Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells

Journal of Biomedical Materials Research - Part A

Volumn 81, Issue 2, 2007, Pages 259-268

  Benoit, Danielle S W ^a   Tripodi, Margaret C ^a   Blanchette, James O ^b   Langer, Steve J ^b   Leinwand, Leslie A ^b   Anseth, Kristi S ^a,b  

^a UCB 450   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Poly(ethylene glycol); Protein kinase B; Stem cells; Three dimensional cell culture

Indexed keywords

CELL CULTURE; CELLS; HYDROGELS; POLYETHYLENE GLYCOLS;

CELL-MATRIX INTERACTIONS; PROTEIN KINASE B; STEM CELLS; THREE-DIMENSIONAL CELL CULTURE;

ENZYME KINETICS;

INTEGRIN LINKED KINASE; MACROGOL; PROTEIN KINASE B; RECOMBINASE; VINCULIN;

ADENOVIRUS; ANOIKIS; ARTICLE; CELL CULTURE; CELL ENCAPSULATION; CELL INTERACTION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; HYDROGEL; MESENCHYME CELL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STEM CELL;

ANOIKIS; BIOCOMPATIBLE MATERIALS; CELLS, CULTURED; EXTRACELLULAR MATRIX; HUMANS; HYDROGELS; MATERIALS TESTING; MESENCHYMAL STEM CELLS; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; VINCULIN;

EID: 34247624143     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31292     Document Type: Article

References (33)

1. Koenig A, Grainger D.Cell adhesion-dependent signaling pathways on biomaterials surfaces. In:Dillow A, Lowman A, editors. Biomimetic Materials and Design. New York: Marcel Dekker; 2002. p 187.
2. Longhurst C, Jennings L. Integrin-mediated signal transduction. Cell Mol Life Sci 1998;54:514-526.
3. Ishaug SL, Thomson RC, Mikos AG, Langer R.Biomaterials for organ regeneration. In: Meyers RA, editor. Molecular Biology and Biotechnology: A Comprehensive Desk Reference. New York: Wiley-VCH; 1995. pp 86-93.
4. Howe A, Aplin AE, Alahari SK, Juliano RL. Integrin signaling and cell growth control. Curr Opin Cell Biol 1992;10:220-231.
5. Alahari SK, Reddig PJ, Juliano RL. Biological aspects of signal transduction by cell adhesion receptors. Int Rev Cytol 2002;220:145-184.
6. Nicholson KM, Anderson NG. The protein kinase B/Akt signaling pathway in human malignancy. Cell Signal 2002;14:381-395.
7. Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, Bell JC, Dedhar S. Regulation of cell adhesion and anchorage-dependent growth by a new β 1-integrin-linked protein kinase. Nature 1996;379:91-96.
8. Wu C. PINCH, N(i)ck and the ILK: Network wiring at cell-matrix adhesions. Trends Cell Biol 2005;15:460-466.
9. Abbott A. Cell culture: Biology's new dimension. Nature 2003;424:870-872.
10. Langer R, Tirrell DA. Designing materials for biology and medicine. Nature 2004;428:487-491.
11. Nuttelman CR, Tripodi MC, Anseth KS. In vitro osteogenic differentiation of human mesenchymal stem cells photoencapsulated in PEG hydrogels. J Biomed Mater Res A 2004;68:773-782.
12. Pinske GGM, Jiawan-Lalai R, Bruijn JA, de Heer E. RGD peptides confer survival to hepatocytes via the β1-integrin-ILK-pAkt-pathway. J Hepatol 2005;42:87-93.
13. Sawhney AS, Pathak CP, Hubbell JA. Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(α-hydroxy acid) diacrylate macromers. Macromolecules 1993;26:581-587.
14. Hern DL, Hubbell JA. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J Biomed Mater Res 1998;39:266-276.
15. Bryant SJ, Nuttelman CR, Anseth KS. Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 fibroblasts. J Biomater Sci Polym Ed 2000;11:439-457.
16. Nuttelman CR, Tripodi MC, Anseth KS. Synthetic hydrogel niches that promote hMSC viability. Matrix Biol 2005;24:208-218.
17. Nuttelman CR, Benoit DSW, Tripodi MC, Anseth KS. The effect of ethylene glycol methacrylate phosphate in PEG hydrogels on mineralization and viability of encapsulated hMSCs. Biomaterials 2006;27:1377-1386.
18. Stupack DG, Cheresh DA. Get a ligand, get a life: Integrins, signaling and cell survival. J Cell Sci 2002;115:3729-3738.
19. Yamada KM, Miyamoto S, Aota S, Katz BZ. Fibronectin and integrin signaling and cytoskeleral regulation. FASEB J 1996;10:2433.
20. Ginocotti FG, Ruoslahti E. Integrin signaling. Science 1999;285:1028-1032.
21. Cardone MH, Alvesen GS, Widmann C, Johnson G, Frisch SM. The regulation of anoikis: MEKK-1 activation requires cleavage by caspases. Cell 1997;90:315-323.
22. Dedhar S, Williams B, Hannigan G. Integrin linked kinase: A regulator of integrin and growth factor signaling. Trends Cell Biol 1999;9:319-323.
23. Miyamoto S, Teramoto H, Gutkind JS, Yamada KM. Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors. J Cell Biol 1996;135:1633-1642.
24. Khwaja A, Rodriguez-Viciana R, Wennstrom S, Warne PH, Downward J. Matrix adhesion and ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J 1997;16:2783-2793.
25. Ortega-Velazquez R, Diez-Marques ML, Ruiz-Torres MP, Gonzales-Rubio M, Rodriguez-Puyol M, Rodriguez PD. Arg-Gly-Asp-Ser (RGDS) peptide stimulates transforming growth factor β1 transcription and secretion through integrin activation. FASEB J 2003;17:1529-1531.
26. Gary DS, Milhavet O, Camandola S, Mattson MP. Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons. J Neurochem 2003;84:878-890.
27. Tashiro K, Moniji A, Woshida I, Hayashi Y, Matsuda K, Tasiro N. An IKLLI-containing peptide derived from the laminin α1 chain mediating heparin-binding, cell adhesion, neurite outgrowth and proliferation, represents a binding site for integrin α3β1 and heparan sulphate proteoglycan. Biochem J 1999;340:119-126.
28. Mann BK, Tsai AT, Scott-Burden T, West JL. Modification of surfaces with cell adhesion peptides alters extracellular matrix deposition. Biomaterials 1999;20:2281-2286.
29. Benoit DSW, Anseth KS. The effect on osteoblast function of colocalized RGD and PHSRN epitopes on PEG surfaces. Biomaterials 2005;26:5209-5220.
30. Beier F. Cell-cycle control and the cartilage growth plate. J Cell Physiol 2005;202:1-8.
31. Somasiri A, Howarth A, Goswami D, Dedhar S, Roskelley CD. Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells. J Cell Sci 2000;114:1125-1136.
32. Huang Y, Li J, Zhang Y, Wu C. The roles of integrin-linked kinase in the regulation of myogenic differentiation. J Cell Biol 2000;150:861-871.
33. Miller MG, Naruszewicz I, Kumar AS, Ramlal T, Hannigan GE. Integrin-linked kinase is a positive mediator of L6 myoblast differentiation. Biochem Biophys Res Commun 2003;310:796-803.