Direct observations in vivo on the role of endothelial selectins and α4 integrin in cytokine-induced leukocyte-endothelium interactions in the mouse aorta

Circulation Research

Volumn 86, Issue 5, 2000, Pages 526-533

  Eriksson, Einar E ^a   Werr, Joachim ^a   Guo, Yancai ^a   Thoren, Peter ^a   Lindbom, Lennart ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Atherosclerosis; Cytokine; Intravital; Leukocyte; Rolling

Indexed keywords

CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTEGRIN; INTERLEUKIN 1BETA; PADGEM PROTEIN; RHODAMINE 6G; SELECTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; AORTA FLOW; ARTERY ENDOTHELIUM; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL ADHESION; CONTROLLED STUDY; IN VIVO STUDY; LEUKOCYTE ADHERENCE; LEUKOCYTE MOTILITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHEAR RATE;

EID: 0034677928     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.5.526     Document Type: Article

References (31)

1. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
2. Tervaert JW, Kallenberg CG. Cell adhesion molecules in vasculitis. Curr Opin Rheumatol. 1997;9:16-25.
3. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 1994;76:301-314.
4. Ley K, Bullard DC, Arbones ML, Bosse R, Vestweber D, Tedder TF, Beaudet AL. Sequential contribution of L- and P-selectin to leukocyte rolling in vivo. J Exp Med. 1995;181:669-675.
5. Lawrence MB, Springer TA. Neutrophils roll on E-selectin. J Immunol. 1993;151:6338-6346.
6. Ley K, Gaehtgens P, Fennie C, Singer MS, Lasky LA, Rosen SD. Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo. Blood. 1991;77:2553-2555.
7. Berlin C, Bargatze RF, Campbell JJ, von Andrian UH, Szabo MC, Hasslen SR, Nelson RD, Berg EL, Erlandsen SL, Butcher EC. Alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell. 1995;80:413-422.
8. Xie X, Raud J, Hedqvist P, Lindbom L. In vivo rolling and endothelial selectin binding of mononuclear leukocytes is distinct from that of poly-morphonuclear cells. Eur J Immunol. 1997;27:2935-2941.
9. Li H, Cybulsky MI, Gimbrone MA Jr, Libby P. An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler Thromb Vasc Biol. 1993;13:197-204.
10. Sakai A, Kume N, Nishi E, Tanoue K, Miyasaka M, Kita T. P-selectin and vascular cell adhesion molecule-1 are focally expressed in aortas of hypercholesterolemic rabbits before intimal accumulation of macrophages and T lymphocytes. Arterioscler Thromb Vasc Biol. 1997;17: 310-316.
11. Davies MJ, Gordon JL, Gearing AJ, Pigott R, Woolf N, Katz D, Kyriakopoulos A. The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis. J Pathol. 1993;171:223-229.
12. Ley K, Gaehtgens P. Endothelial, not hemodynamic, differences are responsible for preferential leukocyte rolling in rat mesenteric venules. Circ Res. 1991;69:1034-1041.
13. Mayrovitz HN, Tuma RF, Wiedeman MP. Leukocyte adherence in arterioles following extravascular tissue trauma. Microvasc Res. 1980;20: 264-274.
14. Kunkel EJ, Jung U, Ley K. TNF-α induces selectin-mediated leukocyte rolling in mouse cremaster muscle arterioles. Am J Physiol. 1997;272(pt 2):H1391-H1400.
15. Thorlacius H, Lindbom L, Raud J. Cytokine-induced leukocyte rolling in mouse cremaster muscle arterioles in P-selectin dependent. Am J Physiol. 1997;272(pt 2):H1725-H1729.
16. Lehr HA, Seemuller J, Hubner C, Menger MD, Messmer K. Oxidized LDL-induced leukocyte/endothelium interaction in vivo involves the receptor for platelet-activating factor. Arterioscler Thromb Vasc Biol. 1993;13:1013-1018.
17. Lehr HA, Frei B, Arfors KE. Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo. Proc Natl Acad Sci U S A. 1994;91:7688-7692.
18. Kunkel EJ, Ley K. Distinct phenotype of E-selectin-deficient mice: E-selectin is required for slow leukocyte rolling in vivo. Circ Res. 1996; 79:1196-1204.
19. Xie X, Hedqvist P, Lindbom L. Influence of local hemodynamics on leukocyte rolling and chemoattractant-induced firm adhesion in microvessels of the rat mesentery. Acta Physiol Scand. 1999;165: 251-258.
20. Damiano ER, Westheider J, Tozeren A, Ley K. Variation in the velocity, deformation, and adhesion energy density of leukocytes rolling within venules. Circ Res. 1996;79:1122-1130.
21. Moyer CF, Sajuthi D, Tulli H, Williams JK. Synthesis of IL-1 alpha and IL-1 beta by arterial cells in atherosclerosis. Am J Pathol. 1991;138: 951-960.
22. Lei X, Buja LM. Detection and localization of tumor necrosis factor-alpha in WHHL rabbit arteries. Atherosclerosis. 1996;23:125:81-99.
23. Kishikawa H, Shimokama T, Watanabe T. Localization of T lymphocytes and macrophages expressing IL-1, IL-2 receptor, IL-6 and TNF in human aortic intima: role of cell-mediated immunity in human atherogenesis. Virchows Archiv A Pathol Anat Histopathol. 1993;423:433-442.
24. Johnson-Tidey RR, McGregor JL, Taylor PR, Poston RN. Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques: coexpression with intercellular adhesion molecule-1. Am J Pathol. 1994;144:952-961.
25. Nakashima Y, Raines EW, Plump AS, Breslow JL, Ross R. Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse. Arterioscler Thromb Vasc Biol. 1998; 18:842-851.
26. Nakashima Y, Plump AS, Raines W, Breslow JL, Ross R. ApoE-deficient mice develop lesions of all stages of atherosclerosis throughout the arterial tree. Arterioscler Thromb Vasc Biol. 1994;14:133-140.
27. Diacovo TG, Catalina MD, Siegelman MH, von Andrian UH. Circulating activated platelets reconstitute lymphocyte homing and immunity in L-selectin-deficient mice. J Exp Med. 1998;187:197-204.
28. Jung U, Norman KE, Scharffetter-Kochanek K, Beaudet AL, Ley K. Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo. J Clin Invest. 1998;102:1526-1533.
29. Milstone DS, Fukumura D, Padgett RC, O'Donnell PE, Davis VM, Benavidez OJ, Monsky WL, Melder RJ, Jain RK, Gimbrone MA Jr. Mice lacking E-selectin show normal numbers of rolling leukocytes but reduced leukocyte stable arrest on cytokine-activated microvascular endothelium. Microcirculation. 1998;5:153-171.
30. Dong ZM, Chapman SM, Brown AA, Frenette PS, Hynes RO, Wagner DD. The combined role of P- and E-selectins in atherosclerosis. J Clin Invest. 1998;102:145-152.
31. Peter K, Nawroth P, Conradt C, Nordt T, Weiss T, Boehme M, Wunsch A, Allenberg J, Kubler W, Bode C. Circulating vascular cell adhesion molecule-1 correlates with the extent of human atherosclerosis in contrast to circulating intercellular adhesion molecule-1, E-selectin, P-selectin, and thrombomodulin. Arterioscler Thromb Vasc Biol. 1997;17:505-512.