메뉴 건너뛰기




Volumn 4, Issue 5, 2007, Pages 277-287

Mechanisms of Disease: Update on the molecular etiology and fundamentals of parenteral nutrition associated cholestasis

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM; AMINOTRANSFERASE; ANTIBIOTIC AGENT; BILIRUBIN; ENDOTOXIN; LIPID; MANGANESE; METRONIDAZOLE; OXIDIZING AGENT; TAURINE; TAUROURSODEOXYCHOLIC ACID; URSODEOXYCHOLIC ACID;

EID: 34248199431     PISSN: 17434378     EISSN: 17434386     Source Type: Journal    
DOI: 10.1038/ncpgasthep0796     Document Type: Review
Times cited : (150)

References (86)
  • 1
    • 0035409498 scopus 로고    scopus 로고
    • The development of TPN: An interview with pioneer surgical nutritionist Jonathan E Rhoads, MD [Interview by Carolyn T Spencer and Charlene Compher]
    • Rhoads JE (2001) The development of TPN: An interview with pioneer surgical nutritionist Jonathan E Rhoads, MD [Interview by Carolyn T Spencer and Charlene Compher]. J Am Diet Assoc 101: 747-750
    • (2001) J Am Diet Assoc , vol.101 , pp. 747-750
    • Rhoads, J.E.1
  • 2
    • 0347087304 scopus 로고    scopus 로고
    • The impact of nursing practice on the history and effectiveness of total parenteral nutrition
    • Guenter P et al. (2004) The impact of nursing practice on the history and effectiveness of total parenteral nutrition. JPEN J Parenter Enteral Nutr 28: 54-59
    • (2004) JPEN J Parenter Enteral Nutr , vol.28 , pp. 54-59
    • Guenter, P.1
  • 3
    • 0019585868 scopus 로고    scopus 로고
    • [No authors listed] (1981) Nutrition classics. Surgery, 64, 1968. Long-term total parenteral nutrition with growth, development, and positive nitrogen balance: Stanley J. Dudrick, Douglas W. Wilmore, Harry M. Vars, Jonathan E. Rhoads. Nutr Rev 39: 278-281
    • [No authors listed] (1981) Nutrition classics. Surgery, Volume 64, 1968. Long-term total parenteral nutrition with growth, development, and positive nitrogen balance: Stanley J. Dudrick, Douglas W. Wilmore, Harry M. Vars, Jonathan E. Rhoads. Nutr Rev 39: 278-281
  • 4
    • 0016434320 scopus 로고
    • Cholestasis in immature newborn infants: Is parenteral alimentation responsible?
    • Rager R and Finegold MJ (1975) Cholestasis in immature newborn infants: is parenteral alimentation responsible? J Pediatr 86: 264-269
    • (1975) J Pediatr , vol.86 , pp. 264-269
    • Rager, R.1    Finegold, M.J.2
  • 5
    • 0020109942 scopus 로고
    • Total parenteral alimentation and cholestasis
    • Finegold MJ (1982) Total parenteral alimentation and cholestasis. Am J Clin Pathol 77: 378-379
    • (1982) Am J Clin Pathol , vol.77 , pp. 378-379
    • Finegold, M.J.1
  • 6
    • 0024377138 scopus 로고
    • An analysis of factors contributing to the development of total parenteral nutrition-induced cholestasis
    • Drongowski RA and Coran AG (1989) An analysis of factors contributing to the development of total parenteral nutrition-induced cholestasis. JPEN J Parenter Enteral Nutr 13: 586-589
    • (1989) JPEN J Parenter Enteral Nutr , vol.13 , pp. 586-589
    • Drongowski, R.A.1    Coran, A.G.2
  • 8
    • 0031985884 scopus 로고    scopus 로고
    • Liver complications of pediatric parenteral nutrition - epidemiology
    • Kelly DA (1998) Liver complications of pediatric parenteral nutrition - epidemiology. Nutrition 14: 153-157
    • (1998) Nutrition , vol.14 , pp. 153-157
    • Kelly, D.A.1
  • 9
    • 0030875593 scopus 로고    scopus 로고
    • Parenteral nutrition-associated cholestasis
    • Teitelbaum DH (1997) Parenteral nutrition-associated cholestasis. Curr Opin Pediatr 9: 270-275
    • (1997) Curr Opin Pediatr , vol.9 , pp. 270-275
    • Teitelbaum, D.H.1
  • 10
    • 32144435080 scopus 로고    scopus 로고
    • Intestinal failure-associated liver disease: What do we know today?
    • Kelly DA (2006) Intestinal failure-associated liver disease: What do we know today? Gastroenterology 130 (Suppl 1): S70-S77
    • (2006) Gastroenterology , vol.130 , Issue.SUPPL. 1
    • Kelly, D.A.1
  • 11
    • 0018419788 scopus 로고
    • Intrahepatic cholestasis associated with parenteral nutrition in premature infants
    • Beale EF et al. (1979) Intrahepatic cholestasis associated with parenteral nutrition in premature infants. Pediatrics 64: 342-347
    • (1979) Pediatrics , vol.64 , pp. 342-347
    • Beale, E.F.1
  • 12
    • 0036153858 scopus 로고    scopus 로고
    • Parenteral nutrition-associated liver complications in children
    • Btaiche IF and Khalidi N (2002) Parenteral nutrition-associated liver complications in children. Pharmacotherapy 22: 188-211
    • (2002) Pharmacotherapy , vol.22 , pp. 188-211
    • Btaiche, I.F.1    Khalidi, N.2
  • 13
    • 0029976277 scopus 로고    scopus 로고
    • Parenteral nutrition-related cholestasis in postsurgical neonates: Multivariate analysis of risk factors
    • Beath SV et al. (1996) Parenteral nutrition-related cholestasis in postsurgical neonates: Multivariate analysis of risk factors. J Pediatr Surg 31: 604-606
    • (1996) J Pediatr Surg , vol.31 , pp. 604-606
    • Beath, S.V.1
  • 14
    • 15244346919 scopus 로고    scopus 로고
    • Total parenteral nutrition induced liver pathology: An autopsy series of 24 newborn cases
    • Zambrano E et al. (2004) Total parenteral nutrition induced liver pathology: An autopsy series of 24 newborn cases. Pediatr Dev Pathol 7: 425-432
    • (2004) Pediatr Dev Pathol , vol.7 , pp. 425-432
    • Zambrano, E.1
  • 15
    • 0028379997 scopus 로고
    • Total parenteral nutrition: A histopathologic analysis of the liver changes in 20 children
    • Mullick FG et al. (1994) Total parenteral nutrition: A histopathologic analysis of the liver changes in 20 children. Mod Pathol 7: 190-194
    • (1994) Mod Pathol , vol.7 , pp. 190-194
    • Mullick, F.G.1
  • 16
    • 0019471876 scopus 로고
    • Pediatric total parenteral nutrition: Liver histopathology
    • Cohen C and Olsen MM (1981) Pediatric total parenteral nutrition: Liver histopathology. Arch Pathol Lab Med 105: 152-156
    • (1981) Arch Pathol Lab Med , vol.105 , pp. 152-156
    • Cohen, C.1    Olsen, M.M.2
  • 17
    • 0026742326 scopus 로고
    • Long-term parenteral nutrition in children: Liver and gallbladder disease
    • Colomb V et al. (1992) Long-term parenteral nutrition in children: liver and gallbladder disease. Transplant Proc 24: 1054-1055
    • (1992) Transplant Proc , vol.24 , pp. 1054-1055
    • Colomb, V.1
  • 18
    • 0034199756 scopus 로고    scopus 로고
    • New developments in total parenteral nutrition for children
    • Shulman RJ (2000) New developments in total parenteral nutrition for children. Curr Gastroenterol Rep 2: 253-258
    • (2000) Curr Gastroenterol Rep , vol.2 , pp. 253-258
    • Shulman, R.J.1
  • 19
    • 0022485347 scopus 로고
    • Total parenteral nutrition-related cholestasis in infants
    • Bell RL et al. (1986) Total parenteral nutrition-related cholestasis in infants. JPEN J Parenter Enteral Nutr 10: 356-359
    • (1986) JPEN J Parenter Enteral Nutr , vol.10 , pp. 356-359
    • Bell, R.L.1
  • 20
    • 0020607713 scopus 로고
    • Immaturity of the enterohepatic circulation in early life: Factors predisposing to "physiologic" maldigestion and cholestasis
    • Balistreri WF et al. (1983) Immaturity of the enterohepatic circulation in early life: Factors predisposing to "physiologic" maldigestion and cholestasis. J Pediatr Gastroenterol Nutr 2 346-354
    • (1983) J Pediatr Gastroenterol Nutr , vol.2 , pp. 346-354
    • Balistreri, W.F.1
  • 21
    • 0020607714 scopus 로고
    • Diversity of bile acids in the fetus and newborn infant
    • Lester R et al. (1983) Diversity of bile acids in the fetus and newborn infant. J Pediatr Gastroenterol Nutr 2: 355-364
    • (1983) J Pediatr Gastroenterol Nutr , vol.2 , pp. 355-364
    • Lester, R.1
  • 22
    • 0018378157 scopus 로고
    • Intestinal absorption of bile selts: Immature development in the neonate
    • de Belle RC et al. (1979) Intestinal absorption of bile selts: immature development in the neonate. J Pediatr 94: 472-476
    • (1979) J Pediatr , vol.94 , pp. 472-476
    • de Belle, R.C.1
  • 23
    • 0022619404 scopus 로고
    • Development of gallbladder contractility in the guinea pig
    • Denehy CM and Ryan JR (1986) Development of gallbladder contractility in the guinea pig. Pediatr Res 20: 214-217
    • (1986) Pediatr Res , vol.20 , pp. 214-217
    • Denehy, C.M.1    Ryan, J.R.2
  • 24
    • 0023032243 scopus 로고
    • +-ATPase activity in fetal and neonatal rat liver plasma membrane vesicles
    • +-ATPase activity in fetal and neonatal rat liver plasma membrane vesicles. Am J Physiol 251: 665-673
    • (1986) Am J Physiol , vol.251 , pp. 665-673
    • Suchy, F.J.1
  • 25
    • 0036623233 scopus 로고    scopus 로고
    • Nuclear receptor regulation of hepatic function
    • Karpen SJ (2002) Nuclear receptor regulation of hepatic function. J Hepatol 36: 832-850
    • (2002) J Hepatol , vol.36 , pp. 832-850
    • Karpen, S.J.1
  • 26
    • 33745774784 scopus 로고    scopus 로고
    • Role of nuclear receptors in the adaptive response to bile acids and cholestasis: Pathogenetic and therapeutic considerations
    • Zollner G et al. (2006) Role of nuclear receptors in the adaptive response to bile acids and cholestasis: Pathogenetic and therapeutic considerations. Mol Pharm 3: 231-251
    • (2006) Mol Pharm , vol.3 , pp. 231-251
    • Zollner, G.1
  • 27
    • 4444266366 scopus 로고    scopus 로고
    • Differential expression of bile salt and organic anion transporters in developing rat liver
    • Gao B et al. (2004) Differential expression of bile salt and organic anion transporters in developing rat liver. J Hapatol 41: 201-208
    • (2004) J Hapatol , vol.41 , pp. 201-208
    • Gao, B.1
  • 28
    • 34248225386 scopus 로고    scopus 로고
    • Developmental expression of canalicular transporter genes in human liver [abstract]
    • Chen HL et al. (2004) Developmental expression of canalicular transporter genes in human liver [abstract]. J Pediatr Gastroenterol Nutr. 39 (Suppl): AS68
    • (2004) J Pediatr Gastroenterol Nutr , vol.39 , Issue.SUPPL.
    • Chen, H.L.1
  • 29
    • 23444456468 scopus 로고    scopus 로고
    • Developmental expression of canalicular transporter genes in human liver
    • Chen HL et al. (2005) Developmental expression of canalicular transporter genes in human liver. J Hepatol 43: 472-477
    • (2005) J Hepatol , vol.43 , pp. 472-477
    • Chen, H.L.1
  • 30
    • 49549145323 scopus 로고
    • Hepatic secretory obstruction with total parenteral nutrition in the infant
    • Touloukian RJ and Seashore JH (1975) Hepatic secretory obstruction with total parenteral nutrition in the infant. J Pediatr Surg 10: 353-360
    • (1975) J Pediatr Surg , vol.10 , pp. 353-360
    • Touloukian, R.J.1    Seashore, J.H.2
  • 31
    • 0021037628 scopus 로고    scopus 로고
    • Aynsley-Green A (1983) Plasma hormone concentrations during enteral and parenteral nutrition in the human newborn. J Pediatr Gastroenterol Nutr 2 (Suppi 1): S108-S112
    • Aynsley-Green A (1983) Plasma hormone concentrations during enteral and parenteral nutrition in the human newborn. J Pediatr Gastroenterol Nutr 2 (Suppi 1): S108-S112
  • 33
    • 0020698533 scopus 로고
    • Metabolic and endocrine consequences of depriving preterm infants of enteral nutrition
    • Lucas A et al. (1983) Metabolic and endocrine consequences of depriving preterm infants of enteral nutrition. Acta Paediatr Scand 72: 245-249
    • (1983) Acta Paediatr Scand , vol.72 , pp. 245-249
    • Lucas, A.1
  • 34
    • 0018546249 scopus 로고
    • Transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal bacteria
    • Fedorowski T et al. (1979) Transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal bacteria. Gastroenterology 77: 1068-1073
    • (1979) Gastroenterology , vol.77 , pp. 1068-1073
    • Fedorowski, T.1
  • 35
    • 0025136962 scopus 로고
    • Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth
    • Lichtman SN et al. (1990) Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth. Gastroenterology 98: 414-423
    • (1990) Gastroenterology , vol.98 , pp. 414-423
    • Lichtman, S.N.1
  • 36
    • 0025801063 scopus 로고
    • Biliary tract disease in rats with experimental small bowel bacterial overgrowth
    • Lichtman SN et al. (1991) Biliary tract disease in rats with experimental small bowel bacterial overgrowth. Hepatology 13 766-772
    • (1991) Hepatology , vol.13 , pp. 766-772
    • Lichtman, S.N.1
  • 37
    • 0025964069 scopus 로고
    • Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline
    • Lichtman SN et al. (1991) Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline. Gastroenterology 100: 513-519
    • (1991) Gastroenterology , vol.100 , pp. 513-519
    • Lichtman, S.N.1
  • 38
    • 0022342948 scopus 로고
    • A possible beneficial effect of metronidazole in reducing TPN-associated liver function derangements
    • Freund HR et al. (1985) A possible beneficial effect of metronidazole in reducing TPN-associated liver function derangements. J Surg Res 38: 356-363
    • (1985) J Surg Res , vol.38 , pp. 356-363
    • Freund, H.R.1
  • 39
    • 0021256120 scopus 로고
    • Cholestasis associated with parenteral nutrition develops more commonly with hematologic malignancy than with inflammatory bowel disease
    • Nanji AA and Anderson FH (1984) Cholestasis associated with parenteral nutrition develops more commonly with hematologic malignancy than with inflammatory bowel disease. JPEN J Parenter Enteral Nutr 8: 325
    • (1984) JPEN J Parenter Enteral Nutr , vol.8 , pp. 325
    • Nanji, A.A.1    Anderson, F.H.2
  • 40
    • 0020085350 scopus 로고
    • Hepatic alterations during total parenteral nutrition in patients with inflammatory bowel disease: A possible consequence of lithocholate toxicity
    • Fouin-Fortunet H et al. (1982) Hepatic alterations during total parenteral nutrition in patients with inflammatory bowel disease: A possible consequence of lithocholate toxicity. Gastroenterology 82: 932-937
    • (1982) Gastroenterology , vol.82 , pp. 932-937
    • Fouin-Fortunet, H.1
  • 41
    • 0037239933 scopus 로고    scopus 로고
    • Surgical infants on total parenteral nutrition have impaired cytokine responses to microbial challenge
    • Cruccetti A et al. (2003) Surgical infants on total parenteral nutrition have impaired cytokine responses to microbial challenge. J Pediatr Surg 38: 138-142
    • (2003) J Pediatr Surg , vol.38 , pp. 138-142
    • Cruccetti, A.1
  • 42
    • 1942420230 scopus 로고    scopus 로고
    • Endotoxin and cytokine released during parenteral nutrition
    • Zheng YJ et al. (2004) Endotoxin and cytokine released during parenteral nutrition. JPEN J Parenter Enteral Nutr 28: 163-168
    • (2004) JPEN J Parenter Enteral Nutr , vol.28 , pp. 163-168
    • Zheng, Y.J.1
  • 43
    • 0036696890 scopus 로고    scopus 로고
    • Improvement in cholestasis associated with total parenteral nutrition after treatment with an antibody against tumour necrosis factor alpha
    • Forrest EH et al. (2002) Improvement in cholestasis associated with total parenteral nutrition after treatment with an antibody against tumour necrosis factor alpha. Liver 22: 317-320
    • (2002) Liver , vol.22 , pp. 317-320
    • Forrest, E.H.1
  • 44
    • 0032882798 scopus 로고    scopus 로고
    • Inflammation-induced cholestasis
    • Trauner M et al. (1999) Inflammation-induced cholestasis. J Gastroenterol Hepatol 14: 946-959
    • (1999) J Gastroenterol Hepatol , vol.14 , pp. 946-959
    • Trauner, M.1
  • 45
    • 0031835596 scopus 로고    scopus 로고
    • Clinicopathology conferences: Inflammation-induced cholestasis
    • Crawford JM and Boyer JL (1998) Clinicopathology conferences: inflammation-induced cholestasis. Hepatology 28: 253-260
    • (1998) Hepatology , vol.28 , pp. 253-260
    • Crawford, J.M.1    Boyer, J.L.2
  • 46
    • 0032524012 scopus 로고    scopus 로고
    • Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors
    • Trauner M et al. (1998) Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors. J Clin Invest 101: 2092-2100
    • (1998) J Clin Invest , vol.101 , pp. 2092-2100
    • Trauner, M.1
  • 47
    • 18144387309 scopus 로고    scopus 로고
    • Endotoxin leads to rapid subcellular re-localization of hepatic RXRα: A novel mechanism for reduced hepatic gene expression in inflammation
    • Ghose R et al. (2004) Endotoxin leads to rapid subcellular re-localization of hepatic RXRα: A novel mechanism for reduced hepatic gene expression in inflammation. Nucl Recept 2: 4
    • (2004) Nucl Recept , vol.2 , pp. 4
    • Ghose, R.1
  • 48
    • 0037200089 scopus 로고    scopus 로고
    • Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent
    • Li D et al. (2002) Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent. J Biol Chem 277: 31416-31422
    • (2002) J Biol Chem , vol.277 , pp. 31416-31422
    • Li, D.1
  • 49
    • 0029886277 scopus 로고    scopus 로고
    • Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents
    • Green RM (1996) Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents. Gastroenterology 111: 193-198
    • (1996) Gastroenterology , vol.111 , pp. 193-198
    • Green, R.M.1
  • 50
    • 0034708264 scopus 로고    scopus 로고
    • Interleukin-1 beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation
    • Denson LA et al. (2000) Interleukin-1 beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation. J Biol Chem 275: 8835-8843
    • (2000) J Biol Chem , vol.275 , pp. 8835-8843
    • Denson, L.A.1
  • 51
    • 22044449316 scopus 로고    scopus 로고
    • Reduced bile flow associated with parenteral nutrition is independent of oxidant load and parenteral multivitamins
    • Lavoie JC et al. (2005) Reduced bile flow associated with parenteral nutrition is independent of oxidant load and parenteral multivitamins. J Pediatr Gastroenterol Nutr 4l: 108-114
    • (2005) J Pediatr Gastroenterol Nutr , vol.4 l , pp. 108-114
    • Lavoie, J.C.1
  • 52
    • 0020082098 scopus 로고
    • The development of cystathionase activity during the first year of life
    • Zlotkin SH and Anderson GH (1982) The development of cystathionase activity during the first year of life. Pediatr Res 16: 65-68
    • (1982) Pediatr Res , vol.16 , pp. 65-68
    • Zlotkin, S.H.1    Anderson, G.H.2
  • 53
    • 0021337183 scopus 로고
    • Effect of taurine supplementation on hepatic function during short-term parenteral nutrition in the premature infant
    • Cooke RJ et al. (1984) Effect of taurine supplementation on hepatic function during short-term parenteral nutrition in the premature infant. J Pediatr Gastroenterol Nutr 3: 234-238
    • (1984) J Pediatr Gastroenterol Nutr , vol.3 , pp. 234-238
    • Cooke, R.J.1
  • 54
    • 0025990550 scopus 로고
    • Effect of taurine on total parenteral nutrition-associated cholestasis
    • Guertin F et al. (1991) Effect of taurine on total parenteral nutrition-associated cholestasis. JPEN J Parenter Enteral Nutr 15: 247-251
    • (1991) JPEN J Parenter Enteral Nutr , vol.15 , pp. 247-251
    • Guertin, F.1
  • 55
    • 24944561220 scopus 로고    scopus 로고
    • Pediatric short bowel syndrome: Redefining predictors of success
    • Spencer AU et al. (2005) Pediatric short bowel syndrome: redefining predictors of success. Ann Surg 242: 403-409
    • (2005) Ann Surg , vol.242 , pp. 403-409
    • Spencer, A.U.1
  • 56
    • 0028249516 scopus 로고
    • Aluminum in the neonate related to parenteral nutrition
    • Moreno A et al. (1994) Aluminum in the neonate related to parenteral nutrition. Acta Paediatr 83: 25-29
    • (1994) Acta Paediatr , vol.83 , pp. 25-29
    • Moreno, A.1
  • 57
    • 0024314560 scopus 로고
    • Aluminum in parenteral products: Analysis, reduction, and implications for pediatric TPN
    • Rabinow, BE et al (1989) Aluminum in parenteral products: analysis, reduction, and implications for pediatric TPN. J Parenter Sci Technol 43: 132-139
    • (1989) J Parenter Sci Technol , vol.43 , pp. 132-139
    • Rabinow, B.E.1
  • 58
    • 0026595894 scopus 로고
    • Excessive chromium intake in children receiving total parenteral nutrition
    • Moukarzel AA et al. (1992) Excessive chromium intake in children receiving total parenteral nutrition. Lancet 339: 385-388
    • (1992) Lancet , vol.339 , pp. 385-388
    • Moukarzel, A.A.1
  • 59
    • 0027276366 scopus 로고
    • Chromium and parenteral nutrition in children
    • Bougle D et al. (1993) Chromium and parenteral nutrition in children. J Pediatr Gastroenterol Nutr 17: 72-74
    • (1993) J Pediatr Gastroenterol Nutr , vol.17 , pp. 72-74
    • Bougle, D.1
  • 60
    • 0031691873 scopus 로고    scopus 로고
    • Long-term outcome of brain manganese deposition in patients on home parenteral nutrition
    • Kafritsa Y et al. (1998) Long-term outcome of brain manganese deposition in patients on home parenteral nutrition. Arch Dis Child 79: 263-265
    • (1998) Arch Dis Child , vol.79 , pp. 263-265
    • Kafritsa, Y.1
  • 61
    • 0018124075 scopus 로고
    • Hepatic dysfunction during hyperalimentation
    • Sheldon GF et al. (1978) Hepatic dysfunction during hyperalimentation. Arch Surg 113: 504-508
    • (1978) Arch Surg , vol.113 , pp. 504-508
    • Sheldon, G.F.1
  • 62
    • 0018476803 scopus 로고
    • Effect of calorie overload on puppy livers during parenteral nutrition
    • Mashima Y (1979) Effect of calorie overload on puppy livers during parenteral nutrition. JPEN J Parenter Enteral Nutr 3: 139-145
    • (1979) JPEN J Parenter Enteral Nutr , vol.3 , pp. 139-145
    • Mashima, Y.1
  • 63
    • 0018848605 scopus 로고
    • Prospective controlled study of parenteral nutrition-associated cholestatic jaundice: Effect of protein intake
    • Vileisis RA et al. (1980) Prospective controlled study of parenteral nutrition-associated cholestatic jaundice: Effect of protein intake. J Pediatr 96: 893-897
    • (1980) J Pediatr , vol.96 , pp. 893-897
    • Vileisis, R.A.1
  • 64
    • 0021337419 scopus 로고
    • Inhibition of bile flow in the isolated perfused rat liver by a synthetic parenteral amino acid mixture: Associated net amino acid fluxes
    • Graham MF (1984) Inhibition of bile flow in the isolated perfused rat liver by a synthetic parenteral amino acid mixture: Associated net amino acid fluxes. Hepatology 4: 69-73
    • (1984) Hepatology , vol.4 , pp. 69-73
    • Graham, M.F.1
  • 65
    • 0021279145 scopus 로고
    • Tissue carnitine reserves of newborn infants
    • Shenai JP and Borum PR (1984) Tissue carnitine reserves of newborn infants. Pediatr Res 118: 679-682
    • (1984) Pediatr Res , vol.118 , pp. 679-682
    • Shenai, J.P.1    Borum, P.R.2
  • 66
    • 0023838125 scopus 로고
    • L-carnitine therapy in home parenteral nutrition patients with abnormal liver tests and low plasma carnitine concentrations
    • Bowyer BA et al. (1988) L-carnitine therapy in home parenteral nutrition patients with abnormal liver tests and low plasma carnitine concentrations. Gastroenterology 94: 434-438
    • (1988) Gastroenterology , vol.94 , pp. 434-438
    • Bowyer, B.A.1
  • 67
    • 0034870968 scopus 로고    scopus 로고
    • Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: Proof of a human choline requirement: A placebo-controlled trial
    • Buchman AL et al. (2001) Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: Proof of a human choline requirement: A placebo-controlled trial. JPEN J Parenter Enteral Nutr 25: 260-268
    • (2001) JPEN J Parenter Enteral Nutr , vol.25 , pp. 260-268
    • Buchman, A.L.1
  • 68
    • 0034603773 scopus 로고    scopus 로고
    • Prevalence of liver disease and contributing factors in patients receiving home parenteral nutrition for permanent intestinal failure
    • Cavicchi M et al. (2000) Prevalence of liver disease and contributing factors in patients receiving home parenteral nutrition for permanent intestinal failure. Ann Intern Med 132: 525-532
    • (2000) Ann Intern Med , vol.132 , pp. 525-532
    • Cavicchi, M.1
  • 69
    • 0033753052 scopus 로고    scopus 로고
    • Role of lipid emulsions in cholestasis associated with long-term parenteral nutrition in children
    • Colomb V et al. (2000) Role of lipid emulsions in cholestasis associated with long-term parenteral nutrition in children. JPEN J Parenter Enteral Nutr 24: 345-350
    • (2000) JPEN J Parenter Enteral Nutr , vol.24 , pp. 345-350
    • Colomb, V.1
  • 70
    • 34248180643 scopus 로고    scopus 로고
    • Soy lipid-derived stigmasterol (Stig) antagonizes bile acid (BA)-activation of the FXR dependent BA sinusoidal efflux pump genes, OSTα/β, in primary mouse hepatocytes and HepG2cells [abstract #69)
    • Carter BA et al. (2006) Soy lipid-derived stigmasterol (Stig) antagonizes bile acid (BA)-activation of the FXR dependent BA sinusoidal efflux pump genes, OSTα/β, in primary mouse hepatocytes and HepG2cells [abstract #69). J Pediatr Gastroenterol Nutr 43: E35
    • (2006) J Pediatr Gastroenterol Nutr , vol.43
    • Carter, B.A.1
  • 71
    • 34248210182 scopus 로고    scopus 로고
    • Soy-lipid derived stigmasterol suppresses FXR target genes BSEP and FGF-19, in human hepatoblastoma cells-potential role in total parenteral nutrition-associated cholestasis (TPNAC) [abstract #190]
    • Carter BA et al. (2005) Soy-lipid derived stigmasterol suppresses FXR target genes BSEP and FGF-19, in human hepatoblastoma cells-potential role in total parenteral nutrition-associated cholestasis (TPNAC) [abstract #190]. J Pediatr Gastroenterol Nutr 4l: 552
    • (2005) J Pediatr Gastroenterol Nutr , vol.4 l , pp. 552
    • Carter, B.A.1
  • 72
    • 0027141358 scopus 로고
    • Phytosterolemia in children with parenteral nutrition-associated cholestatic liver disease
    • Clayton PT et al. (1993) Phytosterolemia in children with parenteral nutrition-associated cholestatic liver disease. Gastroenterology 105: 1806-1813
    • (1993) Gastroenterology , vol.105 , pp. 1806-1813
    • Clayton, P.T.1
  • 73
    • 33746825574 scopus 로고    scopus 로고
    • Reversal of parenteral nutrition-associated liver disease in two infants with short bowel syndrome using parenteral fish oil: Implications for future management
    • Gura KM et al. (2006) Reversal of parenteral nutrition-associated liver disease in two infants with short bowel syndrome using parenteral fish oil: Implications for future management. Pediatrics 118 e197-e201
    • (2006) Pediatrics , vol.118
    • Gura, K.M.1
  • 74
    • 0345825871 scopus 로고    scopus 로고
    • Hepatic P-glycoprotein changes with total parenteral nutrition administration
    • Tezuke Y et al. (2004) Hepatic P-glycoprotein changes with total parenteral nutrition administration. JPEN J Parenter Enteral Nutr 28: 1-6
    • (2004) JPEN J Parenter Enteral Nutr , vol.28 , pp. 1-6
    • Tezuke, Y.1
  • 75
    • 3142620957 scopus 로고    scopus 로고
    • Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN)
    • Tazuke Y (2004) Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN). Pediatr Surg Int 20: 224-228
    • (2004) Pediatr Surg Int , vol.20 , pp. 224-228
    • Tazuke, Y.1
  • 76
    • 24344474377 scopus 로고    scopus 로고
    • The route of lipid administration affects parenteral nutrition-induced hepatic steatosis in a mouse model
    • Javid PJ et al. (2005) The route of lipid administration affects parenteral nutrition-induced hepatic steatosis in a mouse model. J Pediatr Surg 40: 1446-1453
    • (2005) J Pediatr Surg , vol.40 , pp. 1446-1453
    • Javid, P.J.1
  • 77
    • 33744920572 scopus 로고    scopus 로고
    • Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis
    • Beuers U (2006) Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis. Nat Clin Pract Gastroenterol Hepatol 3: 318-328
    • (2006) Nat Clin Pract Gastroenterol Hepatol , vol.3 , pp. 318-328
    • Beuers, U.1
  • 78
    • 0036016511 scopus 로고    scopus 로고
    • The biochemical and histopathological effects of ursodeoxycholic acid and metronidazole on total parenteral nutrition-associated hepatic dysfunction: An experimental study
    • Gunsar C et al. (2002) The biochemical and histopathological effects of ursodeoxycholic acid and metronidazole on total parenteral nutrition-associated hepatic dysfunction: An experimental study. Hepatogastroenterology 49: 497-500
    • (2002) Hepatogastroenterology , vol.49 , pp. 497-500
    • Gunsar, C.1
  • 79
    • 33745679125 scopus 로고    scopus 로고
    • Early treatment with ursodeoxycholic acid for cholestasis in children on parenteral nutrition because of primary intestinal failure
    • De Marco G et al. (2006) Early treatment with ursodeoxycholic acid for cholestasis in children on parenteral nutrition because of primary intestinal failure. Aliment Pharmacol Ther 24, 387-394
    • (2006) Aliment Pharmacol Ther , vol.24 , pp. 387-394
    • De Marco, G.1
  • 80
    • 0028268726 scopus 로고
    • Is ursodeoxycholic acid an effective therapy for total parenteral nutrition-related liver disease?
    • Beau P et al. (1994) Is ursodeoxycholic acid an effective therapy for total parenteral nutrition-related liver disease? J Hepatol 20: 240-244
    • (1994) J Hepatol , vol.20 , pp. 240-244
    • Beau, P.1
  • 81
    • 0025860954 scopus 로고
    • Ursodeoxycholic acid for the treatment of home parenteral nutrition-associated cholestasis: A case report
    • Lindor KD and Burnes J (1991) Ursodeoxycholic acid for the treatment of home parenteral nutrition-associated cholestasis: A case report. Gastroenterology 101: 250-253
    • (1991) Gastroenterology , vol.101 , pp. 250-253
    • Lindor, K.D.1    Burnes, J.2
  • 82
    • 0029788999 scopus 로고    scopus 로고
    • Ursodeoxycholic acid for treatment of cholestasis in children on long-term total parenteral nutrition: A pilot study
    • Spagnuolo MI et al. (1996) Ursodeoxycholic acid for treatment of cholestasis in children on long-term total parenteral nutrition: A pilot study. Gastroenterology 111: 716-719
    • (1996) Gastroenterology , vol.111 , pp. 716-719
    • Spagnuolo, M.I.1
  • 83
    • 12444323678 scopus 로고    scopus 로고
    • Failure of cholecystokinin-octapeptide to prevent TPN-associated gallstone disease
    • Tsai S et al. (2005) Failure of cholecystokinin-octapeptide to prevent TPN-associated gallstone disease. J Pediatr Surg 40: 263-267
    • (2005) J Pediatr Surg , vol.40 , pp. 263-267
    • Tsai, S.1
  • 84
    • 25144495661 scopus 로고    scopus 로고
    • Use of cholecystokinin-octapeptide for the prevention of parenteral nutrition-associated cholestasis
    • Teitelbaum DH et al. (2005) Use of cholecystokinin-octapeptide for the prevention of parenteral nutrition-associated cholestasis. Pediatrics 115: 1332-1340
    • (2005) Pediatrics , vol.115 , pp. 1332-1340
    • Teitelbaum, D.H.1
  • 85
    • 0036695454 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid (TUDCA) in the prevention of total parenteral nutrition-associated liver disease
    • Heubi JE et al. (2002) Tauroursodeoxycholic acid (TUDCA) in the prevention of total parenteral nutrition-associated liver disease. J Pediatr 141: 237-242
    • (2002) J Pediatr , vol.141 , pp. 237-242
    • Heubi, J.E.1
  • 86
    • 34248169266 scopus 로고    scopus 로고
    • Isolated orthotopic liver transplantation for parenteral nutrition-associated liver injury
    • Barshes NR (2006) Isolated orthotopic liver transplantation for parenteral nutrition-associated liver injury. JPEN J Parenter Enteral Nutr 30: 526-629
    • (2006) JPEN J Parenter Enteral Nutr , vol.30 , pp. 526-629
    • Barshes, N.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.