Kinetic mechanism of enterococcal aminoglycoside phosphotransferase 2″-Ib

Biochemistry

Volumn 46, Issue 18, 2007, Pages 5570-5578

  Toth, Marta ^a   Zajicek, Jaroslav ^a   Kim, Choonkeun ^a   Chow, Joseph W ^b   Smith, Clyde ^c   Mobashery, Shahriar ^a   Vakulenko, Sergei ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITION PATTERNS; SEQUENTIAL MECHANISM; SUBSTRATE BINDING;

BACTERIA; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORYLATION; REACTION KINETICS; SUBSTITUTION REACTIONS; VISCOSITY;

ENZYMES;

AMINOGLYCOSIDE 2'' 1B PHOSPHOTRANSFERASE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; KANAMYCIN A; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; BACTERIUM ISOLATE; CONTROLLED STUDY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; KINETICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; VISCOSITY;

BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; ENTEROCOCCUS FAECIUM; KANAMYCIN; KINETICS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PILOT PROJECTS; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

EID: 34248147112     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi6024512     Document Type: Article

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