Bcl-2 over-expression fails to prevent age-related loss of calretinin positive neurons in the mouse dentate gyrus

Molecular Neurodegeneration

Volumn 1, Issue 1, 2006, Pages

  Han, Mingbo ^a   Schottler, Frank ^a   Lei, Debin ^a   Dong, Elizabeth Y ^a   Bryan, Alexander ^a   Bao, Jianxin ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUS; MUS MUSCULUS;

EID: 34248141099     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-1-9     Document Type: Article

References (53)

1. Gallagher M, Rapp PR: The use of animal models to study the effects of aging on cognition. Annul Rev Psychol 2003, 48:339-370.
2. Finch CE: Neurons, glia, and plasticity in normal brain aging. Neurobiol Aging Suppl 2003, 1:S123-127.
3. Rosenzweig ES, Barnes CA: Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition. Prog Neurobiol 2003, 69:143-179.
4. Hof PR, Morrison JH: The aging brain: morphomolecular senescence of cortical circuits. Trends Neurosci 2004, 27:607-613.
5. Lynch MA: Analysis of the mechanisms underlying the age-related impairment in long-term potentiation in the rat. Rev Neurosci 1998, 9:169-201.
6. Barnes CA: Long-term potentiation and the ageing brain. Philos Trans R Soc Lond B Biol Sci 2003, 358:765-772.
7. Pang PT, Lu B: Regulation of late-phase LTP and long-term memory in normal and aging hippocampus: role of secreted proteins tPA and BDNF. Ageing Res Rev 2004, 3:407-30.
8. Jack CR Jr, Petersen RC, Xu YC, Waring SC, O'Brien PC, Tangalos EG, Smith GE, Ivnik RJ, Kokmen E: Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology 1998, 49:786-794.
9. Pruessner JC, Collins DL, Pruessner M, Evans AC: Age and gender predict volume decline in the anterior and posterior hippocampus in early adulthood. J Neurosci 2001, 21:194-200.
10. Driscoll I, Hamilton DA, Petropoulos H, Yeo RA, Brooks WM, Baumgartner RN, Sutherland RJ: The aging hippocampus: cognitive, biochemical and structural findings. Cereb Cortex 2003, 13:1344-1351.
11. Coleman PD, Flood DG: Neuron numbers and dendritic extent in normal aging and Alzheimer's disease. Neurobiol Aging 1987, 8:521-545.
12. Rapp PR, Gallagher M: Preserved neuron number in the hippocampus of aged rats with spatial learning deficits. Proc Natl Acad Sci USA 1996, 93:9926-99230.
13. Rasmussen T, Schliemann T, Sorensen JC, Zimmer J, West MJ: Memory impaired aged rats: no loss of principal hippocampal and subicular neurons. Neurobiol Aging 1996, 17:143-147.
14. Calhoun ME, Kurth D, Phinney AL, Long JM, Hengemihle J, Mouton PR, Ingram DK, Jucker M: Hippocampal neuron and synapto-physin-positive bouton number in aging C57BL/6 mice. Neurobiol Aging 1998, 19:599-606.
15. West MJ, Gundersen HJ: Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 1990, 296:1-22.
16. West MJ: Regionally specific loss of neurons in the aging human hippocampus. Neurobiol Aging 1993, 14:287-293.
17. Gallagher M, Landfield PW, McEwen B, Meaney MJ, Rapp PR, Sapolsky R, West MJ: Hippocampal neurodegeneration in aging. Science 1996, 274:484-485.
18. von Bohlen und Halbach O, Unsicker K: Morphological alterations in the amygdala and hippocampus of mice during ageing. Eur J Neurosci 2002, 16:2434-2440.
19. Villa A, Podini P, Panzeri MC, Racchetti G, Meldolesi J: Cytosolic Ca2+ binding proteins during rat brain ageing: loss of calbindin and calretinin in the hippocampus, with no change in the cerebellum. Eur J Neurosci 1994, 6:1491-1499.
20. Shetty AK, Turner DA: Hippocampal interneurons expressing glutamic acid decarboxylase and calcium-binding proteins decrease with aging in Fischer 344 rats. J Comp Neurol 1998, 394:252-269.
21. Bu J, Sathyendra V, Nagykery N, Geula C: Age-related changes in calbindin-D28k, calretinin, and parvalbumin-immunoreactive neurons in the human cerebral cortex. Exp Neurol 2003, 182:220-231.
22. Cadacio CL, Milner TA, Gallagher M, Pierce JP: Hilar neuropeptide Y interneuron loss in the aged rat hippocampal formation. Exp Neurol 2003, 183:147-158.
23. Stanley DP, Shetty AK: Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration. J Neurochem 2004, 89:204-216.
24. Yuan J, Lipinski M, Degterev A: Diversity in the mechanisms of neuronal cell death. Neuron 2003, 40:401-413.
25. Bakhshi A, Jensen JP, Goldman P, Wright JJ, McBride OW, Epstein AL, Korsmeyer SJ: Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18. Cell 1985, 41:899-906.
26. Cleary ML, Sklar J: Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci USA 1985, 82:7439-7443.
27. Tsujimoto Y, Gorham J, Cossman J, Jaffe E, Croce CM: The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 1985, 229:1390-1393.
28. Merry DE, Veis DJ, Mickey WF, Korsmeyer SJ: bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development 1994, 120:301-311.
29. Farlie PG, Dringen R, Rees SM, Kannourakis G, Bernard O: bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc Natl Acad Sci USA 1995, 92:4397-4401.
30. Chen J, Flannery JG, LaVail MM, Steinberg RH, Xu J, Simon Ml: bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations. Proc Natl Acad Sci USA 1996, 93:7042-7047.
31. Putcha GV, Johnson EM Jr: Men are but worms: neuronal cell death in C elegans and vertebrates. Cell Death Differ 2004, 11:38-48.
32. Houseweart MK, Cleveland DW: Bcl-2 overexpression does not protect neurons from mutant neurofilament-mediated motor neuron degeneration, J Neurosci 1999, 19:6446-6456.
33. Zanjani H, Lemaigre-Dubreuil Y, Tillakaratne NJ, Blokhin A, McMahon RP, Tobin AJ, Vogel MW, Mariani J: Cerebellar Purkinje cell loss in aging Hu-Bcl-2 transgenic mice. J Comp Neurol 2004, 475:481-492.
34. Kaufmann JA, Bickford PC, Taglialatela G: Oxidative-stress-dependent up-regulation of Bcl-2 expression in the central nervous system of aged Fisher-344 rats. J Neurochem 2001, 76:1099-1108.
35. Fujise N, Kosaka T: Mossy cells in the mouse dentate gyrus: identification in the dorsal hilus and their distribution along the dorsoventral axis. Brain Res 1999, 816:500-511.
36. Jinno S, Kosaka T: Patterns of expression of calcium binding proteins and neuronal nitric oxide synthase in different populations of hippocampal GABAergic neurons in mice. J Comp Neurol 2002, 449:1-25.
37. Brandt MD, Jessberger S, Steiner B, Kronenberg G, Reuter K, Bick-Sander A, von der Behrens W, Kempermann G: Transient calretinin expression defines early postmitotic step of neuronal differentiation in adult hippocampal neurogenesis of mice. Mol Cell Neurosci 2003, 24:603-613.
38. Matyas F, Freund TF, Gulyas Al: Immunocytochemically defined interneuron populations in the hippocampus of mouse strains used in transgenic technology. Hippocampus 2004, 14:460-481.
39. Liu Y, Fujise N, Kosaka T: Distribution of calretinin immunore-activity in the mouse dentate gyrus. I. General description. Exp Brain Res 1996, 108:389-403.
40. Blasco-lbanez JM, Freund TF: Distribution, ultrastructure, and connectivity of calretinin-immunoreactive mossy cells of the mouse dentate gyrus. Hippocampus 1997, 7:307-20.
41. Fujise N, Liu Y, Hori N, Kosaka T: Distribution of calretinin immunoreactivity in the mouse dentate gyrus: II. Mossy cells, with special reference to their dorsoventral difference in calretinin immunoreactivity. Neuroscience 1998, 82:181-200.
42. Martinou JC, Dubois-Dauphin M, Staple JK, Rodriguez I, Frankowski H, Missotten M, Albertini P, Talabot D, Catsicas S, Pietra C, Huarte J: Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 1994, 13:1017-1030.
43. Rondi-Reig L, Mariani J: To die or not to die, does it change the function? Behavior of transgenic mice reveals a role for developmental cell death. Brain Res Bull 2002, 57:85-91.
44. Brown JP, Couillard-Despres S, Cooper-Kuhn CM, Winkler J, Aigner L, Kuhn HG: Transient expression of doublecortin during adult neurogenesis. J Comp Neural 2003, 467:1-10.
45. Kempermann G, Jessberger S, Steiner B, Kronenberg G: Milestones of neuronal development in the adult hippocampus. Trends Neurosci 2004, 27:447-452.
46. Kuhn HG, Dickinson-Anson H, Gage FH: Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 1996, 16:2027-2033.
47. Kuhn HG, Biebl M, Wilhelm D, Li M, Friedlander RM, Winkler J: Increased generation of granule cells in adult Bcl-2-overexpressing mice: a role for cell death during continued hippocampal neurogenesis. Eur J Neurosci 2005, 22:1907-1915.
48. Buckmaster PS, Schwartzkroin PA: Hippocampal mossy cell function: a speculative view. Hippocampus 1994, 4:393-402.
49. Nicoll RA, Schmilz D: Synaptic plasticity at hippocampal mossy fibre synapses. Nat Rev Neurosci 2005, 6:863-876.
50. Rondi-Reig L, Lemaigre-Dubreuil Y, Montecot C, Muller D, Martinou JC, Caston J, Mariani J: Transgenic mice with neuronal overexpression of bcl-2 gene present navigation disabilities in a water task. Neuroscience 2001, 104:207-215.
51. Schurmans S, Schiffmann SN, Gurden H, Lemaire M, Lipp HP, Schwam V, Pochet R, Imperato A, Bohme GA, Parmentier M: Impaired long-term potentiation induction in dentate gyrus of calretinin-deficient mice. Proc Natl Acad Sci USA 1997, 94:10415-10420.
52. Gurden H, Schiffmann SN, Lemaire M, Bohme GA, Parmentier M, Schurmans S: Calretinin expression as a critical component in the control of dentate gyrus long-term potentiation induction in mice. Eur J Neurosci 1998, 10:3029-3033.
53. West MJ: Design-based stereological methods for counting neurons. Prog Brain Res 2002, 135:43-51.