Participation of caveolae in β1 integrin-mediated mechanotransduction

Biochemical and Biophysical Research Communications

Volumn 358, Issue 2, 2007, Pages 626-631

  Radel, Chris ^a   Carlile Klusacek, MaryEllen ^a   Rizzo, Victor ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Caveolae; Integrins; Lipid rafts; Mechanotransduction; Shear stress

Indexed keywords

BETA1 INTEGRIN; CAVEOLIN 1; CHOLESTEROL; CSK PROTEIN; MYOSIN LIGHT CHAIN; PROTEIN DERIVATIVE; SMALL INTERFERING RNA; SRC PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN DETECTION; AORTA; ARTICLE; ATTENUATION; CAVEOLA; CELL CULTURE; CELL ISOLATION; CELL MEMBRANE; CELL STRUCTURE; CELL THERAPY; CELL VACUOLE; CELLULAR DISTRIBUTION; DEPLETION; ENDOTHELIUM CELL; MECHANOTRANSDUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SHEAR STRESS; ANIMAL; CATTLE; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIGENS, CD29; CATTLE; CAVEOLAE; CAVEOLIN 1; CELLS, CULTURED; ENDOTHELIAL CELLS; MECHANOTRANSDUCTION, CELLULAR;

EID: 34248513296     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.04.179     Document Type: Article

References (29)

1. Martinac B. Mechanosensitive ion channels: molecules of mechanotransduction. J. Cell Sci. 117 (2004) 2449-2460
2. Chachisvilis M., Zhang Y.L., and Frangos J.A. G protein-coupled receptors sense fluid shear stress in endothelial cells. Proc. Natl. Acad. Sci. USA 103 (2006) 15463-15468
3. Wang Y., Miao H., Li S., Chen K.D., Li Y.S., Yuan S., Shyy J.Y., and Chien S. Interplay between integrins and FLK-1 in shear stress-induced signaling. Am. J. Physiol. Cell Physiol. 283 (2002) C1540-C1547
4. Shay-Salit A., Shushy M., Wolfovitz E., Yahav H., Breviario F., Dejana E., and Resnick N. VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cells. Proc. Natl. Acad. Sci. USA 99 (2002) 9462-9467
5. Jin Z.G., Ueba H., Tanimoto T., Lungu A.O., Frame M.D., and Berk B.C. Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase. Circ. Res. 93 (2003) 354-363
6. Osawa M., Masuda M., Kusano K., and Fujiwara K. Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecules?. J. Cell Biol. 158 (2002) 773-785
7. Tzima E., Irani-Tehrani M., Kiosses W.B., Dejana E., Schultz D.A., Engelhardt B., Cao G., DeLisser H., and Schwartz M.A. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 437 (2005) 426-431
8. Chen K.D., Li Y.S., Kim M., Li S., Yuan S., Chien S., and Shyy J.Y. Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc. J. Biol. Chem. 274 (1999) 18393-18400
9. Jalali S., del Pozo M.A., Chen K., Miao H., Li Y., Schwartz M.A., Shyy J.Y., and Chien S. Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands. Proc. Natl. Acad. Sci. USA 98 (2001) 1042-1046
10. Tzima E., Angel del Pozo M., Shattil S., Shein S., and Schwartz M. Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment. EMBO 20 (2001) 4639-4647
11. Park H., Go M.-Y., St-John P.L., Maland M.C., Lisanti M.P., Abrahamson D.R., and Jo H. Plasma membrane cholesterol is a key molecule in shear stress-dependent activation of extracellular signal-regulated kinase. J. Biol. Chem. 273 (1998) 32304-32311
12. Park H., Go Y.M., Darji R., Choi J.W., Lisanti M.P., Maland M.C., and Jo H. Caveolin-1 regulates shear stress-dependent activation of extracellular signal-regulated kinase. Am. J. Physiol. Heart Circ. Physiol. 278 (2000) H1285-H1293
13. Rizzo V., McIntosh D.P., Oh P., and Schnitzer J.E. In situ flow activates endothelial nitric oxide synthase in luminal caveolae of endothelium with rapid caveolin dissociation and calmodulin association. J. Biol. Chem. 273 (1998) 34724-34729
14. Rizzo V., Morton C., DePaola N., Schnitzer J.E., and Davies P.F. Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro. Am. J. Physiol. Heart Circ. Physiol. 285 (2003) H1720-H1729
15. Rizzo V., Sung A., Oh P., and Schnitzer J.E. Rapid mechanotransduction in situ at the luminal cell surface of vascular endothelium and its caveolae. J. Biol. Chem. 273 (1998) 26323-26329
16. Yu J., Bergaya S., Murata T., Alp I.F., Bauer M.P., Lin M.I., Drab M., Kurzchalia T.V., Stan R.V., and Sessa W.C. Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels. J. Clin. Invest. 116 (2006) 1284-1291
17. Katsumi A., Orr A.W., Tzima E., and Schwartz M.A. Integrins in mechanotransduction. J. Biol. Chem. 279 (2004) 12001-12004
18. Radel C., and Rizzo V. Integrin mechanotransduction stimulates caveolin-1 phosphorylation and recruitment of Csk to mediate actin reorganization. Am. J. Physiol. Heart Circ. Physiol. 288 (2005) H936-H945
19. M. Carlile Klusacek, V. Rizzo, Endothelial cytoskeletal reorganization in response to protease activated receptor-1 (Par1) stimulation is mediated by membrane rafts but not caveolae, Am. J. Physiol. Heart Circ. Physiol. (2007) in press, doi:10.1152/ajpheart.01044.2006.
20. Ferraro J.T., Daneshmand M., Bizios R., and Rizzo V. Depletion of plasma membrane cholesterol dampens hydrostatic pressure and shear stress-induced mechanotransduction pathways in osteoblast cultures. Am. J. Physiol. Cell Physiol. 286 (2004) C831-C839
21. Yang B., Oo T.N., and Rizzo V. Lipid rafts mediate H2O2 prosurvival effects in cultured endothelial cells. FASEB J. 20 (2006) 1501-1503
22. Wang Y., Botvinick E.L., Zhao Y., Berns M.W., Usami S., Tsien R.Y., and Chien S. Visualizing the mechanical activation of Src. Nature 434 (2005) 1040-1045
23. Aoki T., Nomura R., and Fujimoto T. Tyrosine phosphorylation of caveolin-1 in the endothelium. Exp. Cell Res. 253 (1999) 629-636
24. del Pozo M.A., Balasubramanian N., Alderson N.B., Kiosses W.B., Grande-Garcia A., Anderson R.G., and Schwartz M.A. Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization. Nat. Cell Biol. 7 (2005) 901-908
25. Parton R.G., Joggerst B., and Simons K. Regulated internalization of caveolae. J. Cell Biol. 127 (1994) 1199-1215
26. Gingras D., Gauthier F., Lamy S., Desrosiers R.R., and Beliveau R. Localization of RhoA to endothelial caveolae-enriched membrane domains. Biochem. Biophys. Res. Commun. 247 (1998) 888-893
27. Michaely P.A., Mineo C., Ying Y.S., and Anderson R.G. Polarized distribution of endogenous Rac1 and RhoA at the cell surface. J. Biol. Chem. 274 (1999) 21430-21436
28. Kawamura S., Miyamoto S., and Brown J.H. Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation. J. Biol. Chem. 278 (2003) 31111-31117
29. Sharma D.K., Brown J.C., Cheng Z., Holicky E.L., Marks D.L., and Pagano R.E. The glycosphingolipid, lactosylceramide, regulates beta1-integrin clustering and endocytosis. Cancer Res. 65 (2005) 8233-8241