 2002; 16: 1017-26.
53. Ortiz LA, Quan A, Weinberg A, Baum M. Effect of prenatal dexamethasone on rat renal development. Kidney Int 2001; 59(5): 1663-9.
54. Ortiz LA, Quan A, Zarzar F, Weinberg A, Baum M. Prenatal dexamethasone programs hypertension and renal injury in the rat. Hypertension 2003; 41(2): 328-34.
55. Dodic M, Moritz K, Koukoulas I, Wintour EM. Programmed hypertension: kidney, brain or both? Trends Endocrinol Metab 2002; 13(9): 403-8.
56. Dickinson H, Moritz K, Wintour EM, Walker DW. Maternal dexamethasone treatment at mid-gestation reduces nephron number and alters renal gene expression in the fetal spiny mouse. Am J Physiol 2007; 292(1): R453-61.
57. Drake AJ, Walker BR, Seckl JR. Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats. Am J Physiol Regul Integr Comp Physiol 2005; 288(1): R34-8.
58. Benediktsson R, Lindsay R, Noble J, Seckl J, Edwards C. Glucocorticoid exposure in utero: new model for adult hypertension. Lancet 1993; 341: 339-41.
59. Hadoke PW, Lindsay RS, Seckl JR, Walker BR, Kenyon CJ. Altered vascular contractility in adult female rats with hypertension programmed by prenatal glucocorticoid exposure. J Endocrinol 2006; 188(3): 435-42.
60. Holmes MC, Abrahamsen CT, French KL, Paterson JM, Mullins JJ, Seckl JR. The mother or the fetus? 11beta-hydroxysteroid dehydrogenase type 2 null mice provide evidence for direct fetal programming of behavior by endogenous glucocorticoids. J Neurosci 2006; 26(14): 3840-4.
61. Louey S, Thornburg KL. The prenatal environment and later cardiovascular disease. Early Hum Dev. 2005; 81(9): 745-51.
62. Li G, Xiao Y, Estrella JL, Ducsay CA, Gilbert RD, Zhang L. Effect of fetal hypoxia on heart susceptibility to ischemia and reperfusion injury in the adult rat. J Soc Gynecol Investig 2003; 10(5): 265-74.
63. Godfrey KM. The role of the placenta in fetal programming-a review. Placenta 2002; 23: S20-7.
64. Myatt L, Roberts V. Placental mechanisms and developmental origins of health and disease. In: Gluckman P, Hanson M, editors. Developmental origins of health and disease. Cambridge: Cambridge University Press; 2006; 130-42.
65. Coan PM, Burton GJ, Ferguson-Smith AC. Imprinted genes in the placenta - a review. Placenta 2005; 26 (Suppl A): S10-20.
66. Reik W, Constancia M, Fowden A, Anderson N, Dean W, Ferguson-Smith A, et al. Regulation of supply and demand for maternal nutrients in mammals by imprinted genes. J Physiol 2003; 547(Pt 1): 35-44.
67. Vickaryous N, Whitelaw E. Modifications of epigenetics state through dietary manipulation in the developing mammalian embryo. In: Wintour EM, Owens JA, Eds, Early life origins of health and disease. Texas: Springer Science; 2006; 70-8.
68. Rees WD, Hay SM, Antipatis C. The effect of dietary protein on the amino acid supply and threonine metabolism in the pregnant rat. Reprod Nutr Dev 2006; 46(3): 227-39.
69. Thomassin H, Flavin M, Espinas ML, Grange T. Glucocorticoid-induced DNA demethylation and gene memory during development. EMBO J 2001; 20(8): 1974-83.
70. McConnell J. A mitochondrial component of developmental programming. In: Gluckman P, Hanson M, Eds, Developmental origins of health and disease. Cambridge: Cambridge University Press; 2006; 75-81.
71. Song J, Oh JY, Sung YA, Pak YK, Park KS, Lee HK. Peripheral blood mitochondrial DNA content is related to insulin sensitivity in offspring of type 2 diabetic patients. Diabetes Care 2001; 24(5): 865-9.
72. Ballinger SW, Patterson C, Knight-Lozano CA, et al. Mitochondrial integrity and function in atherogenesis. Circulation 2002; 106(5): 544-9.
73. Trifunovic A, Wredenberg A, Falkenberg M, et al. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 2004 27; 429(6990): 417-23.
74. Taylor PD, McConnell J, Khan IY, Holemans K, Lawrence KM, Asare-Anane H, et al. Impaired glucose homeostasis and mitochondrial abnormalities in offspring of rats fed a fat-rich diet in pregnancy. Am J Physiol Regul Integr Comp Physiol 2005; 288(1): R134-9.
75. Wu YH, Fischer DF, Kalsbeek A, et al. Pineal clock gene oscillation is disturbed in Alzheimer's disease, due to functional disconnection from the "master clock". FASEB J 2006; 20(11): 1874-6.
76. Kondratov RV, Kondratova AA, Gorbacheva VY, Vykhovanets OV, Antoch MP. Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock. Genes Dev 2006; 20(14): 1868-73.
77. De Leersnyder H, Claustrat B, Munnich A, Verloes A. Circadian rhythm disorder in a rare disease: Smith-Magenis syndrome. Mol Cell Endocrinol 2006; 252(1-2): 88-91.
78. Jilg A, Moek J, Weaver DR, Korf HW, Stehle JH, von Gall C. Rhythms in clock proteins in the mouse pars tuberalis depend on MT1 melatonin receptor signalling. Eur J Neurosci 2005; 22(11): 2845-54.
79. Torres-Farfan C, Rocco V, Monso C, et al. Maternal melatonin effects on clock gene expression in a non-human primate fetus. Endocrinology 2006; 147(10): 4618-26.
80. Sumova A, Bendova Z, Sladek M, Kovacikova Z, El-Hennamy R, Laurinova K, et al. The rat circadian clockwork and its photoperiodic entrainment during development. Chronobiol Int 2006; 23(1-2): 237-43.
81. Chen CP, Kuhn P, Advis JP, Sarkar DK. Prenatal ethanol exposure alters the expression of period genes governing the circadian function of beta-endorphin neurons in the hypothalamus. J Neurochem 2006; 97(4): 1026-33.