Plasma testosterone, dehydroepiandrosterone sulfate, and cortisol in female patients with Huntington's disease

Neuroendocrinology Letters

Volumn 28, Issue 2, 2007, Pages 199-203

  Markianos, Manolis ^a   Panas, Marios ^a   Kalfakis, Nikos ^a   Vassilopoulos, Dimitrios ^a  

^a NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

Author keywords

Cortisol; DHEAS; Females; Huntington's disease; Testosterone

Indexed keywords

ADENINE; ANDROGEN; CYTOSINE; GUANINE; HALOPERIDOL; HYDROCORTISONE; PRASTERONE SULFATE; TESTOSTERONE;

ADULT; AGE; AGED; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMENTIA; DEPRESSION; FEMALE; GENETIC ASSOCIATION; HORMONE DETERMINATION; HUMAN; HUNTINGTON CHOREA; HYDROCORTISONE BLOOD LEVEL; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MEDICAL ASSESSMENT; POSTMENOPAUSE; PREMENOPAUSE; SYMPTOMATOLOGY; TESTOSTERONE BLOOD LEVEL; TRINUCLEOTIDE REPEAT;

EID: 34248392330     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Pavese N, Andrews TC, Brooks DJ, Ho AK, Rosser AE, Barker RA, Robbins TW, Sahakian BJ, Dunnett SB, Piccini P. Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study. Brain 2003; 126: 1127-1135.
2. Kremer HPH, Roos RAC, Dinjan GM, Bots GThAM, Bruyn GW, Hofman MA. The hypothalamic lateral tuberal nucleus and the characteristics of neuronal loss in Huntington's disease. Neurosci Lett 1991; 132: 101-104.
3. Kassubek J, Juengling FD, Kioschies T, Henkel K, Karitzky J, Kramer B, Ecker D, Andrich J, Saft C, Kraus P, Aschoff AJ, Ludolph AC, Landwehrmeyer GB. (2004). Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometric MRI study. J Neurol Neurosurg Psychiatry 2004; 75: 213-220.
4. Markianos M, Panas M, Kalfakis N, Vassilopoulos D. Plasma testosterone in male patients with Huntington's disease: relations to severity of illness and dementia. Ann Neurol 2005; 57: 520-525.
5. Papalexi E, Persson A, Bjorkqvist M, Petersen A, Woodman B, Bates GP, Sundler F, Mulder H, Brubdin P, Popovic N. Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease. EurJ Neurosci 2005; 22: 1541-1546.
6. Heuser IJ, Chase TN, Mouradian MM. The limbic-hypothalamic-pituitary-adrenal axis in Huntington's disease. Biol Psychiatry 1991; 30: 943-952.
7. Leblhuber F, Peichl M, Neubauer C, Reisecker FX, Windhager E, Maschek W. Serum dehydroepiandrosterone and cortisol measurements in Huntington's chorea. J Neurol Sci 2002; 132: 76-79.
8. Carlson LE, Sherwin BB. Relationships among cortisol (CRT), dehydroepiandrosterone-sulfate (DHEAS), and memory in a longitudinal study of healthy elderly men and women. Neurobiol Aging 1999; 20: 315-324.
9. De Bruin VMS, Vieira MCM, Rocha MNM, Viana GSB. Cortisol and dehydroepiandrosterone sulfate plasma levels and their relationship to aging, cognitive function, and dementia. Brain Cogn 50: 316-323.
10. Davis SR. Androgen replacement in women: a commentary. J Clin Endocrinol Metab 1999; 84: 1886-1891.
11. Davison SL, Bell R, Donath S, Montalto JG, Davis SR. Androgen levels in adult females: changes with age, menopause, and oophorectomy. J Clin Endocrinol Metab 2005; 90: 3847-3853.
12. Labrie F, Luu-The V, Labrie C, Belanger A, Simard J, Lin S-X, Pelletier, G. Endocrine and inreacrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocrine Rev 2003; 24: 152-182.
13. Baischer, W., Koinig, G., Hartmann, B., Huber, J., Langer, G. Hypothalamic-pituitary-gonadal axis in depressed premenopausal women: elevated blood testosterone concentrations compared to normal controls. Psychoneuroendocrinology 1995; 20: 553-559.
14. Weber B, Lewicka S, Deuschle M, Colla M, Heuser I. Testosterone, androstendione and dihydrotestosterone concentrations are elevated in female patients with major depression. Psychoneuroendocrinology 2000; 25: 765-771.
15. Barrett-Connor E, von Muhlen D, Laughlin GA, Kripke A. Endogenous levels of dehydroepiandrosterone sulfate, but not other sex hormones, are associated with depressed mood in older women: the Rancho Bernardo Study. J Amer Geriatr Soc 1999; 47: 685-691.
16. Rasmuson S, Nasman B, Carlstrom K, Olsson T. Increased levels of adrenocortical and gonadal hormones in mild to moderate Alzheimer's disease. Dement Geriatric Cogn Disord 2002; 13: 74-79.
17. Hoskin EK, Tang MX, Manly JJ, Mayeux R. Elevated sex-hormone binding globulin in elderly women with Alzheimer's disease. Neurobiol Aging 2004; 25: 141-147.
18. Cohrs S, Roher C, Jordan W, Meier A, Huether G, Wuttke W, Ruther E, Rodenbeck A. The atypical antipsychotics olanzapine and quetiapine, but not haloperidol, reduce ACTH and cortisol secretion in healthy subjects. Psychopharmacology 2006; 185: 11-18.
19. Markianos M, Hatzimanolis J, Lykouras L. Gonadal axis hormones in male schizophrenic patients during treatment with haloperidol and after switch to risperidone. Psychopharmacology 1999; 143: 270-272.
20. Warner JP, Barron LH, Brock DJH. A new polymerase chain reaction (PCR) assay for the trinucleotide repeat that is unstable and expanded on Huntington's Disease chromosomes. Mol Cell Probes 1993; 7: 235-239.
21. Huntington Study Group. Unified Huntington's Disease Rating Scale. Reliability and consistency. Mov Disord 1996; 11: 136-142.
22. Shoulson I, Fahn S. Huntington's disease: clinical care and evaluation. Neurology 1979; 29: 1-3.
23. Yaffe K, Ettinger B, Pressman A, Seely D, Whooley M, Schaefer C, Cummings S. Neuropsychiatric function and dehydroepiandrosterone sulfate in elderly women: a prospective study. Biol Psychiatry 1998; 43: 694-700.
24. Berr C, Lafont S, Debuire B, Dartigues J-F, Baulieu E-E. Relationships of dehydroepiandrosterone sulfate in the elderly with functional, psychological, and mental status, and short-term mortality: a French community-based study. Proc Natl Acad Sci USA 1996; 93: 13410-13415.
25. Bloch M, Schmidt PJ, Danaceau MA, Adams LF, Rubinow DR. Dehydroepiandrosterone treatment of midlife dysthymia. Biol Psychiatry 1999; 45: 1533-1541.
26. Baulieu, E-E. Steroid hormones in the brain: several mechanisms. In: Fuxe K, Gustafson JA, Wetterberg L, editors. Steroid hormone regulation of the brain. New York: Pergamon; 1981. p. 3-14.
27. Majewska MD, Demirgoren S, Spivak CE, London ED. The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor. Brain Res 1990; 526: 143-146.
28. Glass M, Dragunow M, Fault RL. The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease. Neuroscience 2000; 97: 505-519.