Idiopathic central diabetes insipidus in children and young adults is commonly associated with vasopressin-cell antibodies and markers of autoimmunity

Clinical Endocrinology

Volumn 65, Issue 4, 2006, Pages 470-478

  Maghnie, Mohamad ^a   Ghirardello, Stefano ^b   De Bellis, Annamaria ^c   Di Iorgi, Natascia ^a   Ambrosini, Linda ^a   Secco, Andrea ^d   De Amici, Mara ^d   Tinelli, Carmine ^d   Bellastella, Antonio ^c   Lorini, Renata ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b Department of Paediatrics ^*  (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ARGIPRESSIN; AUTOANTIBODY; CELL ANTIBODY; DESMOPRESSIN ACETATE; ENDOMYSIUM ANTIBODY; GLUTAMATE DECARBOXYLASE; PARIETAL CELL ANTIBODY; PROTEIN TYROSINE PHOSPHATASE; STEROID 21 MONOOXYGENASE; THYROGLOBULIN; THYROID PEROXIDASE; THYROTROPIN RECEPTOR ANTIBODY; VASOPRESSIN;

ADOLESCENT; AGE DISTRIBUTION; ANTIBODY DETECTION; ARTICLE; AUTOIMMUNITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES INSIPIDUS; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GERM CELL TUMOR; HISTIOCYTOSIS X; HUMAN; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INFUNDIBULUM; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ADOLESCENT; ARGININE VASOPRESSIN; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHILD; DIABETES INSIPIDUS, NEUROGENIC; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOGLOBULIN G; MAGNETIC RESONANCE IMAGING; MALE; PITUITARY FUNCTION TESTS; PITUITARY GLAND; PITUITARY GLAND, ANTERIOR; PITUITARY GLAND, POSTERIOR; PITUITARY HORMONES; PROTEIN TYROSINE PHOSPHATASES; PROTEIN-TYROSINE-PHOSPHATASE; THYROID HORMONES;

EID: 33748786784     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2006.02616.x     Document Type: Article

References (27)

1. Maghnie, M., Cosi, G., Genovese, E., Manca-Bitti, M.L., Cohen, A., Zecca, S., Tinelli, C., Gallucci, M., Bernasconi, S., Boscherini, B., Severi, F. & Aricò, M. (2000) Central diabetes insipidus in children and young adults. New England Journal of Medicine, 343, 998-1007.
2. Mootha, S.L., Barkovich, A.J., Grumbach, M.M., Edwards, M.S., Gitelman, S.E., Kaplan, S.L. & Conte, F.A. (1997) Idiopathic hypothalamic diabetes insipidus, pituitary stalk thickening, and the occult intracranial germinoma in children and adolescents. Journal of Clinical Endocrinology and Metabolism, 82, 1362-1367.
3. Maghnie, M., Aricò, M., Villa, A., Genovese, E., Beluffi, G. & Severi, F. (1992) MR of the hypothalamic-pituitary axis in Langerhans cell histiocytosis. American Journal of Neuroradiology, 13, 1365-1371.
4. Maghnie, M., Villa, A., Aricò, M., Larizza, D., Pezzotta, S., Beluffi, G., Genovese, E. & Severi, F. (1992) Correlation between magnetic resonance imaging of posterior pituitary and neurohypophyseal function in children with diabetes insipidus. Journal of Clinical Endocrinology and Metabolism, 74, 795-800.
5. Donadieu, J., Rolon, M.A., Pion, I., Thomas, C., Doz, F., Barkaoui, M., Robert, A., Deville, A., Mazingue, F., David, M., Brauner, R., Cabrol, S., Garel, C. & Polak, M.; for the French LCH Study Group (2004) Incidence of growth hormone deficiency in pediatric-onset Langerhans cell histiocytosis: efficacy and safety of growth hormone treatment. Journal of Clinical Endocrinology and Metabolism, 89, 604-609.
6. Imura, H., Nakao, K., Shimatsu, A., Ogawa, Y., Sando, T., Fujisawa, I. & Yamabe, H. (1993) Lymphocytic infundibuloneurohipophysitis as a cause of central diabetes insipidus. New England Journal of Medicine, 329, 683-689.
7. Leger, J., Velasquez, A., Garel, C., Hassan, M. & Czernichow, P. (1999) Thickened pituitary stalk on magnetic resonance imaging in children with central diabetes insipidus. Journal of Clinical Endocrinology and Metabolism, 84, 1954-1960.
8. Maghnie, M., Altobelli, M., di Iorgi, N., Genovese, E., Meloni, G., Manca-Bitti, M.L., Cohen, A. & Bernasconi, S. (2004) Idiopathic central diabetes insipidus is associated with abnormal blood supply to the posterior pituitary gland caused by vascular impairment of the inferior hypophyseal artery system. Journal of Clinical Endocrinology and Metabolism, 89, 1891-1896.
9. Verbalis, J.G., Robinson, A.G. & Moses, A.M. (1985) Postoperative and post-traumatic diabetes insipidus. Frontiers of Hormone Research, 13, 247-265.
10. Hansen, L.K., Rittig, S. & Robertson, G.L. (1997) Genetic basis of familial neurohypophyseal diabetes insipidus. Trends in Endocrinology and Metabolism, 8, 363-372.
11. Willcuts, M.D., Felner, E. & White, P.C. (1999) Autosomal recessive familial neurohypohyseal diabetes insipidus with continued secretion of mutant weakly active vasopressin. Human Molecular Genetics, 8, 1303-1307.
12. Traggiai, C. & Stanhope, R. (2002) Endocrinopathies associated with midline cerebral and cranial malformations. Journal of Pediatrics, 140, 252-255.
13. Czernichow, P., Pomarede, R., Brauner, R. & Rappaport, R. (1985) Neurogenic diabetes insipidus in children. Frontiers of Hormone Research, 13, 190-209.
14. Greger, N.G., Kirkland, R.T., Clayton, G.W. & Kirkland, J.L. (1986) Central diabetes insipidus: 22 years' experience. American Journal of Diseases of Children, 140, 551-554.
15. Wang, L.C., Cohen, M.E. & Duffner, P.K. (1994) Aetiologies of central diabetes insipidus in children. Pediatric Neurology, 11, 273-277.
16. Scherbaum, W.A. & Bottazzo, G.F. (1983) Autoantibodies to vasopressin cells in idiopathic diabetes insipidus: evidence for an autoimmune variant. Lancet, 1, 897-901.
17. Scherbaum, W.A., Czernichow, P., Bottazzo, G.F. & Doniach, D. (1985) Diabetes insipidus in children. A possible autoimmune type with vasopressin cell antibodies. Journal of Pediatrics, 107, 922-925.
18. Pivonello, R., De Bellis, A., Faggiano, A., Di Salle, F., Petretta, M., Di Somma, C., Perrino, S., Altucci, P., Bizzarro, A., Bellastella, A., Lombardi, G. & Colao, A. (2003) Central diabetes insipidus and autoimmunity: relationship between the occurrence of antibodies to arginine vasopressin-secreting cells and clinical, immunological and radiological features in a large cohort of patients with central diabetes insipidus of known and unknown etiology. Journal of Clinical Endocrinology and Metabolism, 88, 1629-1636.
19. Betterle, C., Dal Pra, C., Mantero, F. & Zanchetta, R. (2002) Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction. Endocrine Reviews, 23, 327-364.
20. Maghnie, M., Uga, E., Temporini, F., Di Iorgi, N., Secco, A., Tinelli, C., Papalia, A., Casini, M.R. & Loche, S. (2005) Evaluation of adrenal function in patients with growth hormone-deficiency and hypothalamic-pituitary disorders: comparison between insulin-induced hypoglycaemia, low-dose ACTH, standard ACTH and CRH stimulation tests. European Journal of Endocrinology, 152, 735-741.
21. Maghnie, M., Genovese, E., Sommaruga, M.G., Aricò, M., Locatelli, D., Arbustini, E., Pezzotta, S. & Severi, F. (1998) Evolution of childhood central diabetes insipidus into panhypopituitarism with a large hypothalamic mass: is 'lymphocytic infundibulo-neurohypophysitis' in children a different entity? European Journal of Endocrinology, 139, 635-640.
22. Maghnie, M., Altobelli, M., Di Iorgi, N., Genovese, E., Meloni, G., Manca-Bitti, M.L., Cohen, A. & Bernasconi, S. (2004) Idiopathic central diabetes insipidus is associated with abnormal blood supply to the posterior pituitary gland caused by vascular impairment of the inferior hypophyseal artery system. Journal of Clinical Endocrinology and Metabolism, 89, 1891-1896.
23. De Bellis, A., Colao, A., Bizzarro, A., Di Salle, F., Coronella, C., Solimeno, S., Vetrano, A., Pivonello, R., Pisano, G., Lombardi, G. & Bellastella, A. (2002) Longitudinal study of vasopressin-cell antibodies and of hypothalamic-pituitary region on magnetic resonance imaging in patients with autoimmune and idiopathic complete central diabetes insipidus. Journal of Clinical Endocrinology and Metabolism, 87, 3825-3829.
24. Scherbaum, W.A., Wass, J.A.H., Besser, G.M., Bottazzo, G.F. & Doniach, D. (1986) Autoimmune cranial diabetes insipidus: its association with other endocrine diseases and with histiocytosis X. Clinical Endocrinology, 25, 411-420.
25. Cocco, C., Meloni, A., Boi, F., Pinna, G., Possenti, R., Mariotti, S. & Ferri, G.L. (2005) Median eminence dopaminergic nerve terminals: a novel target in autoimmune polyendocrine syndrome? Journal of Clinical Endocrinology and Metabolism, 90, 4108-4111.
26. De Bellis, A., Colao, A. & Di Salle, F. (1999) A longitudinal study of vasopressin cell antibodies, posterior pituitary function, and magnetic resonance imaging evaluations in subclinical autoimmune central diabetes insipidus. Journal of Clinical Endocrinology and Metabolism, 84, 3047-3051.
27. De Jersey, J., Carmignac, D., Le Tissier, P., Barthlott, T., Robinson, I. & Stockinger, B. (2004) Factors affecting the susceptibility of the mouse pituitary gland to CD8, T-cell-mediated autoimmunity. Immunology, 111, 254-261.