Differential ras activation between caveolae/raft and non-raft microdomains

Cell Structure and Function

Volumn 32, Issue 1, 2007, Pages 9-15

  Fukano, Takashi ^a   Sawano, Asako ^a   Ohba, Yusuke ^b   Matsuda, Michiyuki ^b   Miyawaki, Atsushi ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

FRET; Fringe projection; Ras

Indexed keywords

GREEN FLUORESCENT PROTEIN; GROWTH FACTOR; HYBRID PROTEIN; MUTANT PROTEIN; RAS PROTEIN; YELLOW FLUORESCENT PROTEIN; EPIDERMAL GROWTH FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CAVEOLA; CELL MEMBRANE; DEVICE; ENDOSOME; FLUORESCENCE MICROSCOPE; FLUORESCENCE RESONANCE ENERGY TRANSFER; LIPID RAFT; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; COMPARATIVE STUDY; DRUG EFFECT; METABOLISM;

ANIMALS; CAVEOLAE; CERCOPITHECUS AETHIOPS; COS CELLS; EPIDERMAL GROWTH FACTOR; MEMBRANE MICRODOMAINS; RAS PROTEINS;

EID: 34247868273     PISSN: 03867196     EISSN: 13473700     Source Type: Journal    
DOI: 10.1247/csf.06019     Document Type: Article

References (20)

1. Apolloni, A., Prior, I.A., Lindsay, M., Parton, R.G., and Hancock, J.F. 2000. H-Ras but not K-Ras traffics to the plasma membrane through the exocytic pathway. Mol. Cell. Biol., 20: 2475-2487.
2. Bar-sagi, D. 2001. A Ras by any other name. Mol. Cell. Biol., 21: 1441-1443.
3. Chiu, V.K., Bivona, T., Hach, A., Sajous. J.B., Silletti, J., Wiener, H., Johnson, R.L.II., Cox, A.D., and Philips, M.R. 2002. Ras signalling on the endoplasmic reticulum and the Golgi. Nat. Cell. Biol., 4: 343-350.
4. Fukano, T. and Miyawaki, A. 2003. Whole-field fluorescence microscope with digital micromirror device: imaging of biological samples. Appl. Opt., 42: 4119-4124.
5. Furuchi, T. and Anderson, R.G.W. 1998. Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK). J. Biol. Chem., 273: 21099-21104.
6. Hancock, J.F. 2003. Ras proteins: different signals from different locations. Nat. Rev. Mol. Cell Biol., 4: 373-384.
7. Kreis, T. 1996. Holographic interferometry: Principles and methods. Akademie Verlag, Berlin.
8. Miyawaki, A. 2003. Visualization of the spatial and temporal dynamics of intracellular signalling. Dev. Cell., 4: 295-305.
9. Mochizuki, N., Yamashita, S., Kurokawa, K., Ohba, Y., Nagai, T., Miyawaki, A., and Matsuda, M. 2001. Spatio-temporal images of growth-factor-induced activation of Ras and Rap1. Nature, 411: 1065-1068.
10. Neil, M.A.A., Juskaitis, R., and Wilson, T. 1997. Method of obtaining optical sectioning by using structured light in a conventional microscope. Opt. Lett., 22: 1905-1907.
11. Prior, I.A. and Hancock, J.F. 2001. Compartmentalization of Ras proteins. J. Cell Sci., 114: 1603-1608.
12. Prior, I.A., Harding, A., Yan. J., Sluimer, J., Parton. R.G., and Hancock, J.F. 2001. GTP-dependent segregation of H-Ras from lipid rafts is required for biological activity. Nat. Cell. Biol., 3: 368-375.
13. Prior, I.A., Muncke, C., Parton, R.G., and Hancock, J.F. 2003. Direct visualization of Ras proteins in spatially distinct cell surface microdomains. J. Cell. Biol., 160: 165-170.
14. Rocks, O., Peyker, A., Kahms, M., Verveer, P.J., Koerner, C., Lumbierres. M., Kuhlmann, J., Waldmann, H., Wittinghofer, A., and Bastianens, P.I. 2005. An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science, 307: 1746-1752.
15. Rodriguez-Viciana, P. and McCormick, F. 2006. Ras ubiquitination: Coupling spatial sorting and signal transmission. Cancer Cell, 9: 243-244.
16. Roy, S., Luetterforst, R., Harding, A., Apolloni, A., Etheridge, M., Stang, E., Rolls, B., Hancock, J.F., and Parton, R.G. 1999. Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains. Nat. Cell. Biol., 1: 98-105.
17. Shields, J.M., Pruitt, K., McFall, A., Shaub, A., and Der, C.J. 2000. Understanding Ras: 'it ain't over 'til it's over'. Trends in Cell Biol., 10: 147-154.
18. Sternberg, P.W. and Schmid, S.L. 1999. Caveolin, cholesterol and Ras signaling. Nat. Cell. Biol., 1: E35-E37.
19. White, M.A. and Anderson, R.G.W. 2001. Which Ras rides raft? Nat. Cell Biol., 3: E172.
20. Yan, J., Roy, S., Apolloni, A., Lane, A., and Hancock, J.F. 1998. Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase. J. Biol. Chem., 273: 24052-24056.