A ras by any other name

Molecular and Cellular Biology

Volumn 21, Issue 5, 2001, Pages 1441-1443

  Bar Sagi, D ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE TARGETING; MOLECULAR GENETICS; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SHORT SURVEY;

ANIMALS; CELL MEMBRANE; CONSERVED SEQUENCE; HUMANS; MODELS, BIOLOGICAL; MULTIGENE FAMILY; RAS PROTEINS; TUMOR CELLS, CULTURED;

EID: 0035131187     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.5.1441-1443.2001     Document Type: Short Survey

References (27)

1. H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway
2. Ras genes
3. Ras oncogenes in human cancer: A review
4. p21ras is modified by a farnesyl isoprenoid
5. Expression of p21ras in normal and malignant human tissues: Lack of association with proliferation and malignancy
6. Endomembrane trafficking of ras: The CAAX motif targets proteins to the ER and Golgi
7. Protein isoprenylation and methylation at carboxyl-terminal cysteine residues
8. Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development
9. Expression of ras proto-oncogene proteins in normal human tissues
10. Posttranslational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis
11. Ha-ras and N-ras regulate MAPK activity by distinct mechanisms in vivo
12. All ras proteins are polyisoprenylated but only some are palmitoylated
13. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
14. K-ras is an essential gene in the mouse with partial functional overlap with N-ras
15. Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo
16. K-ras is essential for the development of the mouse embryo
17. Differential expression of the ras gene family in mice
18. Function and regulation of ras
19. Transcription of c-onc genes c-rasKi and c-fms during mouse development
20. Electrostatic interaction of myristoylated proteins with membranes: Simple physics, complicated biology
21. Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
22. Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains
23. Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers
24. The murine N-ras gene is not essential for growth and development
25. Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility
26. Harvey murine sarcoma virus p21 ras protein: Biological and biochemical significance of the cysteine nearest the carboxy terminus
27. Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase