Arg82p is a bifunctional protein whose inositol polyphosphate kinase activity is essential for nitrogen and PHO gene expression but not for Mcm1p chaperoning in yeast

Molecular Microbiology

Volumn 49, Issue 2, 2003, Pages 457-468

  El Alami, Mohamed ^a   Messenguy, Francine ^a   Scherens, Bart ^a   Dubois, Evelyne ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CHAPERONE; FUNGAL ENZYME; FUNGAL PROTEIN; INOSITOL POLYPHOSPHATE KINASE; NITROGEN; PHOSPHATE; POLYASPARTIC ACID; PROTEIN MADS BOX; PROTEIN MCM1P; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CATALYSIS; DNA MICROARRAY; ENZYME ACTIVITY; ENZYME SYNTHESIS; FUNGAL GENE; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; STRESS;

GENE EXPRESSION REGULATION, FUNGAL; GENES, REPORTER; INOSITOL PHOSPHATES; NITROGEN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0038162581     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2003.03562.x     Document Type: Article

References (38)

1. Althoefer, H., Schleiffer, A., Wassmann, K., Nordheim, A., and Ammerer, G. (1995) Mcm1 is required to coordinate G2-specific transcription in Saccharomyces cerevisiae. Mol Cell Biol 15: 5917-5928.
2. Amar, N., Messenguy, F., El Bakkoury, M., and Dubois, E. (2000) ArgRII, a component of the ArgR-Mcm1 complex invorved in the control of arginine metabolism in Saccharomyces cerevisiae, is the sensor of arginine. Mol Cell Biol 20: 2087-2097.
3. Banuett, F. (1998) Signalling in the yeasts: an informational cascade with links to the filamentous fungi. Microbiol Mol Biol Rev 62: 249-274.
4. Brachmann, C.B., Davies, A., Cost, G.J., Caputo, E., Li, J., Hieter, P., and Boeke, J.D. (1998) Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14: 115-132.
5. Carroll, A.S., and O'Shea, E.K. (2002) Pho85 and signaling environmental conditions. Trends Biochem Sci 27: 87-93.
6. Dubois, E., and Messenguy, F. (1994) Pleiotropic function of ArgRIIIp (Arg82p), one of the regulators of arginine metabolism in Saccharomyces cerevisiae. Role in expression of cell-type-specific genes. Mol Gen Genet 243: 315-324.
7. Dubois, E., Dewaste, V., Erneux, C., and Messenguy, F. (2000) Inositol polyphosphate kinase activity of Arg82/ArgRIII is not required for the regulation of the arginine metabolism in yeast. FEBS Lett 486: 300-304.
8. Dubois, E., Scherens, B., Vierendeels, F., Ho, M.M., Messenguy, F., and Shears, S.B. (2002) In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis. J Biol Chem 277: 23755-23763.
9. Durfee, T., Becherer, K., Chen, P.L., Yeh, S.H., Yang, Y., Kilburn, A.E., et al. (1993) The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev 7: 555-569.
10. El Bakkoury, M., Dubois, E., and Messenguy, F. (2000) Recruitment of the yeast MADS-box proteins, ArgRI and Mcm1 by the pleiotropic factor ArgRIII is required for their stability. Mol Microbiol 35: 15-31.
11. Elble, R., and Tye, B.K. (1992) Chromosome loss, hyper-recombination, and cell cycle arrest in a yeast mcm1 mutant. Mol Biol Cell 3: 971-980.
12. Foury, F., and Talibi, D. (2001) Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. J Biol Chem 276: 7762-7768.
13. Guldener, U., Heck, S., Fiedler, T., Beinhauwer, J., and Hegemann, J.H. (1996) A new efficient gene disruption cassette for repeated use in budding yeast. Nucleic Acids Res 24: 2519-2524.
14. Jarvis, E.E., Clark, K.L., and Sprague, G.F., Jr (1989) The yeast transcription activator PRTF, a homolog of the mammalian serum response factor, is encoded by the MCM1 gene. Genes Dev 3: 936-945.
15. Kaffman, A., and O'Shea, E.K. (1999) Regulation of nuclear localization: a key to a door. Ann Rev Cell Dev Biol 15: 291-339.
16. Kaffman, A., Herskowitz, I., Tjian, R., and O'Shea, E.K. (1994) Phosphorylation of transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85. Science 263: 1153-1156.
17. Komeili, A., and O'Shea, E.K. (1999) Roles of phosphorylation sites in regulating activity of the transcription factor Pho4. Science 284: 977-980.
18. Kuo, M.H., Nadeau, E.T., and Grayhack, E.J. (1997) Multiple phosphorylated forms of the Saccharomyces cerevisiae Mcm1 protein include an isoform induced in response to high salt concentrations. Mol Cell Biol 17: 819-832.
19. Louvet, O., Doignon, F., and Crouzet, M. (1997) Stable DNA-binding yeast vector allowing high-bait expression for use in the two-hybrid system. Biotechniques 23: 816-818, 820.
20. Luo, H.R., Saiardi, A., Nagata, E., Ye, K., Yu, H., Jung, T.S., et al. (2001) GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase. Neuron 31: 439-451.
21. Magasanik, B., and Kaiser, C.A. (2002) Nitrogen regulation in Saccharomyces cerevisiae. Gene 290: 1-18.
22. McInerny, C.J., Partridge, J.F., Mikesell, G.E., Creemer, D.P., and Breeden, L.L. (1997) A novel Mcm1-dependent element in the SW14, CLN3, CDC6, and CDC47 promoters activates M/G1-specific transcription. Genes Dev 11: 1277-1288.
23. Messenguy, F. (1976) Regulation of arginine biosynthesis in Saccharomyces cerevisiae: isolation of a cis-dominant, constitutive mutant for ornithine carbamoyltransferase synthesis. J Bacteriol 128: 49-55.
24. Messenguy, F., and Dubois, E. (1993) Genetic evidence for a role for MCM1 in the regulation of arginine metabolism in Saccharomyces cerevisiae. Mol Cell Biol 13: 2586-2592.
25. Miller, J. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
26. Oehlen, L.J., McKinney, J.D., and Cross, F.R. (1996) Ste12 and Mcm1 regulate cell cycle-dependent transcription of FAR1. Mol Cell Biol 16: 2830-2837.
27. Ongusaha, P.P., Hughes, P.J., Davey, J., and Michell, R.H. (1998) Inositol hexakisphosphate in Schizosaccharomyces pombe: synthesis from Ins (1,4,5) P3 and osmotic regulation. Biochem J 335: 671-679.
28. Oshima, Y. (1997) The phosphatase system in Saccharomyces cerevisiae. Genes Genet Syst 72: 323-334.
29. Passmore, S., Maine, G.T., Elble, R., Christ, C., and Tye, B.K. (1988) Saccharomyces cerevisiae protein involved in plasmid maintenance is necessary for mating of MAT alpha cells. J Mol Biol 204: 593-606.
30. Qiu, H.F., Dubois, E., Broen, P., and Messenguy, F. (1990) Functional analysis of ARGRI and ARGRIII regulatory proteins involved in the regulation of arginine metabolism in Saccharomyces cerevisiae. Mol Gen Genet 222: 192-200.
31. Saiardi, A., Erdjument-Bromage, H., Snowman, A.M., Tempst, P., and Snyder, S.H. (1999) Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases. Curr Biol 9: 1323-1326.
32. Saiardi, A., Caffrey, J.J., Snyder, S.H., and Shears, S.B. (2000) The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis. J Biol Chem 275: 24686-24692.
33. Schmitt, M.E., Brown, T.A., and Trumpower, B.L. (1990) A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res 18: 3091-3092.
34. Schneider, K.R., Smith, R.L., and O'Shea, E.K. (1994) Phosphate-regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81. Science 266: 122-126.
35. Steger, D.J., Haswell, E.S., Miller, A.L., Wente, S.R., and O'Shea, E.K. (2003) Regulation of chromatin remodeling by inositol polyphosphates. Science 299: 114-116.
36. Toh-E, A., Ueda, Y., Kakimoto, S.I., and Oshima, Y. (1973) Isolation and characterization of acid phosphatase mutants in Saccharomyces cerevisiae. J Bacteriol 113: 727-738.
37. Wach, A. (1996) PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in Saccharomyces cerevisiae. Yeast 12: 259-265.
38. York, J.D., Odom, A.R., Murphy, R., Ives, E.B., and Wente, S.R. (1999) A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export, Science 285: 96-100.