Association testing of common variants in the insulin receptor substrate-1 gene (IRS1) with type 2 diabetes

Diabetologia

Volumn 50, Issue 6, 2007, Pages 1209-1217

  Florez, J C ^a,b,c   Sjogren M ^d   Agapakis, C M ^a,c,k   Burtt, N P ^c   Almgren, P ^d   Lindblad, U ^d   Berglund, G ^d   Tuomi, T ^e,f,g   Gaudet, D ^h   Daly, M J ^a,c   Ardlie, K G ^c,i   Hirschhorn, J N ^b,c,j   Altshuler, D ^a,b,c   Groop, L ^d,e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d LUND UNIVERSITY HOSPITAL   (Sweden)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^f UNIVERSITY OF HELSINKI   (Finland)

^g FOLKHÄLSAN RESEARCH CENTER   (Finland)

^h UNIVERSITÉ DE MONTRÉAL   (Canada)

ⁱ Genomics Collaborative Inc   (United States)

^j BOSTON CHILDREN S HOSPITAL   (United States)

^k HARVARD UNIVERSITY   (United States)

more..

Author keywords

Common variants; Genetic association; Insulin resistance; IRS1; Linkage disequilibrium; Single nucleotide polymorphism; SNP; Type 2 diabetes

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 2;

ADULT; AGED; ALLELE; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NORTH AMERICA; PRIORITY JOURNAL; QUANTITATIVE TRAIT; RECEPTOR GENE;

AGED; BODY MASS INDEX; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; MALE; MIDDLE AGED; PHOSPHOPROTEINS; POLAND; POLYMORPHISM, SINGLE NUCLEOTIDE; SIGNAL TRANSDUCTION; SWEDEN; UNITED STATES; VARIATION (GENETICS);

EID: 34247844402     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-007-0657-5     Document Type: Article

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