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Volumn 52, Issue 5, 2006, Pages 4-10

The correlation of homocysteine-thiolactonase activity of the paraoxonase (PON1) protein with coronary heart disease status

Author keywords

Age; Atherosclerosis; Genetic polymorphism; HDL; Homocysteine thiolactonase; LDL; Paraoxonase; Statins; Total cholesterol

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; ARYLDIALKYLPHOSPHATASE 1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOMOCYSTEINE THIOLACTONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 34247640295     PISSN: 01455680     EISSN: 1165158X     Source Type: Journal    
DOI: 10.1170/T727     Document Type: Article
Times cited : (51)

References (40)
  • 2
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis, A.J., Atherosclerosis. Nature 2000, 407: 233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 3
    • 4043096346 scopus 로고    scopus 로고
    • Paraoxonase 1 activity, concentration and genotype in cardiovascular disease
    • Mackness, M., Durrington, P. and Mackness, B., Paraoxonase 1 activity, concentration and genotype in cardiovascular disease. Curr. Opin. Lipidol. 2004, 15: 399-404.
    • (2004) Curr. Opin. Lipidol , vol.15 , pp. 399-404
    • Mackness, M.1    Durrington, P.2    Mackness, B.3
  • 10
    • 1542331537 scopus 로고    scopus 로고
    • Keavney, B.D., Watkins, H., Collins, R. and Danesh, J., Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: Meta-analysis of 43 studies
    • Wheeler, J.W., Keavney, B.D., Watkins, H., Collins, R. and Danesh, J., Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies. Lancet 2004, 363: 689-695.
    • (2004) Lancet , vol.363 , pp. 689-695
    • Wheeler, J.W.1
  • 11
    • 0037423286 scopus 로고    scopus 로고
    • Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles
    • Marthe, G.K., Zimmerman, G.A. and McIntyre, T.M., Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles. J. Biol. Chem. 2003, 278: 3937-3947.
    • (2003) J. Biol. Chem , vol.278 , pp. 3937-3947
    • Marthe, G.K.1    Zimmerman, G.A.2    McIntyre, T.M.3
  • 12
    • 10044261174 scopus 로고    scopus 로고
    • Purified human serum PON1 does not protect LDL against oxidation in the in vitro assays initiated with copper or AAPH
    • Teiber, J.F., Dragonov, D. and Maguire, G.F., Purified human serum PON1 does not protect LDL against oxidation in the in vitro assays initiated with copper or AAPH. J. Lipid Res. 2004, 45: 2260-2268.
    • (2004) J. Lipid Res , vol.45 , pp. 2260-2268
    • Teiber, J.F.1    Dragonov, D.2    Maguire, G.F.3
  • 13
    • 10644283921 scopus 로고    scopus 로고
    • Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite
    • Connelly, P.W., Draganov, D. and Maguire, G.F., Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite. Free Radic. Biol. Med. 2005, 38: 164-174.
    • (2005) Free Radic. Biol. Med , vol.38 , pp. 164-174
    • Connelly, P.W.1    Draganov, D.2    Maguire, G.F.3
  • 14
    • 1542373560 scopus 로고    scopus 로고
    • Molecular basis of homocysteine toxicity in humans
    • Jakubowski, H., Molecular basis of homocysteine toxicity in humans. Cell. Mol. Life Sci. 2004, 61: 470-487.
    • (2004) Cell. Mol. Life Sci , vol.61 , pp. 470-487
    • Jakubowski, H.1
  • 15
    • 0034635449 scopus 로고    scopus 로고
    • Calcium-dependent human serum homocysteine thiolactone hydrolase: A protective mechanism against protein N-homocysteinylation
    • Jakubowski, H., Calcium-dependent human serum homocysteine thiolactone hydrolase: A protective mechanism against protein N-homocysteinylation. J. Biol. Chem. 2000, 275: 3957-3962.
    • (2000) J. Biol. Chem , vol.275 , pp. 3957-3962
    • Jakubowski, H.1
  • 16
    • 0000954081 scopus 로고    scopus 로고
    • Biosynthesis and reactions of homocysteine thiolactone
    • Jacobson, D, Carmel, R, eds, Cambridge University Press, UK
    • Jakubowski, H., Biosynthesis and reactions of homocysteine thiolactone. In Jacobson, D., Carmel, R., eds, Homocysteine in Health and Disease, Cambridge University Press, UK, 2001, pp 21-31.
    • (2001) Homocysteine in Health and Disease , pp. 21-31
    • Jakubowski, H.1
  • 17
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis
    • Wald, D.S., Law, M. and Morris, J.K., Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. Br. Med J. 2002, 325:1202-1209.
    • (2002) Br. Med J , vol.325 , pp. 1202-1209
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 18
    • 0035513846 scopus 로고    scopus 로고
    • Translational accuracy of aminoacyl-tRNA synthetases: Implications for atherosclerosis
    • Jakubowski, H., Translational accuracy of aminoacyl-tRNA synthetases: Implications for atherosclerosis. J. Nutr. 2001, 131(suppl): 2983-2987.
    • (2001) J. Nutr , vol.131 , Issue.SUPPL. , pp. 2983-2987
    • Jakubowski, H.1
  • 19
    • 10644236918 scopus 로고    scopus 로고
    • Editing of Errors in Amino Acid Selection for Protein Synthesis
    • Ibba, M, Francklyn, C, Cusack, S, eds, Landes Bioscience, Georgetown, TX
    • Jakubowski, H., Editing of Errors in Amino Acid Selection for Protein Synthesis. In The Aminoacyl-tRNA Synthetases (Ibba, M., Francklyn, C., Cusack, S. (eds.), Landes Bioscience, Georgetown, TX, 2005, pp.384-396.
    • (2005) The Aminoacyl-tRNA Synthetases , pp. 384-396
    • Jakubowski, H.1
  • 20
    • 0031035742 scopus 로고    scopus 로고
    • Metabolism of homocysteine thiolactone in human cell cultures: Possible mechanism for pathological consequences of elevated homocysteine levels
    • Jakubowski, H., Metabolism of homocysteine thiolactone in human cell cultures: Possible mechanism for pathological consequences of elevated homocysteine levels. J. Biol. Chem. 1997, 272: 1935-1941.
    • (1997) J. Biol. Chem , vol.272 , pp. 1935-1941
    • Jakubowski, H.1
  • 21
    • 0032778517 scopus 로고    scopus 로고
    • Protein homocysteinylation: Possible mechanism underlying pathological consequences of elevated homocysteine levels
    • Jakubowski, H., Protein homocysteinylation: Possible mechanism underlying pathological consequences of elevated homocysteine levels. FASEB J. 1999, 13: 2277-2283.
    • (1999) FASEB J , vol.13 , pp. 2277-2283
    • Jakubowski, H.1
  • 22
    • 0037163003 scopus 로고    scopus 로고
    • Homocysteine is a protein amino acid in humans: Implications for homocysteine-linked disease
    • Jakubowski, H., Homocysteine is a protein amino acid in humans: Implications for homocysteine-linked disease. J. Biol. Chem. 2002, 277: 30425-30428.
    • (2002) J. Biol. Chem , vol.277 , pp. 30425-30428
    • Jakubowski, H.1
  • 23
    • 2542618547 scopus 로고    scopus 로고
    • Autoantibodies against N-homocysteinylated proteins in humans: Implications for atherosclerosis
    • Undas, A., Perła, J., Łaciński, M., Trzeciak, W.H., Kaźmierski, R. and Jakubowski, H., Autoantibodies against N-homocysteinylated proteins in humans: Implications for atherosclerosis. Stroke 2004, 35: 1299-1304.
    • (2004) Stroke , vol.35 , pp. 1299-1304
    • Undas, A.1    Perła, J.2    Łaciński, M.3    Trzeciak, W.H.4    Kaźmierski, R.5    Jakubowski, H.6
  • 24
    • 13844253976 scopus 로고    scopus 로고
    • Jankowski, M., Twardowska, M., Padjas, A., Jakubowski, H. and Szczeklik, A., Antibodies to N-homocysteinylated albumin as a marker for early-onset coronary artery disease in men
    • Undas, A., Jankowski, M., Twardowska, M., Padjas, A., Jakubowski, H. and Szczeklik, A., Antibodies to N-homocysteinylated albumin as a marker for early-onset coronary artery disease in men. Thromb Haemost 2005, 93: 346-350.
    • (2005) Thromb Haemost , vol.93 , pp. 346-350
    • Undas, A.1
  • 25
    • 28344446460 scopus 로고    scopus 로고
    • Mechanisms of homocysteine-induced atherothrombosis
    • Lentz, S.R., Mechanisms of homocysteine-induced atherothrombosis. J. Thromb. Haemost. 2005, 3: 1646-1654.
    • (2005) J. Thromb. Haemost , vol.3 , pp. 1646-1654
    • Lentz, S.R.1
  • 26
    • 2442572249 scopus 로고    scopus 로고
    • Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4
    • Roybal, C.N., Yang, S., Sun, C.W., Hurtado, D., Vander Jagt D.L., Townes, T.M. and Abcouwer, S.F., Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4. J. Biol. Chem. 2004, 279: 14844-14852.
    • (2004) J. Biol. Chem , vol.279 , pp. 14844-14852
    • Roybal, C.N.1    Yang, S.2    Sun, C.W.3    Hurtado, D.4    Vander Jagt, D.L.5    Townes, T.M.6    Abcouwer, S.F.7
  • 28
    • 0035936847 scopus 로고    scopus 로고
    • Genetic determinants of homocysteine thiolactonase activity in humans: Implications for atherosclerosis
    • Jakubowski, H., Ambrosius, W. and Pratt, J.H., Genetic determinants of homocysteine thiolactonase activity in humans: Implications for atherosclerosis. FEBS Lett.2001, 491: 35-39.
    • (2001) FEBS Lett , vol.491 , pp. 35-39
    • Jakubowski, H.1    Ambrosius, W.2    Pratt, J.H.3
  • 29
    • 0034617073 scopus 로고    scopus 로고
    • Homocysteine thiolactone and protein homocysteinylation in human endothelial cells: Implications for atherosclerosis
    • Jakubowski, H., Zhang, L., Bardeguez, A. and Aviv, A., Homocysteine thiolactone and protein homocysteinylation in human endothelial cells: Implications for atherosclerosis. Circ. Res. 2000, 87: 45-51.
    • (2000) Circ. Res , vol.87 , pp. 45-51
    • Jakubowski, H.1    Zhang, L.2    Bardeguez, A.3    Aviv, A.4
  • 31
    • 0036750807 scopus 로고    scopus 로고
    • The determination of homocysteinethiolactone in biological samples
    • Jakubowski, H., The determination of homocysteinethiolactone in biological samples. Anal. Biochem. 2002, 308: 112-119.
    • (2002) Anal. Biochem , vol.308 , pp. 112-119
    • Jakubowski, H.1
  • 32
    • 13244287981 scopus 로고    scopus 로고
    • The determination of homocysteine- thiolactone in human plasma
    • Chwatko, G. and Jakubowski, H., The determination of homocysteine- thiolactone in human plasma. Anal. Biochem. 2005, 337: 271-277.
    • (2005) Anal. Biochem , vol.337 , pp. 271-277
    • Chwatko, G.1    Jakubowski, H.2
  • 33
    • 12944309749 scopus 로고    scopus 로고
    • Urinary excretion of homocysteine- thiolactone in humans
    • Chwatko, G. and Jakubowski, H., Urinary excretion of homocysteine- thiolactone in humans. Clin. Chem. 2005, 51: 408-415.
    • (2005) Clin. Chem , vol.51 , pp. 408-415
    • Chwatko, G.1    Jakubowski, H.2
  • 34
    • 17644367506 scopus 로고    scopus 로고
    • Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase
    • Khersonsky, O. and Tawfik, D.S., Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase. Biochemistry 2005, 44: 6371-6382.
    • (2005) Biochemistry , vol.44 , pp. 6371-6382
    • Khersonsky, O.1    Tawfik, D.S.2
  • 35
    • 4444307712 scopus 로고    scopus 로고
    • The role of paraoxonase 1 activity in cardiovascular disease: Potential for therapeutic intervention
    • Mackness, M,I., Durrington, P.N. and Mackness, B., The role of paraoxonase 1 activity in cardiovascular disease: potential for therapeutic intervention. Am. J. Cardiovasc. Drugs 2004, 4: 211-217.
    • (2004) Am. J. Cardiovasc. Drugs , vol.4 , pp. 211-217
    • Mackness, M.I.1    Durrington, P.N.2    Mackness, B.3
  • 36
    • 0344951233 scopus 로고    scopus 로고
    • Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins
    • Gouedard, C., Koum-Besson, N., Barouki, R. and Morel, Y., Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins. Mol. Pharmacol. 2003, 63: 945-956.
    • (2003) Mol. Pharmacol , vol.63 , pp. 945-956
    • Gouedard, C.1    Koum-Besson, N.2    Barouki, R.3    Morel, Y.4
  • 37
    • 0242721909 scopus 로고    scopus 로고
    • Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: A role for sterol regulatory element-binding protein-2
    • Deakin, S., Leviev, I., Guernier, S. and James, R.W., Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: a role for sterol regulatory element-binding protein-2. Arterioscler. Thromb. Vasc. Biol. 2003, 23: 2083-2089.
    • (2003) Arterioscler. Thromb. Vasc. Biol , vol.23 , pp. 2083-2089
    • Deakin, S.1    Leviev, I.2    Guernier, S.3    James, R.W.4
  • 38
    • 0347594016 scopus 로고    scopus 로고
    • Effect of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins) on tissue paraoxonase 1 and plasma platelet activating factor acetylhydrolase activities
    • Beltowski, J., Wojcicka, G., Jamroz, A., Effect of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins) on tissue paraoxonase 1 and plasma platelet activating factor acetylhydrolase activities. J. Cardiovasc. Pharmacol. 2004, 43: 121-127.
    • (2004) J. Cardiovasc. Pharmacol , vol.43 , pp. 121-127
    • Beltowski, J.1    Wojcicka, G.2    Jamroz, A.3
  • 39
    • 0033817620 scopus 로고    scopus 로고
    • Effect of simvastatin therapy on paraoxonase activity and related lipoproteins in familial hypercholesterolemic patients
    • Tomas, M., Senti, M., Garcia-Faria, F., Vila, J., Torrents, A., Covas, M. and Marrugat, J., Effect of simvastatin therapy on paraoxonase activity and related lipoproteins in familial hypercholesterolemic patients. Arterioscler. Thromb. Vasc. Biol. 2000, 20: 2113-2119.
    • (2000) Arterioscler. Thromb. Vasc. Biol , vol.20 , pp. 2113-2119
    • Tomas, M.1    Senti, M.2    Garcia-Faria, F.3    Vila, J.4    Torrents, A.5    Covas, M.6    Marrugat, J.7


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