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Volumn 45, Issue 11, 2002, Pages 2319-2324

Synthesis, receptor potency, and selectivity of halogenated diphenylpiperidines as serotonin 5-HT2a ligands for PET or SPECT brain imaging

(7) Fu, Xing a Tan, Ping Zhong a,b Kula, Nora S c Baldessarini, Ross c Tamagnan, Gilles a Innis, Robert B a Baldwin, Ronald M a

a YALE UNIVERSITY SCHOOL OF MEDICINE (United States)

b HONEYWELL (United States)

c MASSACHUSETTS GENERAL HOSPITAL (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(4 FLUOROPHENYL)[1 [2 (4 FLUOROPHENYL)ETHYL]PIPERIDIN 4 YL]METHANOL; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; BENZOYL 4 PIPERIDINE DERIVATIVE; DOPAMINE 2 RECEPTOR; HALIDE; PHENYL 4 PIPERIDINYLMETHANOL DERIVATIVE; PIPERIDINE DERIVATIVE; SEROTONIN 2A AGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN 6 RECEPTOR; SEROTONIN 7 RECEPTOR; SODIUM BOROHYDRIDE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BRAIN TOMOGRAPHY; DRUG DETERMINATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; ISOTOPE LABELING; POSITRON EMISSION TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALS; COS CELLS; HUMANS; LIGANDS; PIPERIDINES; PROSENCEPHALON; RADIOLIGAND ASSAY; RATS; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, DOPAMINE D2; RECEPTORS, SEROTONIN; STRUCTURE-ACTIVITY RELATIONSHIP; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0037161578 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm0200411 Document Type: Article

Times cited : (10)

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