Impaired permeabilty to Ins(1,4,5)P3 in a mutant connexin underlies recessive hereditary deafness

Nature Cell Biology

Volumn 7, Issue 1, 2005, Pages 63-69

  Beltramello, Martina ^a   Piazza, Valeria ^a   Bukauskas, Feliksas F ^b   Pozzan, Tullio ^a,c   Mammano, Fabio ^a,c  

^a VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CONNEXIN 26; INOSITOL 1,4,5 TRISPHOSPHATE; LEUCINE; LUCIFER YELLOW; MUTANT PROTEIN; VALINE; CALCIUM; GAP JUNCTION PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COMMUNICATION; CELL FUNCTION; CONDUCTANCE; CONTROLLED STUDY; CORTI ORGAN; GAP JUNCTION; GENE MUTATION; GENETIC DISORDER; HEARING IMPAIRMENT; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; ION PERMEABILITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; SYNCYTIUM; TISSUE REGENERATION; WILD TYPE; ACTIVE TRANSPORT; ANIMAL; CALCIUM SIGNALING; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE POTENTIAL; CYTOLOGY; DRUG EFFECT; GENETICS; HAIR CELL; METABOLISM; MUTATION; NEWBORN; ORGAN CULTURE TECHNIQUE; PATHOPHYSIOLOGY; RECESSIVE GENE; SECOND MESSENGER; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL TRANSPORT, ACTIVE; CALCIUM; CALCIUM SIGNALING; CELL COMMUNICATION; CELL MEMBRANE PERMEABILITY; CONNEXINS; DEAFNESS; GAP JUNCTIONS; GENES, RECESSIVE; HAIR CELLS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; LABYRINTH SUPPORTING CELLS; MEMBRANE POTENTIALS; MUTATION; ORGAN CULTURE TECHNIQUES; ORGAN OF CORTI; RATS; RATS, SPRAGUE-DAWLEY; SECOND MESSENGER SYSTEMS;

EID: 12344304163     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1205     Document Type: Article

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