The study of nasopharygeal carcinoma cell 5-8F responsiveness to negative Gram's lipopolysaccharide via TLR4-regulating signaling pathway

Progress in Biochemistry and Biophysics

Volumn 34, Issue 2, 2007, Pages 138-145

  Yang, Yi Xin ^a,b   Yang, Yun Bo ^b   Zhou, Ming ^b   Zhou, Hou De ^b   Xiang, Bo ^b   Peng, Shu Ping ^b   Li, Xiao Ling ^b   Shen, Shou Rong ^c   Li, Gui Yuan ^b  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Lipopolysaccharide; Nasopharygeal carcinoma cells; Signal transduction; Toll like receptors 4

Indexed keywords

BACTERIA (MICROORGANISMS);

EID: 34248504851     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Fearon D, Locksley R. The instructive role of innate immunity in the acquired immune response. Science, 1996, 272 (5258): 50-53
2. Martin T R. Recognition of bacterial endotoxin in the lungs. Am J Respir Cell MoI Biol, 2000, 23 (2):128-132
3. Raab-Traub N. Epstein-barr virus in the pathogenesis of NPC. Semin Cancer Biol, 2002, 12 (6): 431 -441
4. Beutler B, Rietschel E T. Innate immune sensing and its roots: the story of endotoxin. Nat Rev Immunol, 2003, 3 (2): 169-176
5. Abreu M T, Thomas L S, Arnold E T, et al. TLR signaling at the intestinal epithelial interface. J Endotoxin Res, 2003, 9 (5): 322-330
6. Zhang F X, Kirschning C J, Mancinelli R, et al. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem, 1999, 274 (12): 7611-7614
7. Jiang Z, Georgel P, Du X, et al. CD14 is required for MyD88-independent LPS signaling. Nat Immunol, 2005, 6 (6): 565-570
8. Diks S H, Richel D J, Peppelenbosch M P. LPS signal transduction: the picture is becoming more complex. Curr Top Med Chem, 2004, 4 (11): 1115-1126
9. Lee J H, Choi Y H, Kang H S, et al. An aqueous extract of Platycodi radix inhibits LPS-induced NF-kappaB nuclear translocation in human cultured airway epithelial cells. Int J Mol Med, 2004, 13(6): 843-847
10. Li J J, Westergaard C, Ghosh P, et al. Inhibitors of both nuclear factor-kappa B and activator protein-1 activation block the neoplastic transformation response. Cancer Research, 1997, 57 (16): 3569-3576
11. Kennedy M N, Mullen G E, Leiter C A, et al. A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4. J Biol Chem, 2004, 279 (33): 34698-34704
12. Smith MF Jr, Mitchell A, Li G, et al. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells. J Biol Chem, 2003, 278 (35): 32552-32560
13. Akira S, Takeda K. Toll-like receptor signaling. Nature Rev Immunol, 2004, 4 (7): 499-511
14. Coats S R, Reife R A, Bainbridge B W, et al. Porphyromonas gingivalis lipopolysaccharide antagonizes Escherichia coli lipopolysaccharide at toll-like receptor 4 in human endothelial cells. Infect Immun, 2003, 71 (12): 6799-6807
15. Underhill D M, Ozinsky A. Toll-like receptors: key mediators of microbe detection. Curr Opin Immunol, 2002, 14 (1): 103-110
16. Pugin J, Schurer M C, Leturcq D, et al. Lipopolyscchride-binding protein and soluble CD14. Proc Natl Acad Sci USA, 1993, 90 (7): 2744-2748
17. Palsson-McDermott E M, O'Neill L A. Signal transduction by the lipopolysa- ccharide receptor, Toll-like receptor-4. Immunology, 2004, 113 (2): 153-162
18. Moniek M M, Yarovinsky T O, Powers L S, et al. Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin. J Biol Chem, 2003, 278 (52): 53035-53044
19. Abreu M T, Vora P, Faure E, et al. Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J Immunol, 2001, 167 (3): 1609-1616
20. Ristimaki A. Cyclooxygenase 2: from inflammation to carcinogenesis. Novartis Found Symp, 2004, 256: 215-221
21. Karin M, Greten F R. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol, 2005, 5 (10): 749-759
22. Ballaz S, Mulshine J L. The potential contributions of chronic inflammation to lung carcinogenesis. Clin Lung Cancer, 2003, 5 (1): 46-62
23. Crowe S E. Helicobacter infection, chronic inflammation, and the development of malignancy. Curr Opin Gastroenterol, 2005, 21 (1): 32-38