Exposure in utero to 2,2′,3,3′,4,6′-hexachlorobiphenyl (PCB 132) impairs sperm function and alters testicular apoptosis-related gene expression in rat offspring

Toxicology and Applied Pharmacology

Volumn 221, Issue 1, 2007, Pages 68-75

  Hsu, Ping Chi ^a   Pan, Min Hsiung ^a   Li, Lih Ann ^b   Chen, Cheng Jung ^a   Tsai, Shinn Shyong ^c   Guo, Yueliang Leon ^d  

^a NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c NATIONAL PINGTUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis related genes; Caspase activation; Male reproduction; Polychlorinated biphenyls (PCBs); Prenatal exposure; Sperm dysfunction

Indexed keywords

2,2',3,3',4,6' HEXACHLOROBIPHENYL; CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; POLYCHLORINATED BIPHENYL DERIVATIVE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; EMBRYOTOXICITY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; ENZYME INHIBITION; EPIDIDYMIS TAIL; FEMALE; GENE EXPRESSION; GESTATION PERIOD; HISTOPATHOLOGY; MALE; MALE FERTILITY; MALE GENITAL SYSTEM; NONHUMAN; ORGAN WEIGHT; PRENATAL EXPOSURE; RAT; REPRODUCTIVE TOXICITY; SPERMATOZOON ABNORMALITY; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD95; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; INJECTIONS, INTRAPERITONEAL; MALE; MODELS, BIOLOGICAL; POLYCHLORINATED BIPHENYLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPERMATOZOA; TESTIS; TUMOR SUPPRESSOR PROTEIN P53;

RATTUS;

EID: 34248211838     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.01.027     Document Type: Article

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