Wolfram syndrome-associated mutations lead to instability and proteasomal degradation of wolframin

FEBS Letters

Volumn 580, Issue 16, 2006, Pages 4000-4004

  Hofmann, Sabine ^a   Bauer, Matthias F ^a  

^a Klinikum Schwabing   (Germany)

Author keywords

Endoplasmic reticulum; Mutation; WFS1; Wolfram syndrome; Wolframin

Indexed keywords

CELL PROTEIN; PROTEASOME; UNCLASSIFIED DRUG; WOLFRAMIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME DEGRADATION; GENE EXPRESSION; GENE TARGETING; GENETIC ASSOCIATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; MISSENSE MUTATION; MOLECULAR MECHANICS; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN STABILITY; STEADY STATE; WOLFRAM SYNDROME;

ANIMALS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; FIBROBLASTS; HUMANS; MEMBRANE PROTEINS; MUTATION, MISSENSE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, QUATERNARY; RNA, MESSENGER; THERMODYNAMICS; WOLFRAM SYNDROME;

EID: 33745366067     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.06.036     Document Type: Article

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