Concentration-dependent interactions of the organophosphates chlorpyrifos oxon and methyl paraoxon with human recombinant acetylcholinesterase

Toxicology and Applied Pharmacology

Volumn 221, Issue 2, 2007, Pages 243-250

  Kaushik, R ^a   Rosenfeld, Clint A ^b   Sultatos, L G ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Acetylcholinesterase; Chlorpyrifos oxon; Methyl paraoxon; Organophosphorus insecticides

Indexed keywords

ACETLYTHIOCHOLINE; CHLORPYRIFOS OXON; METHYLPARAOXON; ORGANOPHOSPHATE; RECOMBINANT ACETYLCHOLINESTERASE; RECOMBINANT ENZYME; THIOCHOLINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DOSE RESPONSE; DRUG BINDING; DRUG EXPOSURE; HYDROLYSIS; MICHAELIS MENTEN KINETICS; PHOSPHORYLATION;

ACETYLCHOLINESTERASE; CATALYTIC DOMAIN; CHLORPYRIFOS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INSECTICIDES; KINETICS; PARAOXON; RECOMBINANT PROTEINS;

EID: 34248510057     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.03.013     Document Type: Article

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