Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 321, Issue 3, 2007, Pages 911-920

  Guo, Jun ^a   Massaeli, Hamid ^a   Li, Wentao ^a   Xu, Jianmin ^a   Luo, Tao ^a   Shaw, James ^a   Kirshenbaum, Lorrie A ^a   Zhang, Shetuan ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CESIUM ION; POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; PROBUCOL; 1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ANTIARRHYTHMIC AGENT; CESIUM; KCNH2 PROTEIN, HUMAN; KCNH2 PROTEIN, RAT; PIPERIDINE DERIVATIVE; POTASSIUM; PYRIDINE DERIVATIVE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; FEMALE; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HUMAN; HUMAN CELL; KIDNEY CELL; LONG QT SYNDROME; MALE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; ACTION POTENTIAL; ANIMAL; CELL CULTURE; CELL LINE; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; ELECTROPHYSIOLOGY; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATCH CLAMP; PHYSIOLOGY; PROTEIN TRANSPORT; SPRAGUE DAWLEY RAT;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ANTI-ARRHYTHMIA AGENTS; CELL LINE; CELL MEMBRANE; CELLS, CULTURED; CESIUM; ELECTROPHYSIOLOGY; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; GENE EXPRESSION; HUMANS; MALE; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PIPERIDINES; POTASSIUM; PROBUCOL; PROTEIN TRANSPORT; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 34248583575     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.120931     Document Type: Article

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