Characterization of the SPECT 5-HT2A receptor ligand 123I-R91150 in healthy volunteers: Part 1 - Pseudoequilibrium interval and quantification methods

Journal of Nuclear Medicine

Volumn 47, Issue 6, 2006, Pages 919-928

  Catafau, Ana M ^a,b,i   Danus, Monica ^b   Bullich, Santiago ^b   Llop, Jordi ^c   Perich, Javier ^b   Cunningham, Vincent J ^d   Plaza, Pedro ^b   Penengo, Maria M ^b   Eersels, Jos L H ^e   Squassante, Lisa ^f   Ros, Domenec ^g   Barbanoj, Manel ^h  

^a Psychiatry Centre of Excellence for Drug Discovery   (Spain)

^b HOSPITAL DEL MAR   (Spain)

^c Institut d'Alta Tecnologia   (Spain)

^d GLAXOSMITHKLINE   (United Kingdom)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^f GSK   (Italy)

^g UNIVERSITY OF BARCELONA   (Spain)

^h HOSPITAL SANT PAU   (Spain)

ⁱ GLAXOSMITHKLINE   (Spain)

Author keywords

5 HT 2A; 123I R91150; Molecular imaging; Neurotransmission; SPECT

Indexed keywords

4 AMINO N [1 [3 (4 FLUOROPHENOXY)PROPYL] 4 METHYL 4 PIPERIDINYL] 5 IODO 2 METHOXYBENZAMIDE I 123; R 91150; RADIOLIGAND; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; LIGAND; PIPERIDINE DERIVATIVE; RADIOACTIVE IODINE; RADIOPHARMACEUTICAL AGENT;

ADULT; ARTICLE; BLOOD SAMPLING; BRAIN REGION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG UPTAKE; HUMAN; HUMAN EXPERIMENT; MALE; MOLECULAR IMAGING; NORMAL HUMAN; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; BRAIN; CLINICAL TRIAL; COMPUTER ASSISTED DIAGNOSIS; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; REFERENCE VALUE; SCINTISCANNING; TISSUE DISTRIBUTION;

ADULT; BRAIN; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IODINE RADIOISOTOPES; LIGANDS; MALE; METABOLIC CLEARANCE RATE; PIPERIDINES; RADIOPHARMACEUTICALS; RECEPTOR, SEROTONIN, 5-HT2A; REFERENCE VALUES; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 33746091391     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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