Pro-inflammatory cytokines gene polymorphisms in Rheumatoid Arthritis

Central-European Journal of Immunology

Volumn 31, Issue 3-4, 2006, Pages 117-122

  Paradowska, Agnieszka ^a   Ła̧cki, Jan K ^a  

^a INSTITUTE OF RHEUMATOLOGY   (Poland)

Author keywords

Gene polymorphism; Interleukin 1; Interleukin 6; Rheumatoid arthritis; Tumor necrosis factor

Indexed keywords

CYCLOOXYGENASE 2; CYTOKINE; HLA DR ANTIGEN; INTERLEUKIN 1; INTERLEUKIN 6; NITRIC OXIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

AUTOCRINE EFFECT; BONE DEFECT; CELL PROLIFERATION; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; DISEASE SEVERITY; ENDOCRINE FUNCTION; ENZYME ACTIVATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HELPER CELL; HUMAN; IMMUNE RESPONSE; JOINT DESTRUCTION; PARACRINE SIGNALING; PATHOGENESIS; PROTEIN EXPRESSION; REVIEW; RHEUMATOID ARTHRITIS; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SYNOVIAL FLUID;

EID: 34247602985     PISSN: 14263912     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. Lacki JK, Muller-Ruchholtz W, Mackiewicz SH (1997): Does cyclophosphamide combined with methylprednisolone affect the expression of leukocyte function associated antigen 1 in refractory rheumatoid arthritis. Arch Immunol Ther Exp (Warsz) 45: 285-288.
2. Lacki JK, Moser R, Korczowska I, et al. (2000): TNF-alpha gene polymorphisms does not affect the clinical and radiological outcome of rheumatoid arthritis. Rheumatol Int 19: 137-140.
3. Clifton O (2002): The Pathogenesis of Rheumatoid Arthritis: Piviotal Cytokines Involved in Bone Degradation and Inflammation. J Rheumatol 29: 3-9.
4. Das G, Sheridan S, Janeway CA Jr (2001): The source of early IFN-gamma that plays a role in Th1 priming. J Immunol 167: 2004-2010.
5. Filipowicz-Sosnowska A, Przygodzka M (2001): Diagnostyka wczesnego reumatoidalnego zapalenia stawów (rzs). Przew Lek 4: 12-18.
6. Panayi GS (2005): B cells: a fundamental role in the pathogenesis of rheumatoid arthritis? Rheumatology (Oxford) 44 Suppl 2: ii3-ii7.
7. Buch M, Emery P (2002): The aetiology and pathogenesis of Rheumatoid Arthritis. Hosp Pharmacist 9: 5-10.
8. Lacki JK, Korczowska I, Mackiewicz SH (1998): The role of MHC class II genes in the etiopathogenesis of rheumatoid arthritis. Przegl Lek 55: 524-527.
9. Cvetkovic J, Wallberg-Jonsson S, Stegmayr B, et al. (2002): Susceptibility for and clinical manifestations of rheumatoid arthritis are associated with polymorphisms of the TNF-alpha, IL-1beta and IL-1Ra genes. J Rheumatol 29: 212-219.
10. Rozwadowska N, Fiszer D, Kurpisz M (2005): Function of the interleukin-1 gene system in immunomodulation, apoptosis and proliferation in the male gonad. Postepy Hig Med Dosw (Online) 59: 56-67.
11. Christodoulou C, Choy EH (2006): Joint inflammation and cytokine inhibition in rheumatoid arthritis. Clin Exp Med 6: 13-9.
12. Granet C, Maslinski W, Miossec P (2004): Increased AP-1 and NF-kappaB activation and recruitment with the combination of the proinflammatory cytokines IL-1beta, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes. Arthritis Res Ther 6: R190-R198.
13. Cantargel A, Navaux F, Loubet-Lescoulie P, et al. (1999): Interleukin-1beta, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene polymorphisms: relationship to occurrence and severity of rheumatoid arthritis. Arthritis Rheum 42: 1093-1100.
14. Pawlik A, Kurzawski M, Florczak M, et al. (2005): IL1beta+3953 exon 5 and IL-2-330 promoter polymorphisms in patients with rheumatoid arthritis. Clin Exp Rheumatol 23: 159-164.
15. Buchs N, di Giovine FS, Silvestri T, et al. (2001): IL-1B and IL-1Ra gene polymorphisms and disease severity in rheumatoid arthritis: interaction with their plasma levels. Genes Immun 2: 222-228.
16. Zhang X, Llamado L, Pillay I, et al. (2002): Interleukin-1 gene polymorphism disease activity and bone mineral metabolism in rheumatoid arthritis. Chin Med J (Engl) 115: 46-49.
17. Combe B, Pope RM, Fischbach M, et al. (1985): Interleukin-2 in the rheumatoid arthritis: production of and response to interleukin-2 in rheumatoid synovial fluid, synovial tissue and peripheral blood. Clin Exp Immunol 59: 520-528.
18. Bushley AW, Ferrell R, McDuffie K, et al. (2004): Polymorphisms of interleukin (IL) - 1alpha, IL-1beta, IL-6, IL-10, and IL-18 and the risk of ovarian cancer. Gynecol Oncol 95: 672-679.
19. Schwarz MJ, Kronig H, Riedel M, et al. (2006): IL-2 and IL-4 polymorphisms as candidate genes in schizophrenia. Eur Arch Psychiatry Clin Neurosci 256: 72-76.
20. Fedetz M, Matesanz F, Caliz R, et al. (2003): Lack of association between -384 and 114 IL-2 gene polymorphisms and rheumatoid arthritis. J Rheumatol 30: 435-437.
21. Lipinska-Gediga M, Mierzchała M, Kubler A, et al. (2004): Interleukina-6 i prokalcytonina - wartość prognostyczna i dyskryminacyjna oznaczeń u pacjentów oddziału intensywnej terapii i poddanych rozległym zabiegom operacyjnym. Pol Przegl Kardiol 6: 57-62.
22. Klimiuk PA, Sierakowski S, Gindzienska-Sieskiewicz E, Chwiecko J (2005): Przydatność oznaczania w surowicy krwi stȩżeń interleukiny 6 (IL-6), metaloproteinaz i ich tkankowych inhibitorów w ocenie aktywności reumatoidalnego zapalenia stawów. Reumatologia 5: 239-242.
23. Ferrari SL, Ahn-Luong L, Garnero P, et al. (2003): Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women. J Clin Endocrinol Metab 88: 255-259.
24. Jerrard-Dunne P, Sitzer M, Risley P, et al. (2003): Interleukin-6 promoter polymorphism modulates the effects of heavy alcohol consumption on early carotid artery atherosclerosis: the Carotid Atherosclerosis Progression Study (CAPS). Stroke 34: 402-407.
25. Komatsu Y, Tai H, Galicia JC, et al. (2005): Interleukin-6 (JL-6)-373 A9T11 allels is associated with reduced susceptibility to chronic periodontitis in Japanese subjects and decreased serum IL-6 level. Tissue Antigens 65: 110-114.
26. Kotake S, Udagawa N, Takahashi N, et al. (1999): IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 103: 1345-1352.
27. Kehlen A, Pachnio A, Thiele K, et al. (2003): Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6. Arthritis Res Ther 5: 186-192.
28. Hwang SY, Kim HY (2004): Expression of IL-17 homolgos and their receptors in the synovial cells of rheumatoid arthritis patients. Mol Cells 19: 180-184.
29. Chabaud M, Lubberts E, Joosten L, et al. (2001): IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis. Arthritis Res 3: 168-177.
30. Rink L, Kirchner H (1996): Recent progress in the tumor necrosis factor-alpha field. Int Arch Allergy Immunol 11: 199-209.
31. Yen JH, Chen CJ, Tsai W, et al. (2001): Tumor necrosis factor promoter polymorphisms in patients with rheumatoid arthritis in Taiwan. J Rheumatol 28: 1788-1792.
32. Rodriguez-Carreon AA, Zuniga J, Hernandez-Pacheco G, et al. (2005): Tumor necrosis factor-alpha -308 promoter polymorphism contributes independently to HLA alleles in the severity of rheumatoid arthritis in Mexicans. J Autoimmun 24: 63-68.
33. Fabris M, Di PE, D'Elia A, et al. (2002): Tumor necrosis factor-alpha gene polymorphism in severe and mild-moderate rheumatoid arthritis. J Rheumatol 29: 29-33.
34. Low AS, Gonzalez-Gay MA, Akil M, et al. (2002): TNF+489 polymorphism does not contribute to susceptibility to rheumatoid arthritis. Clin Exp Rheumatol 20: 829-832.