-
1
-
-
0024516672
-
IL-3-dependent growth of basophil-like cells and mastlike cells from human bone marrow
-
Kirshenbaum AS, Goff JP, Dreskin SC, Irani AM, Schwartz LB, Metcalfe DD. IL-3-dependent growth of basophil-like cells and mastlike cells from human bone marrow. J Immunol. 1989;142:2424-2429.
-
(1989)
J Immunol
, vol.142
, pp. 2424-2429
-
-
Kirshenbaum, A.S.1
Goff, J.P.2
Dreskin, S.C.3
Irani, A.M.4
Schwartz, L.B.5
Metcalfe, D.D.6
-
2
-
-
0026073372
-
Demonstration of the origin of human mast cells from CD34+ bone marrow progenitor cells
-
Kirshenbaum AS, Kessler SW, Goff JP, Metcalfe DD. Demonstration of the origin of human mast cells from CD34+ bone marrow progenitor cells. J Immunol. 1991;146:1410-1415.
-
(1991)
J Immunol
, vol.146
, pp. 1410-1415
-
-
Kirshenbaum, A.S.1
Kessler, S.W.2
Goff, J.P.3
Metcalfe, D.D.4
-
3
-
-
0033215406
-
Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13)
-
Kirshenbaum AS, Goff JP, Semere T, Foster B, Scott LM, Metcalfe DD. Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13). Blood. 1999;94: 2333-2342.
-
(1999)
Blood
, vol.94
, pp. 2333-2342
-
-
Kirshenbaum, A.S.1
Goff, J.P.2
Semere, T.3
Foster, B.4
Scott, L.M.5
Metcalfe, D.D.6
-
4
-
-
0027519639
-
Monocytes do not make mast cells when cultured in the presence of SCF: Characterization of the circulating mast cell progenitor as a c-kit+, CD34+, Ly-, CD14-, CD17-, colony-forming cell
-
Agis H, Willheim M, Sperr WR, et al. Monocytes do not make mast cells when cultured in the presence of SCF: characterization of the circulating mast cell progenitor as a c-kit+, CD34+, Ly-, CD14-, CD17-, colony-forming cell. J Immunol. 1993;151:4221-4227.
-
(1993)
J Immunol
, vol.151
, pp. 4221-4227
-
-
Agis, H.1
Willheim, M.2
Sperr, W.R.3
-
6
-
-
0027530391
-
Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand
-
Mitsui H, Furitsu T, Dvorak AM, et al. Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand. Proc Natl Acad Sci U S A. 1993;90:735-739.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 735-739
-
-
Mitsui, H.1
Furitsu, T.2
Dvorak, A.M.3
-
7
-
-
0027049982
-
Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells
-
Irani AM, Nilsson G, Miettinen U, et al. Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells. Blood. 1992;80:3009-3021.
-
(1992)
Blood
, vol.80
, pp. 3009-3021
-
-
Irani, A.M.1
Nilsson, G.2
Miettinen, U.3
-
8
-
-
0026801434
-
Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture
-
Valent P, Spanblochl E, Sperr WR, et al. Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture. Blood, 1992; 80:2237-2245.
-
(1992)
Blood
, vol.80
, pp. 2237-2245
-
-
Valent, P.1
Spanblochl, E.2
Sperr, W.R.3
-
9
-
-
0029987331
-
Flow cytometric analysis of mast cells from normal and pathological human bone marrow samples: Identification and enumeration
-
Orfao A, Escribano L, Villarrubia J, et al. Flow cytometric analysis of mast cells from normal and pathological human bone marrow samples: identification and enumeration. Am J Pathol. 1996;149:1493-1499.
-
(1996)
Am J Pathol
, vol.149
, pp. 1493-1499
-
-
Orfao, A.1
Escribano, L.2
Villarrubia, J.3
-
10
-
-
18144449057
-
Immunophenotypic characterization of human bone marrow mast cells: A flow cytometric study of normal and pathological bone marrow samples
-
Escribano L, Orfao A, Villarrubia J, et al. Immunophenotypic characterization of human bone marrow mast cells: a flow cytometric study of normal and pathological bone marrow samples. Anal Cell Pathol. 1998;16:151-159.
-
(1998)
Anal Cell Pathol
, vol.16
, pp. 151-159
-
-
Escribano, L.1
Orfao, A.2
Villarrubia, J.3
-
11
-
-
33747519112
-
Mast cell mediators in allergic inflammation and mastocytosis
-
Castells M. Mast cell mediators in allergic inflammation and mastocytosis. Immunol Allergy Clin North Am. 2006;26:465-485.
-
(2006)
Immunol Allergy Clin North Am
, vol.26
, pp. 465-485
-
-
Castells, M.1
-
12
-
-
0020511371
-
Systemic mastocytosis: Extracutaneous manifestations
-
Brunning RD, McKenna RW, Rosai J, Parkin JL, Risdall R. Systemic mastocytosis: extracutaneous manifestations. Am J Surg Pathol. 1983;7:425-438.
-
(1983)
Am J Surg Pathol
, vol.7
, pp. 425-438
-
-
Brunning, R.D.1
McKenna, R.W.2
Rosai, J.3
Parkin, J.L.4
Risdall, R.5
-
14
-
-
0034766591
-
Bone marrow mast cell morphologic features and hematopoietic dyspoiesis in systemic mast cell disease
-
Stevens EC, Rosenthal NS. Bone marrow mast cell morphologic features and hematopoietic dyspoiesis in systemic mast cell disease. Am J Clin Pathol. 2001;116:177-182.
-
(2001)
Am J Clin Pathol
, vol.116
, pp. 177-182
-
-
Stevens, E.C.1
Rosenthal, N.S.2
-
15
-
-
0032523149
-
Indolent systemic mast cell disease in adults: Immunophenotypic characterization of bone marrow mast cells and its diagnostic implications
-
Escribano L, Orfao A, Diaz-Agustin B, et al. Indolent systemic mast cell disease in adults: immunophenotypic characterization of bone marrow mast cells and its diagnostic implications. Blood. 1998;91:2731-2736.
-
(1998)
Blood
, vol.91
, pp. 2731-2736
-
-
Escribano, L.1
Orfao, A.2
Diaz-Agustin, B.3
-
16
-
-
0035895078
-
Expression, epitope analysis, and functional role of the LFA-2 antigen detectable on neoplastic mast cells
-
Schernthaner GH, Jordan JH, Ghannadan M, et al. Expression, epitope analysis, and functional role of the LFA-2 antigen detectable on neoplastic mast cells. Blood. 2001;98:3784-3792.
-
(2001)
Blood
, vol.98
, pp. 3784-3792
-
-
Schernthaner, G.H.1
Jordan, J.H.2
Ghannadan, M.3
-
17
-
-
2942596256
-
Bone marrow mast cell immunophenotyping in adults with mast cell disease: A prospective study of 33 patients
-
Pardanani A, Kimlinger T, Reeder T, Li CY, Tefferi A. Bone marrow mast cell immunophenotyping in adults with mast cell disease: a prospective study of 33 patients. Leuk Res. 2004;28:777-783.
-
(2004)
Leuk Res
, vol.28
, pp. 777-783
-
-
Pardanani, A.1
Kimlinger, T.2
Reeder, T.3
Li, C.Y.4
Tefferi, A.5
-
18
-
-
0034987361
-
Immunohistochemical properties of bone marrow mast cells in systemic mastocytosis: Evidence for expression of CD2, CD117/Kit, and bcl-x(L)
-
Jordan JH, Walchshofer S, Jurecka W, et al. Immunohistochemical properties of bone marrow mast cells in systemic mastocytosis: evidence for expression of CD2, CD117/Kit, and bcl-x(L). Hum Pathol. 2001;32:545-552.
-
(2001)
Hum Pathol
, vol.32
, pp. 545-552
-
-
Jordan, J.H.1
Walchshofer, S.2
Jurecka, W.3
-
19
-
-
5044230101
-
CD25 indicates the neoplastic phenotype of mast cells: A novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens
-
Sotlar K, Horny HP, Simonitsch I, et al. CD25 indicates the neoplastic phenotype of mast cells: a novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens. Am J Surg Pathol. 2004;28:1319-1325.
-
(2004)
Am J Surg Pathol
, vol.28
, pp. 1319-1325
-
-
Sotlar, K.1
Horny, H.P.2
Simonitsch, I.3
-
20
-
-
0034983045
-
Diagnostic criteria and classification of mastocytosis: A consensus proposal
-
Valent P, Horny HP, Escribano L, et al. Diagnostic criteria and classification of mastocytosis: a consensus proposal. Leuk Res. 2001;25:603-625.
-
(2001)
Leuk Res
, vol.25
, pp. 603-625
-
-
Valent, P.1
Horny, H.P.2
Escribano, L.3
-
21
-
-
33749368009
-
KIT mutation in mast cells and other bone marrow haematopoietic cell lineages in systemic mast cell disorders: A prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients
-
Garcia-Montero AC, Jara-Acevedo M, Teodosio C, et al. KIT mutation in mast cells and other bone marrow haematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients. Blood. 2006;108:2366-2372.
-
(2006)
Blood
, vol.108
, pp. 2366-2372
-
-
Garcia-Montero, A.C.1
Jara-Acevedo, M.2
Teodosio, C.3
-
22
-
-
33745042240
-
Pathogenesis, clinical features, and treatment advances in mastocytosis
-
Pardanani A, Akin C, Valent P. Pathogenesis, clinical features, and treatment advances in mastocytosis. Best Pract Res Clin Haematol. 2006;19:595-615.
-
(2006)
Best Pract Res Clin Haematol
, vol.19
, pp. 595-615
-
-
Pardanani, A.1
Akin, C.2
Valent, P.3
-
23
-
-
0027359443
-
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product
-
Furitsu T, Tsujimura T, Tono T, et al. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest. 1993;92: 1736-1744.
-
(1993)
J Clin Invest
, vol.92
, pp. 1736-1744
-
-
Furitsu, T.1
Tsujimura, T.2
Tono, T.3
-
24
-
-
0028856070
-
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder
-
Nagata H, Worobec AS, Oh CK, et al. Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. Proc Natl Acad Sci U S A. 1995;92:10560-10564.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 10560-10564
-
-
Nagata, H.1
Worobec, A.S.2
Oh, C.K.3
-
25
-
-
13044305857
-
Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis
-
Longley BJ Jr, Metcalfe DD, Tharp M, et al. Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. Proc Natl Acad Sci U S A. 1999;96:1609-1614.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 1609-1614
-
-
Longley Jr, B.J.1
Metcalfe, D.D.2
Tharp, M.3
-
26
-
-
0033749308
-
Mast cell disease associated with acute myeloid leukemia: Detection of a new c-kit mutation Asp816His
-
Pullarkat VA, Pullarkat ST, Calverley DC, Brynes RK. Mast cell disease associated with acute myeloid leukemia: detection of a new c-kit mutation Asp816His. Am J Hematol. 2000;65:30-7309.
-
(2000)
Am J Hematol
, vol.65
, pp. 30-7309
-
-
Pullarkat, V.A.1
Pullarkat, S.T.2
Calverley, D.C.3
Brynes, R.K.4
-
27
-
-
0031039992
-
A new c-kit mutation in a case of aggressive mast cell disease
-
Pignon JM, Giraudier S, Duquesnoy P, et al. A new c-kit mutation in a case of aggressive mast cell disease. Br J Haematol. 1997;96:374-376.
-
(1997)
Br J Haematol
, vol.96
, pp. 374-376
-
-
Pignon, J.M.1
Giraudier, S.2
Duquesnoy, P.3
-
28
-
-
24144503371
-
Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis
-
Hartmann K, Wardelmann E, Ma Y, et al. Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis. Gastroenterology. 2005;129:1042-1046.
-
(2005)
Gastroenterology
, vol.129
, pp. 1042-1046
-
-
Hartmann, K.1
Wardelmann, E.2
Ma, Y.3
-
29
-
-
19444371824
-
A germline mutation in KIT in familial diffuse cutaneous mastocytosis
-
Tang X, Boxer M, Drummond A, Ogston P, Hodgins M, Burden AD. A germline mutation in KIT in familial diffuse cutaneous mastocytosis. J Med Genet. 2004;41:e88.
-
(2004)
J Med Genet
, vol.41
-
-
Tang, X.1
Boxer, M.2
Drummond, A.3
Ogston, P.4
Hodgins, M.5
Burden, A.D.6
-
30
-
-
1842579440
-
A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib
-
Akin C, Fumo G, Yavuz AS, Lipsky PE, Neckers L, Metcalfe DD. A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib. Blood. 2004;103:3222-3225.
-
(2004)
Blood
, vol.103
, pp. 3222-3225
-
-
Akin, C.1
Fumo, G.2
Yavuz, A.S.3
Lipsky, P.E.4
Neckers, L.5
Metcalfe, D.D.6
-
31
-
-
0035425217
-
Germline mutation in the juxta-membrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa
-
Beghini A, Tibiletti MG, Roversi G, et al. Germline mutation in the juxta-membrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa. Cancer. 2001;92:657-662.
-
(2001)
Cancer
, vol.92
, pp. 657-662
-
-
Beghini, A.1
Tibiletti, M.G.2
Roversi, G.3
-
32
-
-
32844455834
-
A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy
-
Zhang LY, Smith ML, Schultheis B, et al. A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy. Leuk Res. 2006;30:373-378.
-
(2006)
Leuk Res
, vol.30
, pp. 373-378
-
-
Zhang, L.Y.1
Smith, M.L.2
Schultheis, B.3
-
33
-
-
33748615147
-
Molecular diagnosis of mast cell disorders: A paper from the 2005 William Beaumont Hospital Symposium on Molecular Pathology
-
Akin C. Molecular diagnosis of mast cell disorders: a paper from the 2005 William Beaumont Hospital Symposium on Molecular Pathology. J Mol Diagn. 2006;8:412-419.
-
(2006)
J Mol Diagn
, vol.8
, pp. 412-419
-
-
Akin, C.1
-
34
-
-
34248139457
-
-
Valent PHH, Li CY, Longley JB, et al. Mastocytosis (mast cell disease). In: Pathology and Genetics of Tumours of the Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001:291-302. World Health Organization Classification of Tumours; 1.
-
Valent PHH, Li CY, Longley JB, et al. Mastocytosis (mast cell disease). In: Pathology and Genetics of Tumours of the Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press; 2001:291-302. World Health Organization Classification of Tumours; vol 1.
-
-
-
-
35
-
-
0036202127
-
Cutaneous mastocytosis - clinical heterogeneity
-
Hartmann K, Henz BM. Cutaneous mastocytosis - clinical heterogeneity. Int Arch Allergy Immunol. 2002;127:143-146.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 143-146
-
-
Hartmann, K.1
Henz, B.M.2
-
36
-
-
0036206786
-
Classification of cutaneous mastocytosis: A modified consensus proposal
-
author reply 485-486
-
Hartmann K, Henz BM. Classification of cutaneous mastocytosis: a modified consensus proposal. Leuk Res. 2002;26:483-484; author reply 485-486.
-
(2002)
Leuk Res
, vol.26
, pp. 483-484
-
-
Hartmann, K.1
Henz, B.M.2
-
37
-
-
0033946285
-
Mastocytosis and the skin
-
vi
-
Soter NA. Mastocytosis and the skin. Hematol Oncol Clin North Am. 2000; 14:537-555, vi.
-
(2000)
Hematol Oncol Clin North Am
, vol.14
, pp. 537-555
-
-
Soter, N.A.1
-
40
-
-
0036242354
-
Comparison of mastocytosis with onset in children and adults
-
Middelkamp Hup MA, Heide R, Tank B, Mulder PG, Oranje AP. Comparison of mastocytosis with onset in children and adults. J Eur Acad Dermatol Venereol. 2002;16:115-120.
-
(2002)
J Eur Acad Dermatol Venereol
, vol.16
, pp. 115-120
-
-
Middelkamp Hup, M.A.1
Heide, R.2
Tank, B.3
Mulder, P.G.4
Oranje, A.P.5
-
41
-
-
0023837831
-
Bone marrow findings in adult patients with urticaria pigmentosa
-
Czarnetzki BM, Kolde G, Schoemann A, Urbanitz S, Urbanitz D. Bone marrow findings in adult patients with urticaria pigmentosa. J Am Acad Dermatol. 1988;18:45-51.
-
(1988)
J Am Acad Dermatol
, vol.18
, pp. 45-51
-
-
Czarnetzki, B.M.1
Kolde, G.2
Schoemann, A.3
Urbanitz, S.4
Urbanitz, D.5
-
42
-
-
0036204671
-
Mastocytosis: Mediator-related signs and symptoms
-
Castells M, Austen KF. Mastocytosis: mediator-related signs and symptoms. Int Arch Allergy Immunol. 2002;127:147-152.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 147-152
-
-
Castells, M.1
Austen, K.F.2
-
43
-
-
0023764931
-
Gastrointestinal dysfunction in systemic mastocytosis: A prospective study
-
Cherner JA, Jensen RT, Dubois A, O'Dorisio TM, Gardner JD, Metcalfe DD. Gastrointestinal dysfunction in systemic mastocytosis: a prospective study. Gastroenterology. 1988;95:657-667.
-
(1988)
Gastroenterology
, vol.95
, pp. 657-667
-
-
Cherner, J.A.1
Jensen, R.T.2
Dubois, A.3
O'Dorisio, T.M.4
Gardner, J.D.5
Metcalfe, D.D.6
-
44
-
-
0024320886
-
Gastric acid secretion in systemic mastocytosis
-
Cherner JA. Gastric acid secretion in systemic mastocytosis. N Engl J Med. 1989;320:1562.
-
(1989)
N Engl J Med
, vol.320
, pp. 1562
-
-
Cherner, J.A.1
-
45
-
-
0025921179
-
Systemic mastocytosis: Retrospective review of a decade's clinical experience at the Brigham and Women's Hospital
-
discussion 13S-14S
-
Horan RF, Austen KF. Systemic mastocytosis: retrospective review of a decade's clinical experience at the Brigham and Women's Hospital. J Invest Dermatol. 1991;96:5S-13S; discussion 13S-14S.
-
(1991)
J Invest Dermatol
, vol.96
-
-
Horan, R.F.1
Austen, K.F.2
-
46
-
-
0026322938
-
Hematologic manifestations of systemic mast cell disease: A prospective study of laboratory and morphologic features and their relation to prognosis
-
Lawrence JB, Friedman BS, Travis WD, Chinchilli VM, Metcalfe DD, Gralnick HR. Hematologic manifestations of systemic mast cell disease: a prospective study of laboratory and morphologic features and their relation to prognosis. Am J Med. 1991;91:612-624.
-
(1991)
Am J Med
, vol.91
, pp. 612-624
-
-
Lawrence, J.B.1
Friedman, B.S.2
Travis, W.D.3
Chinchilli, V.M.4
Metcalfe, D.D.5
Gralnick, H.R.6
-
47
-
-
0024271215
-
Systemic mast cell disease: Analysis of 58 cases and literature review
-
Travis WD, Li CY, Bergstralh EJ, Yam LT, Swee RG. Systemic mast cell disease: analysis of 58 cases and literature review. Medicine (Baltimore). 1988; 67:345-368.
-
(1988)
Medicine (Baltimore)
, vol.67
, pp. 345-368
-
-
Travis, W.D.1
Li, C.Y.2
Bergstralh, E.J.3
Yam, L.T.4
Swee, R.G.5
-
49
-
-
0030814553
-
Systemic mast cell disease (mastocytosis). General aspects and histopathological diagnosis
-
Horny HP, Ruck P, Krober S, Kaiserling E. Systemic mast cell disease (mastocytosis). General aspects and histopathological diagnosis. Histol Histopathol. 1997;12:1081-1089.
-
(1997)
Histol Histopathol
, vol.12
, pp. 1081-1089
-
-
Horny, H.P.1
Ruck, P.2
Krober, S.3
Kaiserling, E.4
-
50
-
-
0018294638
-
Mast cells and mast cell neoplasia: A review
-
Lennert K, Parwaresch MR. Mast cells and mast cell neoplasia: a review. Histopathology. 1979;3:349-365.
-
(1979)
Histopathology
, vol.3
, pp. 349-365
-
-
Lennert, K.1
Parwaresch, M.R.2
-
51
-
-
0034982081
-
Diagnosis of mastocytosis: Value of cytochemistry and immunohistochemistry
-
Li CY. Diagnosis of mastocytosis: value of cytochemistry and immunohistochemistry. Leuk Res. 2001;25:537-541.
-
(2001)
Leuk Res
, vol.25
, pp. 537-541
-
-
Li, C.Y.1
-
52
-
-
0031682307
-
Diagnostic value of immunostaining for tryptase in patients with mastocytosis
-
Horny HP, Sillaber C, Menke D, et al. Diagnostic value of immunostaining for tryptase in patients with mastocytosis. Am J Surg Pathol. 1998;22:1132-1140.
-
(1998)
Am J Surg Pathol
, vol.22
, pp. 1132-1140
-
-
Horny, H.P.1
Sillaber, C.2
Menke, D.3
-
53
-
-
0036207693
-
Histopathological and immunohistochemical aspects of mastocytosis
-
Horny HP, Valent P. Histopathological and immunohistochemical aspects of mastocytosis. Int Arch Allergy Immunol. 2002;127:115-117.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 115-117
-
-
Horny, H.P.1
Valent, P.2
-
54
-
-
2642581620
-
Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases: A histopathological challenge
-
Horny HP, Sotlar K, Sperr WR, Valent P. Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases: a histopathological challenge. J Clin Pathol. 2004;57:604-608.
-
(2004)
J Clin Pathol
, vol.57
, pp. 604-608
-
-
Horny, H.P.1
Sotlar, K.2
Sperr, W.R.3
Valent, P.4
-
55
-
-
0034983239
-
Morphologic properties of neoplastic mast cells: Delineation of stages of maturation and implication for cytological grading of mastocytosis
-
Sperr WR, Escribano L, Jordan JH, et al. Morphologic properties of neoplastic mast cells: delineation of stages of maturation and implication for cytological grading of mastocytosis. Leuk Res. 2001;25:529-536.
-
(2001)
Leuk Res
, vol.25
, pp. 529-536
-
-
Sperr, W.R.1
Escribano, L.2
Jordan, J.H.3
-
56
-
-
33747332572
-
Flow cytometric analysis of normal and neoplastic mast cells: Role in diagnosis and follow-up of mast cell disease
-
Escribano L, Garcia Montero AC, Nunez R, Orfao A. Flow cytometric analysis of normal and neoplastic mast cells: role in diagnosis and follow-up of mast cell disease. Immunol Allergy Clin North Am. 2006;26:535-547.
-
(2006)
Immunol Allergy Clin North Am
, vol.26
, pp. 535-547
-
-
Escribano, L.1
Garcia Montero, A.C.2
Nunez, R.3
Orfao, A.4
-
57
-
-
0036202126
-
Abnormal expression of CD antigens in mastocytosis
-
Escribano L, Diaz-Agustin B, Nunez R, Prados A, Rodriguez R, Orfao A. Abnormal expression of CD antigens in mastocytosis. Int Arch Allergy Immunol. 2002;127:127-132.
-
(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 127-132
-
-
Escribano, L.1
Diaz-Agustin, B.2
Nunez, R.3
Prados, A.4
Rodriguez, R.5
Orfao, A.6
-
58
-
-
0030900209
-
Sequential immunophenotypic analysis of mast cells in a case of systemic mast cell disease evolving to a mast cell leukemia
-
Escribano L, Orfao A, Villarrubia J, et al. Sequential immunophenotypic analysis of mast cells in a case of systemic mast cell disease evolving to a mast cell leukemia. Cytometry. 1997;30:98-102.
-
(1997)
Cytometry
, vol.30
, pp. 98-102
-
-
Escribano, L.1
Orfao, A.2
Villarrubia, J.3
-
59
-
-
2342532361
-
Immunophenotypic normalization of aberrant mast cells accompanies histological remission in imatinib-treated patients with eosinophilia-associated mastocytosis
-
Elliott MA, Pardanani A, Li CY, Tefferi A. Immunophenotypic normalization of aberrant mast cells accompanies histological remission in imatinib-treated patients with eosinophilia-associated mastocytosis. Leukemia. 2004;18:1027-1029.
-
(2004)
Leukemia
, vol.18
, pp. 1027-1029
-
-
Elliott, M.A.1
Pardanani, A.2
Li, C.Y.3
Tefferi, A.4
-
60
-
-
12144286558
-
Immunophenotypic analysis of mast cells in mastocytosis: When and how to do it. Proposals of the Spanish Network on Mastocytosis (REMA)
-
Escribano L, Diaz-Agustin B, Lopez A, et al. Immunophenotypic analysis of mast cells in mastocytosis: when and how to do it. Proposals of the Spanish Network on Mastocytosis (REMA). Cytometry B Clin Cytom. 2004;58:1-8.
-
(2004)
Cytometry B Clin Cytom
, vol.58
, pp. 1-8
-
-
Escribano, L.1
Diaz-Agustin, B.2
Lopez, A.3
-
61
-
-
0037275446
-
Overexpression of complement receptors and related antigens on the surface of bone marrow mast cells in patients with systemic mastocytosis
-
Nunez-Lopez R, Escribano L, Schernthaner GH, et al. Overexpression of complement receptors and related antigens on the surface of bone marrow mast cells in patients with systemic mastocytosis. Br J Haematol. 2003;120:257-265.
-
(2003)
Br J Haematol
, vol.120
, pp. 257-265
-
-
Nunez-Lopez, R.1
Escribano, L.2
Schernthaner, G.H.3
-
62
-
-
0032820883
-
The CD69 early activation molecule is overexpressed in human bone marrow mast cells from adults with indolent systemic mast cell disease
-
Diaz-Agustin B, Escribano L, Bravo P, et al. The CD69 early activation molecule is overexpressed in human bone marrow mast cells from adults with indolent systemic mast cell disease. Br J Haematol. 1999;106:400-405.
-
(1999)
Br J Haematol
, vol.106
, pp. 400-405
-
-
Diaz-Agustin, B.1
Escribano, L.2
Bravo, P.3
-
63
-
-
0542420329
-
Human bone marrow mast cells from indolent systemic mast cell disease constitutively express increased amounts of the CD63 protein on their surface
-
Escribano L, Orfao A, Diaz Agustin B, et al. Human bone marrow mast cells from indolent systemic mast cell disease constitutively express increased amounts of the CD63 protein on their surface. Cytometry. 1998;34:223-228.
-
(1998)
Cytometry
, vol.34
, pp. 223-228
-
-
Escribano, L.1
Orfao, A.2
Diaz Agustin, B.3
-
64
-
-
0023262466
-
Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis
-
Schwartz LB, Metcalfe DD, Miller JS, Earl H, Sullivan T. Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis. N Engl J Med. 1987;316:1622-1626.
-
(1987)
N Engl J Med
, vol.316
, pp. 1622-1626
-
-
Schwartz, L.B.1
Metcalfe, D.D.2
Miller, J.S.3
Earl, H.4
Sullivan, T.5
-
65
-
-
33747331674
-
Diagnostic value of tryptase in anaphylaxis and mastocytosis
-
Schwartz LB. Diagnostic value of tryptase in anaphylaxis and mastocytosis. Immunol Allergy Clin North Am. 2006;26:451-463.
-
(2006)
Immunol Allergy Clin North Am
, vol.26
, pp. 451-463
-
-
Schwartz, L.B.1
-
66
-
-
0038527434
-
Tryptase precursors are preferentially and spontaneously released, whereas mature tryptase is retained by HMC-1 cells, Mono-Mac-6 cells, and human skin-derived mast cells
-
Schwartz LB, Min HK, Ren S, et al. Tryptase precursors are preferentially and spontaneously released, whereas mature tryptase is retained by HMC-1 cells, Mono-Mac-6 cells, and human skin-derived mast cells. J Immunol. 2003;170: 5667-5673.
-
(2003)
J Immunol
, vol.170
, pp. 5667-5673
-
-
Schwartz, L.B.1
Min, H.K.2
Ren, S.3
-
67
-
-
0028881815
-
The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis
-
Schwartz LB, Sakai K, Bradford TR, et al. The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis. J Clin Invest. 1995;96:2702-2710.
-
(1995)
J Clin Invest
, vol.96
, pp. 2702-2710
-
-
Schwartz, L.B.1
Sakai, K.2
Bradford, T.R.3
-
68
-
-
0035496941
-
Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia
-
Sperr WR, Jordan JH, Baghestanian M, et al. Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia. Blood. 2001;98:2200-2209.
-
(2001)
Blood
, vol.98
, pp. 2200-2209
-
-
Sperr, W.R.1
Jordan, J.H.2
Baghestanian, M.3
-
69
-
-
0036891221
-
Tryptase a novel biochemical marker of acute myeloid leukemia
-
Sperr WR, Hauswirth AW, Valent P. Tryptase a novel biochemical marker of acute myeloid leukemia. Leuk Lymphoma. 2002;43:2257-2261.
-
(2002)
Leuk Lymphoma
, vol.43
, pp. 2257-2261
-
-
Sperr, W.R.1
Hauswirth, A.W.2
Valent, P.3
-
70
-
-
0036253402
-
Serum tryptase measurements in patients with myelodysplastic syndromes
-
Sperr WR, Stehberger B, Wimazal F et al. Serum tryptase measurements in patients with myelodysplastic syndromes. Leuk Lymphoma. 2002;43:1097-1105.
-
(2002)
Leuk Lymphoma
, vol.43
, pp. 1097-1105
-
-
Sperr, W.R.1
Stehberger, B.2
Wimazal, F.3
-
71
-
-
0035889122
-
Detection of tryptase in cytoplasmic granules of basophils in patients with chronic myeloid leukemia and other myeloid neoplasms
-
Samorapoompichit P, Kiener HP, Schernthaner GH, et al. Detection of tryptase in cytoplasmic granules of basophils in patients with chronic myeloid leukemia and other myeloid neoplasms. Blood. 2001;98:2580-2583.
-
(2001)
Blood
, vol.98
, pp. 2580-2583
-
-
Samorapoompichit, P.1
Kiener, H.P.2
Schernthaner, G.H.3
-
72
-
-
0036843231
-
Detection of c-kit point mutation Asp-816→Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia
-
Sotlar K, Fridrich C, Mall A, et al. Detection of c-kit point mutation Asp-816→Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia. Leuk Res. 2002;26:979-984.
-
(2002)
Leuk Res
, vol.26
, pp. 979-984
-
-
Sotlar, K.1
Fridrich, C.2
Mall, A.3
-
73
-
-
0038341142
-
Eosinophils are derived from the neoplastic clone in patients with systemic mastocytosis and eosinophilia
-
Pardanani A, Reeder T, Li CY, Tefferi A. Eosinophils are derived from the neoplastic clone in patients with systemic mastocytosis and eosinophilia. Leuk Res. 2003;27:883-885.
-
(2003)
Leuk Res
, vol.27
, pp. 883-885
-
-
Pardanani, A.1
Reeder, T.2
Li, C.Y.3
Tefferi, A.4
-
74
-
-
0037100321
-
Evidence for the involvement of a hematopoietic progenitor cell in systemic mastocytosis from single-cell analysis of mutations in the c-kit gene
-
Yavuz AS, Lipsky PE, Yavuz S, Metcalfe DD, Akin C. Evidence for the involvement of a hematopoietic progenitor cell in systemic mastocytosis from single-cell analysis of mutations in the c-kit gene. Blood. 2002;100:661-665.
-
(2002)
Blood
, vol.100
, pp. 661-665
-
-
Yavuz, A.S.1
Lipsky, P.E.2
Yavuz, S.3
Metcalfe, D.D.4
Akin, C.5
-
75
-
-
15544385343
-
Detection of an activating c-kit mutation by real-time PCR in patients with anaphylaxis
-
Lawley W, Hird H, Mallinder P, et al. Detection of an activating c-kit mutation by real-time PCR in patients with anaphylaxis. Mutat Res. 2005;572:1-13.
-
(2005)
Mutat Res
, vol.572
, pp. 1-13
-
-
Lawley, W.1
Hird, H.2
Mallinder, P.3
-
76
-
-
0344643427
-
One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes
-
Sotlar K, Escribano L, Landt O, et al. One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes. Am J Pathol. 2003;162:737-746.
-
(2003)
Am J Pathol
, vol.162
, pp. 737-746
-
-
Sotlar, K.1
Escribano, L.2
Landt, O.3
-
78
-
-
0026322938
-
Hematologic manifestations of systemic mast cell disease: A prospective study of laboratory and morphologic features and their relation to prognosis
-
Lawrence JB, Friedman BS, Travis WD, Chinchilli VM, Metcalfe DD, Gralnick HR. Hematologic manifestations of systemic mast cell disease: a prospective study of laboratory and morphologic features and their relation to prognosis. Am J Med. 1991;91:612-624.
-
(1991)
Am J Med
, vol.91
, pp. 612-624
-
-
Lawrence, J.B.1
Friedman, B.S.2
Travis, W.D.3
Chinchilli, V.M.4
Metcalfe, D.D.5
Gralnick, H.R.6
-
79
-
-
0024271215
-
Systemic mast cell disease: Analysis of 58 cases and literature review
-
Travis WD, Li CY, Bergstralh EJ, Yam LT, Swee RG. Systemic mast cell disease: analysis of 58 cases and literature review. Medicine (Baltimore). 1988; 67:345-368.
-
(1988)
Medicine (Baltimore)
, vol.67
, pp. 345-368
-
-
Travis, W.D.1
Li, C.Y.2
Bergstralh, E.J.3
Yam, L.T.4
Swee, R.G.5
-
80
-
-
0036843907
-
Systemic mast cell disease without associated hematologic disorder: A combined retrospective and prospective study
-
Pardanani A, Baek JY, Li CY, Butterfield JH, Tefferi A. Systemic mast cell disease without associated hematologic disorder: a combined retrospective and prospective study. Mayo Clin Proc. 2002;77:1169-1175.
-
(2002)
Mayo Clin Proc
, vol.77
, pp. 1169-1175
-
-
Pardanani, A.1
Baek, J.Y.2
Li, C.Y.3
Butterfield, J.H.4
Tefferi, A.5
-
81
-
-
8644263305
-
FIP1L1-PDGFRA fusion: Prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia
-
Pardanani A, Brockman SR, Paternoster SF, et al. FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia. Blood. 2004;104:3038-3045.
-
(2004)
Blood
, vol.104
, pp. 3038-3045
-
-
Pardanani, A.1
Brockman, S.R.2
Paternoster, S.F.3
-
82
-
-
0344987881
-
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
-
Cools J, DeAngelo DJ, Gotlib J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med. 2003;348:1201-1214.
-
(2003)
N Engl J Med
, vol.348
, pp. 1201-1214
-
-
Cools, J.1
DeAngelo, D.J.2
Gotlib, J.3
-
83
-
-
33644868101
-
Multilineage involvement of the fusion gene in patients with FIP1L1/PDGFRA-positive hypereosinophilic syndrome
-
Robyn J, Lemery S, McCoy JP, et al. Multilineage involvement of the fusion gene in patients with FIP1L1/PDGFRA-positive hypereosinophilic syndrome. Br J Haematol. 2006;132:286-292.
-
(2006)
Br J Haematol
, vol.132
, pp. 286-292
-
-
Robyn, J.1
Lemery, S.2
McCoy, J.P.3
-
84
-
-
0038792233
-
Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness
-
Klion AD, Noel P, Akin C, et al. Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness. Blood. 2003;101:4660-4666.
-
(2003)
Blood
, vol.101
, pp. 4660-4666
-
-
Klion, A.D.1
Noel, P.2
Akin, C.3
-
85
-
-
0942276859
-
Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome
-
Klion AD, Robyn J, Akin C, et al. Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome. Blood. 2004;103:473-478.
-
(2004)
Blood
, vol.103
, pp. 473-478
-
-
Klion, A.D.1
Robyn, J.2
Akin, C.3
-
86
-
-
10744228486
-
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib therapy
-
Pardanani A, Ketterling RP, Brockman SR, et al. CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib therapy. Blood. 2003;102:3093-3096.
-
(2003)
Blood
, vol.102
, pp. 3093-3096
-
-
Pardanani, A.1
Ketterling, R.P.2
Brockman, S.R.3
-
87
-
-
10744228486
-
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy
-
Pardanani A, Ketterling RP, Brockman SR, et al. CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy. Blood. 2003; 102:3093-3096.
-
(2003)
Blood
, vol.102
, pp. 3093-3096
-
-
Pardanani, A.1
Ketterling, R.P.2
Brockman, S.R.3
-
88
-
-
4243139496
-
Relationship between idiopathic hypereosinophilic syndrome, eo-sinophilic leukemia, and systemic mastocytosis
-
Bain BJ. Relationship between idiopathic hypereosinophilic syndrome, eo-sinophilic leukemia, and systemic mastocytosis. Am J Hematol. 2004;77:82-85.
-
(2004)
Am J Hematol
, vol.77
, pp. 82-85
-
-
Bain, B.J.1
-
89
-
-
0034992599
-
Myelomastocytic overlap syndromes: Biology, criteria, and relationship to mastocytosis
-
Valent P, Sperr WR, Samorapoompichit P, et al. Myelomastocytic overlap syndromes: biology, criteria, and relationship to mastocytosis. Leuk Res. 2001; 25:595-602.
-
(2001)
Leuk Res
, vol.25
, pp. 595-602
-
-
Valent, P.1
Sperr, W.R.2
Samorapoompichit, P.3
-
90
-
-
0346880065
-
Clinical, genetic, and therapeutic insights into systemic mast cell disease
-
Tefferi A, Pardanani A. Clinical, genetic, and therapeutic insights into systemic mast cell disease. Curr Opin Hematol. 2004;11:58-64.
-
(2004)
Curr Opin Hematol
, vol.11
, pp. 58-64
-
-
Tefferi, A.1
Pardanani, A.2
-
91
-
-
4544357034
-
Systemic mastocytosis: Current concepts and treatment advances
-
Tefferi A, Pardanani A. Systemic mastocytosis: current concepts and treatment advances. Curr Hematol Rep. 2004;3:197-202.
-
(2004)
Curr Hematol Rep
, vol.3
, pp. 197-202
-
-
Tefferi, A.1
Pardanani, A.2
-
92
-
-
0000124580
-
The natural course of urticaria pigmentosa: Analysis and follow-up of 112 cases
-
Caplan RM. The natural course of urticaria pigmentosa: analysis and follow-up of 112 cases. Arch Dermatol. 1963;87:146-157.
-
(1963)
Arch Dermatol
, vol.87
, pp. 146-157
-
-
Caplan, R.M.1
-
94
-
-
0020683503
-
Intervention with epinephrine in hypotension associated with mastocytosis
-
Turk J, Oates JA, Roberts LJ II. Intervention with epinephrine in hypotension associated with mastocytosis. J Allergy Clin Immunol. 1983;71:189-192.
-
(1983)
J Allergy Clin Immunol
, vol.71
, pp. 189-192
-
-
Turk, J.1
Oates, J.A.2
Roberts II, L.J.3
-
95
-
-
0036454699
-
Treatment of adult systemic mastocytosis with interferon-alpha: Results of a multicentre phase II trial on 20 patients
-
Casassus P, Caillat-Vigneron N, Martin A, et al. Treatment of adult systemic mastocytosis with interferon-alpha: results of a multicentre phase II trial on 20 patients. Br J Haematol. 2002;119:1090-1097.
-
(2002)
Br J Haematol
, vol.119
, pp. 1090-1097
-
-
Casassus, P.1
Caillat-Vigneron, N.2
Martin, A.3
-
96
-
-
21344466047
-
Interferon treatment for hypereosinophilic syndromes and systemic mastocytosis
-
Butterfield JH. Interferon treatment for hypereosinophilic syndromes and systemic mastocytosis. Acta Haematol. 2005;114:26-40.
-
(2005)
Acta Haematol
, vol.114
, pp. 26-40
-
-
Butterfield, J.H.1
-
100
-
-
33747336257
-
KIT mutations in mastocytosis and their potential as therapeutic targets
-
Gotlib J. KIT mutations in mastocytosis and their potential as therapeutic targets. Immunol Allergy Clin North Am. 2006;26:575-592.
-
(2006)
Immunol Allergy Clin North Am
, vol.26
, pp. 575-592
-
-
Gotlib, J.1
-
101
-
-
0036493872
-
The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations
-
Ma Y, Zeng S, Metcalfe DD, et al. The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations. Blood. 2002;99:1741-1744.
-
(2002)
Blood
, vol.99
, pp. 1741-1744
-
-
Ma, Y.1
Zeng, S.2
Metcalfe, D.D.3
-
102
-
-
0043169405
-
Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit
-
Akin C, Brockow K, D'Ambrosio C, et al. Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit. Exp Hematol. 2003;31:686-692.
-
(2003)
Exp Hematol
, vol.31
, pp. 686-692
-
-
Akin, C.1
Brockow, K.2
D'Ambrosio, C.3
-
103
-
-
0041656424
-
Imatinib for systemic mast-cell disease
-
Pardanani A, Elliott M, Reeder T, et al. Imatinib for systemic mast-cell disease. Lancet. 2003;362:535-536.
-
(2003)
Lancet
, vol.362
, pp. 535-536
-
-
Pardanani, A.1
Elliott, M.2
Reeder, T.3
-
104
-
-
1042277752
-
Inefficacy of imatinib-mesylate in sporadic, aggressive systemic mastocytosis
-
Musto P, Falcone A, Sanpaolo G, Bodenizza C, Carella AM. Inefficacy of imatinib-mesylate in sporadic, aggressive systemic mastocytosis. Leuk Res. 2004; 28:421-422.
-
(2004)
Leuk Res
, vol.28
, pp. 421-422
-
-
Musto, P.1
Falcone, A.2
Sanpaolo, G.3
Bodenizza, C.4
Carella, A.M.5
-
105
-
-
33646532818
-
FIP1L1-PDGFRA in eosinophilic disorders: Prevalence in routine clinical practice, long-term experience with imatinib therapy, and a critical review of the literature
-
Pardanani A, Ketterling RP, Li CY, et al. FIP1L1-PDGFRA in eosinophilic disorders: prevalence in routine clinical practice, long-term experience with imatinib therapy, and a critical review of the literature. Leuk Res. 2006;30:965-970.
-
(2006)
Leuk Res
, vol.30
, pp. 965-970
-
-
Pardanani, A.1
Ketterling, R.P.2
Li, C.Y.3
-
106
-
-
0038731316
-
Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant
-
Frost MJ, Ferrao PT, Hughes TP, Ashman LK. Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant. Mol Cancer Ther. 2002; 1:1115-1124.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1115-1124
-
-
Frost, M.J.1
Ferrao, P.T.2
Hughes, T.P.3
Ashman, L.K.4
-
107
-
-
33645687784
-
Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in the majority of patients with systemic mastocytosis
-
Shah NP, Lee FY, Luo R, Jiang Y, Donker M, Akin C. Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in the majority of patients with systemic mastocytosis. Blood. 2006;108:286-291.
-
(2006)
Blood
, vol.108
, pp. 286-291
-
-
Shah, N.P.1
Lee, F.Y.2
Luo, R.3
Jiang, Y.4
Donker, M.5
Akin, C.6
-
108
-
-
31544459272
-
Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
-
Schittenhelm MM, Shiraga S, Schroeder A, et al. Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies. Cancer Res. 2006;66:473-481.
-
(2006)
Cancer Res
, vol.66
, pp. 473-481
-
-
Schittenhelm, M.M.1
Shiraga, S.2
Schroeder, A.3
-
109
-
-
0036595143
-
Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412
-
Weisberg E, Boulton C, Kelly LM, et al. Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412. Cancer Cell. 2002;1:433-443.
-
(2002)
Cancer Cell
, vol.1
, pp. 433-443
-
-
Weisberg, E.1
Boulton, C.2
Kelly, L.M.3
-
110
-
-
19944427559
-
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
-
Stone RM, DeAngelo DJ, Klimek V, et al. Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood. 2005;105:54-60.
-
(2005)
Blood
, vol.105
, pp. 54-60
-
-
Stone, R.M.1
DeAngelo, D.J.2
Klimek, V.3
-
111
-
-
5144234541
-
PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder
-
Chen J, Deangelo DJ, Kutok JL, et al. PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder. Proc Natl Acad Sci U S A. 2004;101: 14479-14484.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14479-14484
-
-
Chen, J.1
Deangelo, D.J.2
Kutok, J.L.3
-
112
-
-
0142119964
-
PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRalpha-induced myeloproliferative disease
-
Cools J, Stover EH, Boulton CL, et al. PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRalpha-induced myeloproliferative disease. Cancer Cell. 2003;3:459-469.
-
(2003)
Cancer Cell
, vol.3
, pp. 459-469
-
-
Cools, J.1
Stover, E.H.2
Boulton, C.L.3
-
113
-
-
27144506215
-
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation
-
Gotlib J, Berube C, Growney JD, et al. Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. Blood. 2005;106:2865-2870.
-
(2005)
Blood
, vol.106
, pp. 2865-2870
-
-
Gotlib, J.1
Berube, C.2
Growney, J.D.3
-
114
-
-
22044443112
-
In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit
-
Corbin AS, Demehri S, Griswold IJ, et al. In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit. Blood. 2005;106:227-234.
-
(2005)
Blood
, vol.106
, pp. 227-234
-
-
Corbin, A.S.1
Demehri, S.2
Griswold, I.J.3
-
115
-
-
9444258068
-
Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970
-
Corbin AS, Griswold IJ, La Rosee P, et al. Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970. Blood. 2004;104:3754-3757.
-
(2004)
Blood
, vol.104
, pp. 3754-3757
-
-
Corbin, A.S.1
Griswold, I.J.2
La Rosee, P.3
-
116
-
-
0037100281
-
Inhibition of constitutively active forms of mutant kit by multitargeted indolinone tyrosine kinase inhibitors
-
Liao AT, Chien MB, Shenoy N, et al. Inhibition of constitutively active forms of mutant kit by multitargeted indolinone tyrosine kinase inhibitors. Blood. 2002;100:585-593.
-
(2002)
Blood
, vol.100
, pp. 585-593
-
-
Liao, A.T.1
Chien, M.B.2
Shenoy, N.3
-
117
-
-
26944458584
-
The systemic mastocytosis-specific activating cKit mutation D816V can be inhibited by the tyrosine kinase inhibitor AMN107
-
von Bubnoff N, Gorantla SH, Kancha RK, Lordick F, Peschel C, Duyster J. The systemic mastocytosis-specific activating cKit mutation D816V can be inhibited by the tyrosine kinase inhibitor AMN107. Leukemia. 2005;19:1670-1671.
-
(2005)
Leukemia
, vol.19
, pp. 1670-1671
-
-
von Bubnoff, N.1
Gorantla, S.H.2
Kancha, R.K.3
Lordick, F.4
Peschel, C.5
Duyster, J.6
-
118
-
-
23844477497
-
Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930
-
Petti F, Thelemann A, Kahler J, et al. Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930. Mol Cancer Ther. 2005;4:1186-1197.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1186-1197
-
-
Petti, F.1
Thelemann, A.2
Kahler, J.3
-
119
-
-
31544481378
-
OSI-930: A novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models
-
Garton AJ, Crew AP, Franklin M, et al. OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models. Cancer Res. 2006;66:1015-1024.
-
(2006)
Cancer Res
, vol.66
, pp. 1015-1024
-
-
Garton, A.J.1
Crew, A.P.2
Franklin, M.3
|