Ablation of central nervous system progenitor cells in transgenic rats using bacterial nitroreductase system

Journal of Neuroscience Research

Volumn 85, Issue 6, 2007, Pages 1183-1193

  Kwak, Seung P ^a   Malberg, Jessica E ^b   Howland, David S ^a   Cheng, Ke Yi ^b   Su, Jianying ^b   She, Yin ^b   Fennell, Myles ^b   Ghavami, Afshin ^b  

^a CHDI   (United States)

^b PFIZER INC   (United States)

Author keywords

Ablation; BrdU; Cerebellum; E. coli nitroreductase (NTR); GFP; Green fluorescent protein; Hippocampus; Progenitor cells; Rat; Stem cell; Transgenic

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; BROXURIDINE; ENHANCED GREEN FLUORESCENT PROTEIN; NESTIN; NITROREDUCTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATAXIA; BRAIN DEVELOPMENT; BRAIN REGION; BRAIN SIZE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CEREBELLUM DEGENERATION; CONTROLLED STUDY; CYTOTOXICITY; DENTATE GYRUS; DNA SYNTHESIS; GENE EXPRESSION; HIPPOCAMPUS; IN VITRO STUDY; LATERAL BRAIN VENTRICLE; MALE; NEURAL STEM CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR FUNCTION; STEM CELL; TRANSGENIC RAT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANIMALS, NEWBORN; ANTINEOPLASTIC AGENTS; AZIRIDINES; BEHAVIOR, ANIMAL; BROMODEOXYURIDINE; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSHOCK; ESCHERICHIA COLI PROTEINS; GREEN FLUORESCENT PROTEINS; HUMANS; INJECTIONS, INTRAVENTRICULAR; INTERMEDIATE FILAMENT PROTEINS; NERVE TISSUE PROTEINS; NITROREDUCTASES; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS; TIME FACTORS;

EID: 34248207164     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21223     Document Type: Article

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