The diagnosis of children with central diabetes insipidus

Journal of Pediatric Endocrinology and Metabolism

Volumn 20, Issue 3, 2007, Pages 359-375

  Ghirardello, Stefano ^a   Garrè, Maria Luisa ^b   Rossi, Andrea ^b   Maghnie, Mohamad ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Anterior pituitary; AVP II gene; Central diabetes insipidus; Germinoma; Langerhans cell histiocytosis; MRI; Posterior pituitary; Vasopressin; Wolfram syndrome

Indexed keywords

AQUAPORIN 2; ARGIPRESSIN; DESMOPRESSIN; VASOPRESSIN;

ADIPSIA; AUTOIMMUNE DISEASE; AUTOSOMAL DOMINANT INHERITANCE; AUTOSOMAL RECESSIVE INHERITANCE; BRAIN MALFORMATION; BRAIN METASTASIS; CHROMOSOME 20P; CLINICAL EXAMINATION; CLINICAL FEATURE; CLINICAL OBSERVATION; CRANIOPHARYNGIOMA; DIABETES INSIPIDUS; DIAGNOSTIC ACCURACY; DIFFERENTIAL DIAGNOSIS; FLUID THERAPY; GERM CELL TUMOR; HISTIOCYTOSIS X; HUMAN; HYPEROSMOLALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; REVIEW; SARCOIDOSIS; SUPRAOPTIC NUCLEUS; THALAMUS MIDLINE NUCLEUS; THIRST; WOLFRAM SYNDROME; X CHROMOSOME LINKED DISORDER; BRAIN TUMOR; CHILD; GENETICS; NEUROGENIC DIABETES INSIPIDUS; PATHOLOGY;

BRAIN NEOPLASMS; CHILD; CRANIOPHARYNGIOMA; DIABETES INSIPIDUS, NEUROGENIC; GERMINOMA; HUMANS; MAGNETIC RESONANCE IMAGING;

EID: 34248571683     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2007.20.3.359     Document Type: Review

References (97)

1. Maghnie M, Cosi G, Genovese E, Manca-Bitti ML, Cohen A, Zecca S, Tinelli C, Gallucci M, Bernasconi S, Boscherini B, Severi F, Arico M. Central diabetes insipidus in children and young adults. N Engl J Med 2000; 343: 998-1007.
2. Mootha SL, Barkovich AJ, drumbach MM, Edwards MS, Gitelman SE, Kaplan SL, Conte FA. Idiopathic hypothalamic diabetes insipidus, pituitary stalk thickening, and the occult intracranial germinoma in children and adolescents. J Clin Endocrinol Metab 1997; 82: 1362-1367.
3. Maghnie M, Aricò M, Villa A; Genovese E, Beluffi G, Severi F. MR of the hypothalamic-pituitary axis in Langerhans cell histiocytosis. Am J Neuroradiol 1992; 13: 1365-1371.
4. Maghnie M, Villa A, Aricò M, Larizza D, Pezzotta S, Beluffi G, Genovese E, Severi F. Correlation between magnetic resonance imaging of posterior pituitary and neurohypophyseal function in children with diabetes insipidus. J Clin Endocrinol Metab 1992; 74: 795-800.
5. Donadieu J, Rolon MA, Pion I, Thomas C, Doz F, Barkaoui M, Robert A, Deville A, Mazingue F, David M, Brauner R, Cabrol S, Garel C, Polak M; French LCH Study Group. Incidence of growth hormone deficiency in pediatric-onset Langerhans cell histiocytosis: efficacy and safety of growth hormone treatment. J Clin Endocrinol Metab 2004; 99: 604-609.
6. Imura H, Nakao K, Shimatsu A, Ogawa Y, Sando T, Fujisawa I, Yamabe H. Lymphocytic infundibuloneuro-hypophysitis as a cause of central diabetes insipidus. N Engl J Med 1993; 329: 683-689.
7. Leger J, Velasquez A, Garel C, Hassan M, Czernichow P. Thickened pituitary stalk on magnetic resonance imaging in children with central diabetes insipidus. J Clin Endocrinol Metab 1999; 84: 1954-1960.
8. Maghnie M, Altobelli M, di Iorgi N, Genovese E, Meloni G, Manca-Bitti ML, Cohen A, Bernasconi S. Idiopathic central diabetes insipidus is associated with abnormal blood supply to the posterior pituitary gland caused by vascular impairment of the inferior hypophyseal artery system. J Clin Endocrinol Metab 2004; 89: 1891-1896.
9. Verbalis JG, Robinson AG, Moses AM. Postoperative and post-traumatic diabetes insipidus. Front Horm Res 1985; 13: 247-265.
10. Koshimoto Y, Maeda M, Naiki H, Nakakuki K, Ishii Y. MR of pituitary metastasis in a patient with diabetes insipidus. Am J Neuroradiol 1995; 16: 971-974.
11. Kimmel DW, O'Neill BP. Systemic cancer presenting as diabetes insipidus. Clinical and radiographic features of 11 patients with a review of metastatic-induced diabetes insipidus. Cancer 1983; 52: 2355-2358.
12. Konrad D, Gartenmann M, Martin E, Schoenle EJ. Central diabetes insipidus as the first manifestation of neurosarcoidosis in a 10-years-old girl. Horm Res 2000; 54: 98-100.
13. Bullmann C, Faust M, Hoffmann A, Heppner C, Jockenhovel F, Muller-Wieland D, Krone W. Five cases with central diabetes insipidus and hypogonadism as first presentation of neurosarcoidosis. Eur J Endocrinol 2000; 142: 365-372.
14. Traggiai C, Stanhope R. Endocrinopathies associated with midline cerebral and cranial malformations. J Pediatr 2002; 140: 252-255.
15. Hansen LK, Rittig S, Robertson GL. Genetic basis of familial neurohypophyseal diabetes insipidus. Trends Endocrinol Metab 1997; 8: 363-372.
16. Willcuts MD, Felner E, White PC. Autosomal recessive familial neurohypohyseal diabetes insipidus with continued secretion of mutant weakly active vasopressin. Hum Mol Genet 1999; 8: 1303-1307.
17. Czernichow P, Pomarede R, Brauner R, Rappaport R. Neurogenic diabetes insipidus in children. Front Horm Res 1985; 13: 190-209.
18. Greger NG, Kirkland RT, Clayton GW, Kirkland JL. Central diabetes insipidus: 22 years experience. Am J Dis Child 1986; 140: 551-554.
19. Wang LC, Cohen ME, Duffner PK. Etiologies of central diabetes insipidus in children. Pediatr Neurol 1994; 11: 273-277.
20. Ghirardello S, Malattia C, Scagnelli P, Maghnie M. Current perspective on the pathogenesis of central diabetes insipidus. J Pediatr Endocrinol Metab 2005; 8: 631-645.
21. Maghnie M, Ghirardello S, De Bellis A, di Iorgi N, Ambrosini L, Secco A, De Amicis M, Tinelli C, Bellastella A, Lorini R. Idiopathic central diabetes insipidus in children and young adults is commonly associated with vasopressin-cell antibodies and markers of autoimmunity. Clin Endocrinol 2006; 65: 470-478.
22. Rauch F, Lenzner C, Nürnberg P, Frömmel C, Vetter U. A novel mutation in the coding region for neurophysin-II is associated with autosomal dominant neurohypophyseal diabetes insipidus. Clin Endocrinol 1996; 44: 45-51.
23. Friberg MA, Spiess M, Rutishauser J. Degradation of wild-type vasopressin precursor and pathogenetic mutants by the proteasome. J Biol Chem 2004; 279: 19441-19447.
24. -1→Val in the signal peptide of the arginine vasopressin/neurophysin II/copeptin precursor. J Clin Endocrinol Metab 1997; 82: 51-56.
25. Braverman LE, Mancini JP, McGoldrick DM. Hereditary and idiopathic diabetes insipidus. A case report with autopsy findings. Ann Intern Med 1965; 63: 503-508.
26. Green JR, Buchan GC, Alvord EC, Swanson AG. Hereditary and idiopathic types of diabetes insipidus. Brain 1967; 90: 707-714.
27. Christensen JH, Siggaard C, Corydon TJ, Robertson GL, Gregerson N, Bolund L, Rittig S. Differential cellular handling of defective arginine-vsopressin (AVP) prohormones in cells expressing mutations of the AVP gene associated with autosomal dominant and recessive familial neurohypophyseal diabetes insipidus. J Clin Endocrinol Metab 2004; 89: 4521-4531.
28. Ye L, Li X, Chen Y, Sun H, Wang W, Su T, Jiang L, Cui B, Ning G. Autosomal dominant neurohypophyseal diabetes insipidus with linkage to chromosome 20p13 but without mutations in the AVP-NPII gene. J Clin Endocrinol Metab 2005; 90: 4388-4393.
29. Russell TA, Ito M, Ito M, Yu RN, Martinson FA, Weiss J, Jameson JL. A murine model of autosomal dominant neurohypophyseal diabetes insipidus reveals progressive loss of vasopressin-producing neurons. J Clin Invest 2003; 112: 1697-1706.
30. Davies J, Murphy D. Autophagy in hypothalamic neurons of rats expressing a familial neurohypophyseal diabetes insipidus transgene. J Neuroendocrinol 2002; 14: 629-637.
31. Wahlstrom JT, Fowler MJ, Nicholson WE, Kovacs WJ. A novel mutation in the preprovasopressin gene identified in a kindred with autosomal dominant neurohypophyseal diabetes insipidus. J Clin Endocrinol Metab 2004; 89: 1963-1968.
32. Siggaard C, Rittig S, Corydon TJ, Andreasen PH, Jensen TG, Andresen BS, Robrtson GL, Gregersen N, Bolund L, Pederse EB. Clinical and molecular evidence of abnormal processing and trafficking of the vasopressin preprohormone in a large kindred with familial neurohypophyseal diabetes insipidus due to a signal peptide mutation. J Clin Endocrinol Metab 1999; 84: 2933-2941.
33. Ito M, Yu RN, Jameson JL. Mutant vasopressin precursors that cause autosomal dominant neurohypophyseal diabetes insipidus retain dimerization and impair the secretion of wild-type proteins. J Biol Chem 1999; 274: 9029-9037.
34. Christensen JH, Siggaard C, Corydon T, Robertson GL, Gregersen N, Bolund L, Rittig S. Impaired trafficking of mutated AVP prohormone in cells expressing rare disease genes causing autosomal dominant familial neurohypophyseal diabetes insipidus. Clin Endocrinol 2004; 60: 125-136.
35. Rutishauser J, Kopp P, Gaskill MB, Kotlar TJ, Robertson GL. Clinical and molecular analysis of three families with autosomal dominant neurohypophyseal diabetes insipidus associated with a novel and recurrent mutations in the vasopressin-neurophysis II gene. Eur J Endocrinol 2002; 146: 649-656.
36. Rittig S, Robertson GL, Siggaard C, Kovács L, Gregersen N, Nyborg J, Pedersen EB. Identification of 13 new mutations in the vasopressin-neurophysin II gene in 17 kindreds with familial autosomal dominant neurohypophyseal diabetes insipidus. Am J Med Genet 1996; 58: 107-117.
37. Skordis N, Patsalis PC, Hettinger JA, Kontou M, Herakleous E, Krishnamani MRS, Phillips JA III. A novel arginine vasopressin-neurophysin II mutation causes autosomal dominant neurohypophyseal diabetes insipidus and morphologic pituitary changes. Horm Res 2000; 53: 239-245.
38. Wolfram DJ, Wagener HP. Diabetes mellitus and simple optic atrophy among siblings: report on four cases. Mayo Clin Proc 1938; 13: 715-718.
39. Barrett TG, Bundey SE, Macleod AF. Neurodegeneration and diabetes: UK nationwide study of Wolfram (DIDMOAD) syndrome. Lancet 1995; 346: 1458-1463.
40. Inoue H, Tanizawa Y, Wasson J, Behn P, Kalidas K, Bernal-Mizrachi E, Mueckler M, Marshall H, Donis-Keller H, Crock P, Rogers D, Mikuni M, Kumashiro H, Higashi K, Sobue G, Oka Y, Permutt MA. A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome). Nat Genet 1998; 20: 143-148.
41. Strom TM, Hortnagel K, Hofmann S, Gekeler F, Scharfe C, Rabl W, Gerbitz KD, Meitinger T. Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein. Hum Mol Genet 1998; 7: 2021-2028.
42. Khanim F, Kirk J, Latif F, Barrett TG. WFS1/wolframin mutations, Wolfram syndrome, and associated diseases. Hum Mutat 2001; 17: 357-367.
43. Cryns K, Sivakumaran TA, Van den Ouweland JM, Pennings RJ, Cremers CW, Flothmann K, Young TL, Smith RJ, Lesperance MM, Van Camp G. Mutational spectrum of the WFS1 gene in Wolfram syndrome, non-syndromic hearing impairment, diabetes mellitus, and psychiatric disease. Hum Mutat 2003; 22: 275-287.
44. Bespalova IN, Van Camp G, Bom SJ, Brown DJ, Cryns K, DeWan AT, Erson AE, Flothmann K, Kunst HP, Kurnool P, Sivakumaran TA, Cremers CW, Leal SM, Burmeister M, Lesperance MM. Mutations in the Wolfram syndrome 1 gene (WFS1) are a common cause of low frequency sensorineural hearing loss. Hum Mol Genet 2001; 10: 2501-2508.
45. Hofmann S, Philbrook C, Gerbitz KD, Bauer MF. Wolfram syndrome: structural and functional analyses of mutant and wild-type wolframin, the WFS1 gene product. Hum Mol Genet 2003; 12: 2003-2012.
46. Takeda K, Inoue H, Tanizawa Y, Matsuzaki Y, Oba J, Watanabe Y, Shinoda K, Oka Y. WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain. Hum Mol Genet 2001; 10: 477-484.
47. Gabreels BA, Swaab DF, de Kleijn DP, Dean A, Seidah NG, Van de Loo JW, Van de Ven WJ, Martens GJ, Van Leeuwen FW. The vasopressin precursor is not processed in the hypothalamus of Wolfram syndrome patients with diabetes insipidus: evidence for the involvement of PC2 and 7B2. J Clin Endocrinol Metab 1998; 3: 4026-4033.
48. Osman AA, Saito M, Makepeace C, Permutt MA, Schlesinger P, Mueckler M. Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium. J Biol Chem 2003; 278: 52755-52762.
49. Welters HJ, McBain SC, Tadayyon M, Scarpello JH, Smith SA, Morgan NG. Functional effects of expression of wolframin-antisense transcripts in BRIN-BD11 beta-cells. Biochem Biophys Res Commun 2003; 307: 684-688.
50. Hofmann S, Bauer MF. Wolfram syndrome-associated mutations lead to instability and proteasomal degradation of wolframin. FEBS 2006; 580: 4000-4004.
51. Smith CJ, Crock PA, King BR, Meldrum CJ, Scott RJ. Phenotype-genotype, correlations in a series of wolfram syndrome families, Diabetes Care 2004; 27: 2003-2009.
52. Hardy C, Khanim F, Torres R, Scott-Brown M, Seller A, Poulton J, Collier D, Kirk J, Polymeropoulos M, Latif F, Barrett T. Clinical and molecular genetic analysis of 19 Wolfram syndrome kindreds demonstrating a wide spectrum of mutations in WFS1. Am J Hum Genet 1999; 65: 1279-1290.
53. Giuliano F, Bannwarth S, Monnot S, Cano A, Chabrol B, Vialettes B, Delobel B, Paquis-Flucklinger V; French Group of WS. Wolfram syndrome in French population: characterization of novel mutations and polymorphisms in the WFS1 gene. Hum Mutat 2005; 25: 99-100.
54. Domenech E, Gomez-Zaera M, Nunes V. Study of the WFS1 gene and mitochondrial DNA in Spanish Wolfram syndrome families. Clin Genet 2004, 65: 463-469.
55. Gomez-Zaera M, Strom TM, Rodriguez B, Estivill X, Meitinger T, Nunes V. Presence of a major WFS1 mutation in Spanish Wolfram syndrome pedigrees. Mol Genet Metab 2001; 72: 72-81.
56. Salih MA, Tuvemo T. Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD syndrome). A clinical study in two Sudanese families. Acta Paediatr Scand 1991; 80: 567-572.
57. van ven Ouweland JM, Cryns K, Pennings RJ, Walraven I, Janssen GM, Maassen JA, Veldhuijzen BF, Arntzenius AB, Lindhout D, Cremers CW, Van Camp G, Dikkeschei L.D. Molecular characterization of WFS1 in patients with Wolfram syndrome. J Mol Diagn 2003; 5: 88-95.
58. Medlej R, Wasson J, Baz P, Azar S, Salti I, Loiselet J, Permutt A, Halaby G. Diabetes mellitus and optic atrophy a study of Wolfram syndrome in the Lebanese population J Clin Endocrinol Metab 2004; 89: 1656-1661
59. Galluzzi P. Filosomi G, Vallone IM, Bardelli AM, Venturi C. MRI of Wolfram syndrome (DIDMOAD). Neuroradiology 1999; 41: 729-731.
60. Scolding NJ, Kellar-Wood HF, Shaw C. Shneerson JM, Antoun N. Wolfram syndrome: hereditary diabetes mellitus with brainstern and optic atrophy. Ann Neurol 1996; 39: 352-360.
61. Scherbaum WA, Bottazzo GF. Autoantibodies to vasopressin cells in idiopathic diabetes insipidus: evidence, for an autoimmune variant. Lancet 1983; i: 879-901.
62. Scherbaum WA, Czernichow P, Bottazzo GF, Doniach D. Diabetes insipidus in children. A possibile autoimmune type with vasopressin cell antibodies. J Pediatrics 1985; 107: 922-925.
63. Pivonello R, De Bellis A, Faggiano A, Di Salle F, Petretta M, Di Somma C, Perrino S, Altucci P, Bizzarro A, Bellastella A, Lombardi G, Colao A. Central diabetes insipidus and autoimmunity: relationship between the occurrence of antibodies to arginine vasopressin-secreting cells and clinical, immunological and radiological features in a large cohort of patients with central diabetes insipidus of known and unknown etiology. J Clin Endocrinol Metab 2003; 88: 1629-1636.
64. De Bellis A, Colao A, Bizzarro A, Di Salle F, Coronella C, Solimeno S, Vetrano A, Pivonello R, Pisano G, Lombardi G, Bellastella A. Longitudinal study of vasopressin-cell antibodies and of hypothalamic-pituitary region on magnetic resonance imaging in patients with autoimmume and idiopathic complete central diabetes insipidus. J Clin Endocrinol Metab 2002; 87: 3825-3829.
65. Thodou E, Asa SL, Kontogeorgos G, Kovacs K, Horvath E, Ezzat S. Clinical case seminar: Lymphocytic hypophysitis: clinicopathological findings. J Clin Endocrinol Metab 1995; 80: 2302-2311.
66. Bellastella. A, Bizzarro A, Coronella C, Bellastella G, Sinisi AA, De Bellis A. Lymphocytic hypophysitis: a rare or underestimated disease? Eur J Endocrinol 2003; 149: 363-376.
67. Ahmed SR, Aiello DP, Page R, Hopper K, Towfighi J, Santen RJ. Necrotizing infundibulo-hypophysitis: a unique syndrome of diabetes insipidus and hypopituitarism. J Clin Endocrinol Metab 1993; 76: 1499-1504.
68. De Bellis A, Colao A, Di Salle F, Coronella C, Solimeno S, Vetrano A, Pivonello R, Pisano G, Lombardi G, Bellastella A. A longitudinal study of vasopressin cell antibodies, posterior pituitary function, and magnetic resonance imaging evaluations in subclinical autoimmune central diabetes insipidus. J Clin Endocrinol Metab 1999; 84: 3047-3051.
69. Scherbaum WA, Wass JAH, Besser GM, Bottazzo GF. Doniach D. Autoinumme cranial diabetes insipidus: its association with other endocrine diseases and with histiocytosis X. Clin Endocrinol 1986; 25: 411-420.
70. Maghnie M, Genovese E, Sommaruga MG, Arico M, Locatelli D, Arbustini E, Pezzotta S, Severi F. Evolution of childhood central diabetes insipidus into panhypopituitarism with a large hypothalamic mass: is "lymphocytic infundibulo-neurohypophysitis" in children a different entity? Eur J Endocrinol 1998; 139: 635-640.
71. De Jersey J, Carmignac D, Le Tissier P, Barthlott T, Robinson I, Stockinger B. Factors affecting the susceptibility of the mouse pituitary gland to CD8 T-cell-mediated autoimmunity. Immunology 2004; 111: 254-261.
72. Grois M, Pötschger U, Prosch H, Minkov M, Arico M, Braier J, Henter J-I, Janka-Schaub G, Ladish S, Ritter J, Steiner M, Unger E, Gadner H; DALHX- and LCH and II Study Committee. Risk factors for diabetes insipidus in Langerhans cell histiocytosis. Pediatr Blood Cancer 2006; 46: 228-233.
73. Nanduri VR, Bareille P, Pritchard J, Stanhope R. Growth and endocrine disorders in multisytem Langerhans' cell histiocytosis. Clin Endocrinol (Oxf) 2000; 53: 509-515.
74. Prosch H, Grois N, Prayer D, Waldhauser F, Steiner M, Minkov M, Gadner H. Central diabetes insipidus as presenting symptom of Langerhans cell histiocytosis. Pediatr Blood Cancer 2004; 43: 594-599.
75. Grois N, Prayer D, Prosch H, Minkov M, Pötschger U, Gadner H. Course and clinical impact of magnetic resonance imaging findings in diabetes insipidus associated with Langerhans cell histiocytosis. Pediatr Blood Cancer 2004; 43: 59-65.
76. Kanagaki M, Miki Y, Takahashi JA, Shibamoto Y, Takahashi T, Ueba T, Hashimoto N, Konishi J. MRI and CT findings of neurohypophyseal germinoma. Eur J Radiol 2004; 49: 204-211.
77. Alter CA, Bilaniuk LT. Utility of magnetic resonance imaging in the evaluation of the child with central diabetes insipidus. J Pediatr Endocrinol Metab 2002; 15 (Suppl 2): 681-687.
78. Betterdorf M, Fehn M, Grulich-Henn J, Selle B, Darge K, Ludecke DK, Heinrich UE, Saeger W. Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl. Eur J Pediatr 1999; 158: 288-292.
79. Prosch H, Grois N, Bökkerink J, Prayer D, Leuschner I, Minkov M, Gadner H. Central diabetes insipidus: is it Langerhans cell histiocytosis of the pituitary stalk? A diagnostic pitfall. Pediatr Blood Cancer 2006; 46: 363-366.
80. Ghirardello S, Hopper N, Albanese A, Maghnie M. Diabetes insipidus in craniopharyngioma: postoperative management of water and electrolyte disorders. J Pediatr Endocrinol Metab 2006; 19 (Suppl 1): 413-421.
81. Hopper N, Albanese A, Ghirardello S, Maghnie M. The pre-operative endocrine assessment of craniopharyngioma. J Pediatr Endocrinol Metab 2006; 19 (Suppl 1): 325-327.
82. Seckl JR, Dunger DB, Bevan JS, Nakasu Y, Chowdrey C, Burke CW, Lightman SL. Vasopressin antagonist in early postoperative diabetes insipidus. Lancet 1990; 335: 1353-1356.
83. Shin JH, Lee HK, Choi CG, Suh DC, Kim CJ, Hong SK, Na DG. MR imaging of central diabetes insipidus: a pictorial essay. Korean J Radiol 2001; 2: 222-230.
84. Pagano L, Voso MT, Sica S, Leone G. Recovery from diabetes insipidus associated with AML after a BMT conditioning regimen including busulfan. Bone Marrow Transplant 1993; 11: 175-176.
85. Silfen ME, Garvin JH Jr, Hays AP, Starkman HS, Aranoff GS, Levine LS, Feldstein NA, Wong B, Oberfield SE. Primary central nervous system lymphoma in childhood presenting as progressive panhypopituitarism. J Pediatr Hematol Oncol 2001; 23: 130-133.
86. Capra M, Wherrett D, Weitzman S, Dirks P, Hawkins C, Bouffet E. Pituitary stalk thickening and primary central nervous system lymphoma. J Neurooncol 2004; 67: 227-231.
87. Frangoul HA, Shaw DW, Hawkins D, Park J. Diabetes insipidus as a presenting symptom of acute myelogenous leukaemia. J Pediatr Hematol Oncol 2000; 22: 457-459.
88. Spencer TS, Campellone JV, Maldonado I, Huang N, Usmani Q, Reginato AJ. Clinical and magnetic resonance imaging manifestations of neurosarcoidosis. Semin Arthritis Rheum 2004; 34: 649-661.
89. Loh KC, Green A, Dillon WP Jr, Fitzgerald PA, Weidner N, Tyrrell JB. Diabetes insipidus from neurosarcoidosis confined to the posterior pituitary. Eur J Endocrinol 1997; 137: 514-519.
90. Baumann RJ, Robertson WC Jr. Neurosarcoid presents differently in children than in adults. Pediatrics 2003; 112: 480-486.
91. Czarnecki EJ, Spickler EM. MR demonstration of Wegener granulomatosis of the infundibulum, a cause of diabetes insipidus. Am J Neuroradiol 1995; 16: 968-970.
92. Stalldecker G, Diez S, Carabelli A, Reynoso R, Rey R, Hofmann N, Beresnak A. Pituitary stalk tubercoloma. Pituitary 2002; 5: 155-162.
93. Tien R, Kucharczyk J, Kucharczyk W. MR imaging of the brain in patients with diabetes insipidus. Am J Neuroradiol 1991; 12: 533-542.
94. Agha A, Thornton E, O'Kelly P, Tormey W, Phillips J, Thompson CJ. Posterior pituitary dysfunction after traumatic brain injury. J Clin Endocrinol Metab 2004; 89: 5987-5992.
95. Smith D, McKenna K, Moore K, Tormey W, Finucane J, Phillips J, Baylis P, Thompson CJ. Baroregulation of vasopressin release in adipsic diabetes insipidus. J Clin Endocrinol Metab 2002; 87: 4564-4568.
96. Maghnie M. Central diabetes insipidus. Horm Res 2003; 59 (Suppl 1): 42-54.
97. Al-Agha AE, Thomsett MJ, Ratcliffe JF, Cotterill AM, Batch JA. Acquired central diabetes insipidus in children: a 12-year Brisbane experience. J Pediatr Child Health 2001; 37: 172-175.