Synthesis and in vivo evaluation in mice of (123I)-(4- fluorophenyl)(1-(3-iodophenethyl)piperidin-4-yl) methanone as a potential SPECT-tracer for the serotonin 5-HT2A receptor

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 50, Issue 3, 2007, Pages 183-188

  Blanckaert, P ^a   Burvenich, I ^a   Devos, F ^a   Slegers, G ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

5 HT2A receptor; Antagonist; Radiotracer; Serotonin; SPECT

Indexed keywords

MAMMALS;

5-HT2A RECEPTOR; ANTAGONIST; IN-VIVO; METHANONE; RADIOLABELLING; RADIOTRACER; SEROTONIN; SPECT; SYNTHESISED; VIVO EVALUATION;

TISSUE;

1 BROMO 3 (2 BROMOETHYL)BENZENE; 2 (3 BROMOPHENYL)ETHANOL; 4 FLUOROPHENYL[1 (3 IODOPHENETHYL)PIPERIDIN 4 YL]METHANONE I 123; BIS(TRIBUTYLTIN) OXIDE; SEROTONIN 2A RECEPTOR; TRACER; UNCLASSIFIED DRUG; [1 (3 IODOPHENETHYL)PIPERIDIN 4 YL](4 FLUORPHENYL)METHANONE; [1 (3 TRIBUTYLSTANNYLPHENETHYL)PIPERIDIN 4 YL](4 FLUORPHENYL)METHANONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; EVALUATION; IN VIVO STUDY; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; RADIOCHEMISTRY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALIA; MUS;

EID: 34248583998     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1251     Document Type: Article

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