Large-conductance Ca2+-activated K+ currents blocked and impaired by homocysteine in human and rat mesenteric artery smooth muscle cells

Life Sciences

Volumn 80, Issue 22, 2007, Pages 2060-2066

  Cai, Benzhi ^a   Gong, Dongmei ^a   Pan, Zhenwei ^a   Liu, Yu ^a   Qian, Hong ^a   Zhang, Yong ^a   Jiao, Jundong ^a   Lu, Yanjie ^a   Yang, Baofeng ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Biology Medicine Province Ministry   (China)

Author keywords

BKCa; Electrophysiology; Homocysteine; Mesenteric artery smooth muscle cells

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; HOMOCYSTEINE; CALCIUM; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; ISOLATED ARTERY; MALE; MESENTERIC ARTERY; NONHUMAN; PATCH CLAMP; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; RAT; RISK FACTOR; SMOOTH MUSCLE FIBER; STATISTICAL SIGNIFICANCE; VASCULAR DISEASE; ANIMAL; BLOOD; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; MUSCLE RELAXATION; VASCULAR SMOOTH MUSCLE; WISTAR RAT;

RATTUS;

ANIMALS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; HOMOCYSTEINE; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MEMBRANE POTENTIALS; MESENTERIC ARTERIES; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, WISTAR; VASCULAR DISEASES;

EID: 34247595913     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.03.003     Document Type: Article

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